6J15
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![BU of 6j15 by Molmil](/molmil-images/mine/6j15) | Complex structure of GY-5 Fab and PD-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | Authors: | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | Deposit date: | 2018-12-27 | Release date: | 2019-11-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy. Iscience, 14, 2019
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2OR8
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![BU of 2or8 by Molmil](/molmil-images/mine/2or8) | Tim-1 | Descriptor: | ACETATE ION, Hepatitis A virus cellular receptor 1 homolog | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Casasnovas, J.M. | Deposit date: | 2007-02-02 | Release date: | 2007-04-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family. Immunity, 26, 2007
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2P1Y
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1I85
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![BU of 1i85 by Molmil](/molmil-images/mine/1i85) | CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX | Descriptor: | CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD86 | Authors: | Schwartz, J.-C.D, Zhang, X, Fedorov, A.A, Nathenson, S.G, Almo, S.C. | Deposit date: | 2001-03-12 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature, 410, 2001
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2OR7
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![BU of 2or7 by Molmil](/molmil-images/mine/2or7) | Tim-2 | Descriptor: | ACETATE ION, T-cell immunoglobulin and mucin domain-containing protein 2 | Authors: | Santiago, C, Ballesteros, A, Kaplan, G.G, Casasnovas, J.M. | Deposit date: | 2007-02-02 | Release date: | 2007-04-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family. Immunity, 26, 2007
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2NMS
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![BU of 2nms by Molmil](/molmil-images/mine/2nms) | |
2OTU
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![BU of 2otu by Molmil](/molmil-images/mine/2otu) | Crystal structure of Fv polyglutamine complex | Descriptor: | Fv heavy chain variable domain, Fv light chain variable domain, peptide antigen | Authors: | Li, P. | Deposit date: | 2007-02-09 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy To be Published
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2OYP
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![BU of 2oyp by Molmil](/molmil-images/mine/2oyp) | T Cell Immunoglobulin Mucin-3 Crystal Structure Revealed a Galectin-9-independent Binding Surface | Descriptor: | Hepatitis A virus cellular receptor 2, SULFATE ION | Authors: | Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C. | Deposit date: | 2007-02-22 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface Immunity, 26, 2007
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1J05
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![BU of 1j05 by Molmil](/molmil-images/mine/1j05) | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment | Descriptor: | GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ... | Authors: | Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I. | Deposit date: | 2002-11-01 | Release date: | 2003-12-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment To be Published
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6L7Z
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![BU of 6l7z by Molmil](/molmil-images/mine/6l7z) | Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | Descriptor: | Butyrophilin-like protein 2 | Authors: | Basak, A.J, Lee, W, Samanta, D, De, S. | Deposit date: | 2019-11-03 | Release date: | 2020-10-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors. J.Mol.Biol., 432, 2020
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2N4I
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![BU of 2n4i by Molmil](/molmil-images/mine/2n4i) | The solution structure of Skint-1, a critical determinant of dendritic epidermal gamma-delta T cell selection | Descriptor: | Selection and upkeep of intraepithelial T-cells protein 1 | Authors: | Salim, M, Knowles, T.J, Hart, R, Mohammed, F, Woodward, M.J, Willcox, C.R, Overduin, M, Hayday, A.C, Willcox, B.E. | Deposit date: | 2015-06-18 | Release date: | 2016-03-02 | Last modified: | 2016-05-11 | Method: | SOLUTION NMR | Cite: | Characterization of a Putative Receptor Binding Surface on Skint-1, a Critical Determinant of Dendritic Epidermal T Cell Selection. J.Biol.Chem., 291, 2016
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6MVL
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![BU of 6mvl by Molmil](/molmil-images/mine/6mvl) | |
2MKW
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![BU of 2mkw by Molmil](/molmil-images/mine/2mkw) | |
2M2D
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![BU of 2m2d by Molmil](/molmil-images/mine/2m2d) | Human programmed cell death 1 receptor | Descriptor: | Programmed cell death protein 1 | Authors: | Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D. | Deposit date: | 2012-12-18 | Release date: | 2013-02-27 | Last modified: | 2013-05-15 | Method: | SOLUTION NMR | Cite: | Structure and interactions of the human programmed cell death 1 receptor. J.Biol.Chem., 288, 2013
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2Q20
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2Q1E
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![BU of 2q1e by Molmil](/molmil-images/mine/2q1e) | |
1BWM
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![BU of 1bwm by Molmil](/molmil-images/mine/1bwm) | A SINGLE-CHAIN T CELL RECEPTOR | Descriptor: | PROTEIN (ALPHA-BETA T CELL RECEPTOR (TCR) (D10)) | Authors: | Hare, B.J, Wyss, D.F, Reinherz, E.L, Wagner, G. | Deposit date: | 1998-09-23 | Release date: | 1999-07-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor. Nat.Struct.Biol., 6, 1999
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1DLF
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![BU of 1dlf by Molmil](/molmil-images/mine/1dlf) | HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 5.25 | Descriptor: | ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S), SULFATE ION | Authors: | Nakasako, M, Takahashi, H, Shimada, I, Arata, Y. | Deposit date: | 1998-07-14 | Release date: | 1999-07-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody. J.Mol.Biol., 291, 1999
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1EK3
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![BU of 1ek3 by Molmil](/molmil-images/mine/1ek3) | KAPPA-4 IMMUNOGLOBULIN VL, REC | Descriptor: | CALCIUM ION, CHLORIDE ION, KAPPA-4 IMMUNOGLOBULIN LIGHT CHAIN VL | Authors: | Pokkuluri, P.R, Huang, D.-B, Raffen, R, Stevens, F.J, Schiffer, M. | Deposit date: | 2000-03-06 | Release date: | 2001-03-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Structure of Amyloidogenic Kappa-4 Immunoglobulin VL, REC To be Published
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1DCL
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1DVF
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![BU of 1dvf by Molmil](/molmil-images/mine/1dvf) | IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX | Descriptor: | FV D1.3, FV E5.2, ZINC ION | Authors: | Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A. | Deposit date: | 1996-04-13 | Release date: | 1996-08-17 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution. J.Mol.Biol., 264, 1996
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1CD0
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![BU of 1cd0 by Molmil](/molmil-images/mine/1cd0) | STRUCTURE OF HUMAN LAMDA-6 LIGHT CHAIN DIMER JTO | Descriptor: | PROTEIN (JTO, A VARIABLE DOMAIN FROM LAMBDA-6 TYPE IMMUNOGLOBULIN LIGHT CHAIN) | Authors: | Pokkuluri, P.R, Solomon, A, Weiss, D.T, Stevens, F.J, Schiffer, M. | Deposit date: | 1999-03-05 | Release date: | 2000-03-06 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tertiary structure of human lambda 6 light chains. Amyloid, 6, 1999
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1CDC
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![BU of 1cdc by Molmil](/molmil-images/mine/1cdc) | CD2, N-TERMINAL DOMAIN (1-99), TRUNCATED FORM | Descriptor: | CD2 | Authors: | Murray, A.J, Barclay, A.N, Brady, R.L. | Deposit date: | 1995-05-23 | Release date: | 1995-09-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | One sequence, two folds: a metastable structure of CD2. Proc.Natl.Acad.Sci.USA, 92, 1995
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1DQT
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![BU of 1dqt by Molmil](/molmil-images/mine/1dqt) | THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4 | Authors: | Ostrov, D.A, Shi, W, Schwartz, J.C, Almo, S.C, Nathenson, S.G. | Deposit date: | 2000-01-05 | Release date: | 2000-10-27 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science, 290, 2000
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1CFV
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![BU of 1cfv by Molmil](/molmil-images/mine/1cfv) | MONOCLONAL ANTIBODY FRAGMENT FV4155 FROM E. COLI | Descriptor: | ESTRONE BETA-D-GLUCURONIDE, MONOCLONAL ANTIBODY FV4155, ZINC ION | Authors: | Trinh, C.H, Phillips, S.E.V. | Deposit date: | 1997-04-11 | Release date: | 1997-10-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity. Structure, 5, 1997
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