8I18
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![BU of 8i18 by Molmil](/molmil-images/mine/8i18) | |
8I12
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![BU of 8i12 by Molmil](/molmil-images/mine/8i12) | InuAMN8 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Glycosyl hydrolase family 32 exo-inulinase | Authors: | Zhou, J.P, Cen, X.L, He, L.M, Zhang, R, Huang, Z.X. | Deposit date: | 2023-01-12 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Cold-active and NaCl-tolerant exo-inulinase InuAMN8. To Be Published
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8I0X
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![BU of 8i0x by Molmil](/molmil-images/mine/8i0x) | Beta-Xylosidase JB13GH39P28 showing salt/ethanol/trypsin tolerance, low-pH/low-Temperature activity, and transformation of notoginsenosides | Descriptor: | Glycoside hydrolase family 39 beta-xylosidase | Authors: | Zhou, J.P, Cao, L.J, Lin, M.Y, Zhang, R, Huang, Z.X. | Deposit date: | 2023-01-11 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | beta-Xylosidase JB13GH39P28(D41G)showing salt/ethanol/trypsin tolerance and transformation of notoginsenosides To Be Published
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8I0M
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![BU of 8i0m by Molmil](/molmil-images/mine/8i0m) | Structure of CDK6 in complex with inhibitor | Descriptor: | 2-[(4-azanylcyclohexyl)amino]-7-cyclopentyl-~{N},~{N}-dimethyl-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Cyclin-dependent kinase 6 | Authors: | Jiang, C, Ye, Y, Huang, Y. | Deposit date: | 2023-01-11 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7772 Å) | Cite: | Structure of CDK6 in complex with inhibitor To Be Published
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8I0J
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![BU of 8i0j by Molmil](/molmil-images/mine/8i0j) | JB13GH39P28 mutant-D41G | Descriptor: | CHLORIDE ION, Glycoside hydrolase family 39 beta-xylosidase | Authors: | Zhou, J.P, Cao, L.J, Lin, M.Y, Zhang, R, Huang, Z.X. | Deposit date: | 2023-01-11 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | beta-Xylosidase JB13GH39P28 (D41G) showing salt/ethanol/trypsin tolerance and transformation of notoginsenosides To Be Published
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8I0D
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![BU of 8i0d by Molmil](/molmil-images/mine/8i0d) | Sb3GT1 375S/Q377H mutant complex with UDP-Glc | Descriptor: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Wang, H.T, Wang, Z.L, Ye, M. | Deposit date: | 2023-01-10 | Release date: | 2023-09-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants. Nat Commun, 14, 2023
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8I0C
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![BU of 8i0c by Molmil](/molmil-images/mine/8i0c) | Crystal structure of Aldo-keto reductase 1C3 complexed with compound S0703 | Descriptor: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Jiang, J, He, S, Liu, Y, Fang, P, Sun, H. | Deposit date: | 2023-01-10 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J.Med.Chem., 66, 2023
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8I05
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![BU of 8i05 by Molmil](/molmil-images/mine/8i05) | Crystal structure of Escherichia coli glyoxylate carboligase double mutant | Descriptor: | 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | Authors: | Kim, J.H, Kim, J.S. | Deposit date: | 2023-01-10 | Release date: | 2023-11-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythrulose. Int.J.Biol.Macromol., 253, 2023
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8I03
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![BU of 8i03 by Molmil](/molmil-images/mine/8i03) | Cryo-EM structure of the SIN3L complex from S. pombe | Descriptor: | Chromatin modification-related protein png2, Histone deacetylase clr6, POTASSIUM ION, ... | Authors: | Wang, C, Guo, Z, Zhan, X. | Deposit date: | 2023-01-10 | Release date: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
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8I02
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![BU of 8i02 by Molmil](/molmil-images/mine/8i02) | Cryo-EM structure of the SIN3S complex from S. pombe | Descriptor: | Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... | Authors: | Wang, C, Guo, Z, Zhan, X. | Deposit date: | 2023-01-10 | Release date: | 2023-05-03 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
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8I01
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![BU of 8i01 by Molmil](/molmil-images/mine/8i01) | Crystal structure of Escherichia coli glyoxylate carboligase | Descriptor: | 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | Authors: | Kim, J.H, Kim, J.S. | Deposit date: | 2023-01-10 | Release date: | 2023-11-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Engineering of two thiamine diphosphate-dependent enzymes for the regioselective condensation of C1-formaldehyde into C4-erythrulose. Int.J.Biol.Macromol., 253, 2023
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8HZW
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![BU of 8hzw by Molmil](/molmil-images/mine/8hzw) | The NMR structure of noursinH11W peptide | Descriptor: | noursinH11W | Authors: | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | Deposit date: | 2023-01-09 | Release date: | 2023-05-31 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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8HZV
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![BU of 8hzv by Molmil](/molmil-images/mine/8hzv) | The crystal structure of a Radical SAM Enzyme DesII | Descriptor: | GLYCEROL, IRON/SULFUR CLUSTER, METHIONINE, ... | Authors: | Hou, X.L, Zhou, J.H. | Deposit date: | 2023-01-09 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.33001685 Å) | Cite: | Mechanistic Insights from the Crystal Structure and Computational Analysis of the Radical SAM Deaminase DesII. Adv Sci, 2024
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8HZR
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![BU of 8hzr by Molmil](/molmil-images/mine/8hzr) | Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332 | Descriptor: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Zeng, X.Y, Zhang, J, Li, J. | Deposit date: | 2023-01-09 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystal structure of SARS-Cov-2 main protease
S46F mutant in complex with PF07321332 To Be Published
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8HZ9
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![BU of 8hz9 by Molmil](/molmil-images/mine/8hz9) | Crystal structure of AtHPPD-Y181136 complex | Descriptor: | 4-hydroxyphenylpyruvate dioxygenase, 5-methyl-6-[(2-methyl-3-oxidanylidene-1H-pyrazol-4-yl)carbonyl]-3-propan-2-yl-1,2,3-benzotriazin-4-one, COBALT (II) ION | Authors: | Dong, J, Lin, H.-Y, Yang, G.-F. | Deposit date: | 2023-01-08 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.011 Å) | Cite: | Crystal structure of AtHPPD-Y181136 complex To Be Published
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8HYL
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![BU of 8hyl by Molmil](/molmil-images/mine/8hyl) | Crystal structure of DO1 Fv-clasp fragment | Descriptor: | VH-SARAH, VL-SARAH | Authors: | Anan, Y, Lu, P, Nagata, K, Itakura, M, Uchida, K. | Deposit date: | 2023-01-06 | Release date: | 2024-02-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular and structural basis of anti-DNA antibody specificity for pyrrolated proteins. Commun Biol, 7, 2024
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8HYI
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![BU of 8hyi by Molmil](/molmil-images/mine/8hyi) | Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine | Descriptor: | 2-(2-methyl-5-phenyl-1H-indole-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ... | Authors: | Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K. | Deposit date: | 2023-01-06 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Modulation of a conformational ensemble by a small molecule that inhibits key protein-protein interactions involved in cell adhesion. Protein Sci., 32, 2023
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8HYF
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![BU of 8hyf by Molmil](/molmil-images/mine/8hyf) | Crystal Structure of Banana Lectin In-complex with Fucose at 2.95 A Resolution | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Rasheed, S, Arif, R, Huda, N, Ahmad, M.S, Mateen, S.M. | Deposit date: | 2023-01-06 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of Banana Lectin in-Complex with L-Fucose at 2.95 A Resolution To Be Published
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8HYE
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![BU of 8hye by Molmil](/molmil-images/mine/8hye) | Structure of amino acid dehydrogenase-2752 with ligand | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Alanine dehydrogenase, ... | Authors: | Sakuraba, H, Ohshima, T. | Deposit date: | 2023-01-06 | Release date: | 2023-04-05 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Two different alanine dehydrogenases from Geobacillus kaustophilus: Their biochemical characteristics and differential expression in vegetative cells and spores. Biochim Biophys Acta Proteins Proteom, 1871, 2023
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8HYA
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8HY6
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![BU of 8hy6 by Molmil](/molmil-images/mine/8hy6) | Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-phenethylthiazole-4-carboxylic acid | Descriptor: | 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... | Authors: | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | Deposit date: | 2023-01-05 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HY3
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![BU of 8hy3 by Molmil](/molmil-images/mine/8hy3) | |
8HY0
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![BU of 8hy0 by Molmil](/molmil-images/mine/8hy0) | |
8HXY
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![BU of 8hxy by Molmil](/molmil-images/mine/8hxy) | |
8HXX
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![BU of 8hxx by Molmil](/molmil-images/mine/8hxx) | Cryo-EM structure of the histone deacetylase complex Rpd3S | Descriptor: | Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
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