PDB: 243083 resultsInfo pagesStatus searchChemie searchBIRD

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4RKA	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347 Descriptor: 2-{[5-(naphthalen-1-ylmethyl)-4-oxo-4H-1lambda~4~,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... Authors: Zhu, L, Ren, X, Zhu, J, Li, H. Deposit date: 2014-10-12 Release date: 2015-11-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347 TO BE PUBLISHED
1ED5	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH NNA(H4B FREE) Descriptor: ACETATE ION, CACODYLIC ACID, GLYCEROL, ... Authors: Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. Deposit date: 2000-01-26 Release date: 2001-01-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. Biochemistry, 40, 2001
5RAQ	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001577a Descriptor: 2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanenitrile, CHLORIDE ION, Lysine-specific demethylase 3B, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAF	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001559a Descriptor: (5~{R})-3,4,4-trimethyl-5-(oxidanylamino)-1,3-thiazolidine-2-thione, CHLORIDE ION, Lysine-specific demethylase 3B, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.62 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAU	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with DA000165b Descriptor: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.73 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
4FGL	Reduced quinone reductase 2 in complex with chloroquine Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... Authors: Leung, K.K, Shilton, B.H. Deposit date: 2012-06-04 Release date: 2013-03-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Crystal structures of quinone reductase 2 bound to antimalarial drugs reveal conformational change upon reduction J.Biol.Chem., 2013
5RAH	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM010032a Descriptor: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.66 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
4FDC	Crystal structure of the E493V mutant of human apoptosis inducing factor (AIF) Descriptor: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE Authors: Sevrioukova, I.F. Deposit date: 2012-05-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Am.J.Hum.Genet., 91, 2012
4JTO	Cysteine bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys and dithionite Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION Authors: Driggers, C.M, Karplus, P.A. Deposit date: 2013-03-23 Release date: 2013-06-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH. J.Mol.Biol., 425, 2013
5FYS	Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate Descriptor: (2R)-2-hydroxypentanedioic acid, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Nowak, R, Kopec, J, Johansson, C, Gileadi, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2016-03-09 Release date: 2017-03-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with D-2-Hydroxyglutarate To be Published
4RLI	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... Authors: Zhu, L, Ren, X, Zhu, J, Li, H. Deposit date: 2014-10-17 Release date: 2015-11-04 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 TO BE PUBLISHED
1OOQ	Nitroreductase from e-coli in complex with the inhibitor dicoumarol Descriptor: BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase Authors: Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. Deposit date: 2003-03-04 Release date: 2003-04-02 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2 Å) Cite: Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003
1MZZ	Crystal Structure of Mutant (M182T)of Nitrite Reductase Descriptor: COPPER (II) ION, Copper-containing nitrite reductase Authors: Guo, H, Olesen, K, Xue, Y, Shapliegh, J, Sjolin, L. Deposit date: 2002-10-10 Release date: 2004-09-28 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center To be Published
5RAG	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001767a Descriptor: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.52 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAN	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS039080d Descriptor: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... Authors: Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. Deposit date: 2020-03-16 Release date: 2020-04-22 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
2G1M	Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) Descriptor: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE Authors: Mcdonough, M.A, Schofield, C.J. Deposit date: 2006-02-14 Release date: 2006-06-13 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc.Natl.Acad.Sci.Usa, 103, 2006
1VXO	METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ETHYL-S-[2-[BIS(1-METHYLETHYL)AMINO]ETHYL] METHYLPHOSPHONOTHIOATE (VX) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, METHYLPHOSPHONIC ACID ESTER GROUP, PROTEIN (ACETYLCHOLINESTERASE) Authors: Millard, C.B, Silman, I, Sussman, J.L. Deposit date: 1999-04-21 Release date: 1999-11-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Reaction Products of Acetylcholinesterase and VX Reveal a Mobile Histidine in the Catalytic Triad J.Am.Chem.Soc., 121, 1999
1EIL	2,3-DIHYDROXYBIPHENYL-1,2-DIOXYGENASE Descriptor: 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (III) ION, SULFATE ION Authors: Senda, T. Deposit date: 2000-02-26 Release date: 2001-02-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of substrate free and complex forms of reactivated BphC, an extradiol type ring-cleavage dioxygenase. J.Inorg.Biochem., 83, 2001
3W7R	Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097 Descriptor: 2,6-dioxo-5-[2-(4-phenylphenyl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid, ACETATE ION, CHLORIDE ION, ... Authors: Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. Deposit date: 2013-03-06 Release date: 2014-03-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097 To be Published
2BZS	Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex. Descriptor: 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, NRH DEHYDROGENASE [QUINONE] 2, ... Authors: Abu Khader, M.M, Heap, J.T, De Matteis, C, Kellam, B, Doughty, S.W, Minton, N, Paoli, M. Deposit date: 2005-08-22 Release date: 2005-09-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Binding of the Anticancer Prodrug Cb1954 to the Activating Enzyme Nqo2 Revealed by the Crystal Structure of Their Complex. J.Med.Chem., 48, 2005
2BVG	Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) Descriptor: 6-HYDROXY-D-NICOTINE OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE Authors: Koetter, J.W.A, Schulz, G.E. Deposit date: 2005-06-28 Release date: 2005-08-17 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3.18 Å) Cite: Crystal Structure of 6-Hydroxy-D-Nicotine Oxidase from Arthrobacter Nicotinovorans. J.Mol.Biol., 352, 2005
1WZD	Crystal Structure Of An Artificial Metalloprotein: Fe(10-CH2CH2COOH-Salophen)/Wild Type Heme oxygenase Descriptor: GLYCEROL, Heme oxygenase, SULFATE ION, ... Authors: Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. Deposit date: 2005-03-04 Release date: 2006-02-21 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
4HVQ	X-ray crystal structure of FECU reconstituted 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION Authors: Liu, F, Chen, L, Liu, A. Deposit date: 2012-11-06 Release date: 2013-11-27 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.81 Å) Cite: An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE. J.Biol.Chem., 290, 2015
1GPB	GLYCOGEN PHOSPHORYLASE B: DESCRIPTION OF THE PROTEIN STRUCTURE Descriptor: GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE Authors: Johnson, L.N, Acharya, K.R, Stuart, D.I. Deposit date: 1990-06-04 Release date: 1992-10-15 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Glycogen Phosphorylase B: Description of the Protein Structure Glycogen Phosphorylase B: Description of the Protein Structure, 1991
3RVH	Crystal Structure of JMJD2A Complexed with Inhibitor Descriptor: 8-hydroxy-3-(piperazin-1-yl)quinoline-5-carboxylic acid, GLYCEROL, Lysine-specific demethylase 4A, ... Authors: King, O.N.F, Maloney, D.J, Tumber, A, Rai, G, Jadhav, A, Clifton, I.J, Heightman, T.D, Simeonov, A, McDonough, M.A, Schofield, C.J. Deposit date: 2011-05-06 Release date: 2012-05-09 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.251 Å) Cite: Crystal Structure of JMJD2A Complexed with Inhibitor To be Published

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