PDB: 335 resultsInfo pagesStatus searchChemie searchBIRD

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7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... Authors: Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. Deposit date: 2021-04-06 Release date: 2022-01-26 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7N6W	Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U2 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 Descriptor: 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhang, S, Wang, K, Mao, Y. Deposit date: 2021-06-09 Release date: 2021-09-22 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
7N6U	Structure of uncleaved HIV-1 JR-FL Env glycoprotein trimer in state U1 bound to small Molecule HIV-1 Entry Inhibitor BMS-378806 Descriptor: 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Zhang, S, Wang, K, Mao, Y. Deposit date: 2021-06-09 Release date: 2021-09-22 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer. J.Virol., 95, 2021
7MXE	Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ... Authors: Abernathy, M.E, Bjorkman, P.J. Deposit date: 2021-05-19 Release date: 2021-10-27 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Antibody elicited by HIV-1 immunogen vaccination in macaques displaces Env fusion peptide and destroys a neutralizing epitope. Npj Vaccines, 6, 2021
7N65	Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp41, ... Authors: Mangala Prasad, V, Shipley, M.M, Overbaugh, J.M, Lee, K.K. Deposit date: 2021-06-07 Release date: 2021-07-28 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (4.15 Å) Cite: Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection. Elife, 10, 2021
7MXD	Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 Env Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ... Authors: Zhou, T, Gao, F. Deposit date: 2021-05-19 Release date: 2022-03-30 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022
7N28	Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ... Authors: Zhou, T, Gao, F. Deposit date: 2021-05-28 Release date: 2022-04-06 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2. Adv Sci, 9, 2022
7L8F	BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-2 from animal Rh.33172 (Wk38 time point) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... Authors: Antanasijevic, A, Sewall, L.M, Ward, A.B. Deposit date: 2020-12-31 Release date: 2021-08-04 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.66 Å) Cite: Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nat Commun, 12, 2021
7LG6	BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... Authors: Cottrell, C.A, Torres, J.L, Wu, N.R, Ward, A.B. Deposit date: 2021-01-19 Release date: 2021-09-15 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.28 Å) Cite: Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. Cell Rep, 37, 2021
7LY9	Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2909 Heavy Chain, ... Authors: Gorman, J, Kwong, P.D. Deposit date: 2021-03-06 Release date: 2021-08-18 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.91 Å) Cite: Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces. Nat Commun, 12, 2021

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