7LDD
| native AMPA receptor | Descriptor: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | Authors: | Yu, J, Rao, P, Gouaux, E. | Deposit date: | 2021-01-13 | Release date: | 2021-05-12 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
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8DBI
| Human PRPS1 with Phosphate, ATP, and R5P; Hexamer | Descriptor: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hvorecny, K.L, Kollman, J.M. | Deposit date: | 2022-06-14 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Human PRPS1 filaments stabilize allosteric sites to regulate activity. Nat.Struct.Mol.Biol., 30, 2023
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7LDE
| native AMPA receptor | Descriptor: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | Authors: | Yu, J, Rao, P, Gouaux, E. | Deposit date: | 2021-01-13 | Release date: | 2021-05-12 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
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7LEP
| The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, DECANE, ... | Authors: | Yu, J, Rao, P, Gouaux, E. | Deposit date: | 2021-01-14 | Release date: | 2021-05-12 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
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7LJX
| Oxidized rat cytochrome c mutant (K53Q) | Descriptor: | Cytochrome c, somatic, HEME C, ... | Authors: | Huttemann, M, Edwards, B.F.P, Brunzelle, J.S, Vaishnav, A. | Deposit date: | 2021-02-01 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis. Cells, 10, 2021
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8CWO
| Cutibacterium acnes 30S ribosomal subunit with Sarecycline bound, body domain only in the local refined map | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | Deposit date: | 2022-05-19 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
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5BOZ
| Ricin A chain bound to camelid nanobody (VHH9)(E1) | Descriptor: | CHLORIDE ION, Ricin, SULFATE ION, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2015-05-27 | Release date: | 2016-12-07 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J. Biol. Chem., 292, 2017
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7WT7
| SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... | Authors: | Wang, X, Wang, L. | Deposit date: | 2022-02-04 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
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8DFU
| Cryo-EM structure of conjugation pili from Aeropyrum pernix | Descriptor: | (2S)-3-{[(3R,7S,11S,15S)-3,7,11,15,19-pentamethylicosyl]oxy}-2-{[(2R,6S,10S,14R)-2,6,10,14,18-pentamethylnonadecyl]oxy}propyl dihydrogen phosphate, Pilin protein | Authors: | Beltran, L.C, Egelman, E.H. | Deposit date: | 2022-06-22 | Release date: | 2023-03-22 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery. Nat Commun, 14, 2023
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7WT8
| SARS-CoV-2 Omicron variant spike in complex with Fab 9A8 (State 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 9A8, ... | Authors: | Wang, X, Wang, L. | Deposit date: | 2022-02-04 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A broader neutralizing antibody against all the current VOCs and VOIs targets unique epitope of SARS-CoV-2 RBD. Cell Discov, 8, 2022
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8CRX
| Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound | Descriptor: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | Deposit date: | 2022-05-12 | Release date: | 2023-03-22 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
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8DFT
| Cryo-EM structure of conjugative pili from Pyrobaculum calidifontis | Descriptor: | Pilin protein, [(2~{S},7~{S},11~{S},15~{S},19~{R},22~{R},26~{S},30~{R},34~{R},38~{S},43~{S},47~{S},51~{S},55~{R},58~{R},62~{S},66~{R},70~{R})-38-(hydroxymethyl)-7,11,15,19,22,26,30,34,43,47,51,55,58,62,66,70-hexadecamethyl-1,4,37,40-tetraoxacyclodoheptacont-2-yl]methanol | Authors: | Beltran, L.C, Egelman, E.H. | Deposit date: | 2022-06-22 | Release date: | 2023-03-22 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Archaeal DNA-import apparatus is homologous to bacterial conjugation machinery. Nat Commun, 14, 2023
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5V2C
| RE-REFINEMENT OF CRYSTAL STRUCTURE OF PHOTOSYSTEM II COMPLEX | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Wang, J, Wiwczar, J.M, Brudvig, G.W. | Deposit date: | 2017-03-03 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Chlorophyll a with a farnesyl tail in thermophilic cyanobacteria. Photosyn. Res., 134, 2017
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7LY9
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8CVM
| Cutibacterium acnes 50S ribosomal subunit with P-site tRNA and Sarecycline bound in the local refined map | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | Deposit date: | 2022-05-18 | Release date: | 2023-03-15 | Last modified: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism. Nucleic Acids Res., 51, 2023
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7WPE
| SARS-CoV-2 Omicron Variant S Trimer complexed with two JMB2002 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-Fab nanobody, ... | Authors: | Yin, W, Xu, Y, Xu, P, Cao, X, Wu, C, Gu, C, He, X, Wang, X, Huang, S, Yuan, Q, Wu, K, Hu, W, Huang, Z, Liu, J, Wang, Z, Jia, F, Xia, K, Liu, P, Wang, X, Song, B, Zheng, J, Jiang, H, Cheng, X, Jiang, Y, Deng, S.J, Xu, H.E. | Deposit date: | 2022-01-23 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody. Science, 375, 2022
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7LGU
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8DBA
| Crystal structure of dodecameric KaiC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC, MAGNESIUM ION | Authors: | Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. | Deposit date: | 2022-06-14 | Release date: | 2023-03-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | From primordial clocks to circadian oscillators. Nature, 616, 2023
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5V93
| Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J. | Deposit date: | 2017-03-22 | Release date: | 2017-09-20 | Last modified: | 2020-08-12 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res., 45, 2017
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5WIT
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with pikromycin and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution | Descriptor: | (3R,5R,6S,7S,9R,11E,13S,14R)-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-2,4,10-trioxo-1-oxacyclotetradec-11-en-6-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Almutairi, M.M, Svetlov, M.S, Hansen, D.A, Khabibullina, N.F, Klepacki, D, Kang, H.Y, Sherman, D.H, Vazquez-Laslop, N, Polikanov, Y.S, Mankin, A.S. | Deposit date: | 2017-07-20 | Release date: | 2018-02-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins. Nucleic Acids Res., 45, 2017
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7LGW
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5WRK
| Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | Descriptor: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | Authors: | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | Deposit date: | 2016-12-02 | Release date: | 2017-12-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling Elife, 7, 2018
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7W5Z
| Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ... | Authors: | Zhou, L, Maldonado, M, Padavannil, A, Letts, J. | Deposit date: | 2021-11-30 | Release date: | 2022-04-06 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
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7W85
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5WQ1
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