1K5R
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![BU of 1k5r by Molmil](/molmil-images/mine/1k5r) | YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant | Descriptor: | 65 KDA YES-ASSOCIATED PROTEIN, Fragment of WBP-1 | Authors: | Ferguson, N, Pires, J.R, Toepert, F, Johnson, C.M, Pan, Y.P, Volkmer-Engert, R, Schneider-Mergener, J, Daggett, V, Oschkinat, H, Fersht, A.R. | Deposit date: | 2001-10-12 | Release date: | 2001-11-02 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions. Proc.Natl.Acad.Sci.USA, 98, 2001
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3EUV
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![BU of 3euv by Molmil](/molmil-images/mine/3euv) | Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP | Descriptor: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | Authors: | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | Deposit date: | 2008-10-11 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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5T47
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![BU of 5t47 by Molmil](/molmil-images/mine/5t47) | Crystal structure of the D. melanogaster eIF4E-eIF4G complex | Descriptor: | Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ... | Authors: | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | Deposit date: | 2016-08-29 | Release date: | 2016-10-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation. Mol.Cell, 64, 2016
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8I7E
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![BU of 8i7e by Molmil](/molmil-images/mine/8i7e) | Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase | Authors: | Kumar, N, Dilawari, R, Chaubey, G.K, Modanwal, R, Talukdar, S, Dhiman, A, Chaudhary, S, Patidar, A, Kumar, A, Raje, C.I, Raje, M, Kumaran, S. | Deposit date: | 2023-01-31 | Release date: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A To Be Published
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3EU5
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![BU of 3eu5 by Molmil](/molmil-images/mine/3eu5) | Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP | Descriptor: | (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate, Protein farnesyltransferase subunit beta, Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, ... | Authors: | Guo, Z, Nguyen, U.T.T, Delon, C, Bon, R.S, Blankenfeldt, W, Goody, R.S, Waldmann, H, Wolters, D, Alexandrov, K. | Deposit date: | 2008-10-09 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analysis of the eukaryotic prenylome by isoprenoid affinity tagging Nat.Chem.Biol., 5, 2009
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2IS0
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![BU of 2is0 by Molmil](/molmil-images/mine/2is0) | Crystal structure of human Beta-secretase complexed with inhibitor | Descriptor: | (2S)-2-AMINO-2-BENZYL-3-HYDROXYPROPYL 3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZOATE, Beta-secretase 1 | Authors: | Munshi, S. | Deposit date: | 2006-10-16 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of oxadiazoyl tertiary carbinamine inhibitors of beta-secretase (BACE-1). J.Med.Chem., 49, 2006
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2IRZ
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![BU of 2irz by Molmil](/molmil-images/mine/2irz) | Crystal structure of human Beta-secretase complexed with inhibitor | Descriptor: | 3-{5-[(1R)-1-AMINO-1-METHYL-2-PHENYLETHYL]-1,3,4-OXADIAZOL-2-YL}-N-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE, Beta-secretase 1 | Authors: | Munshi, S. | Deposit date: | 2006-10-16 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of oxadiazoyl tertiary carbinamine inhibitors of beta-secretase (BACE-1). J.Med.Chem., 49, 2006
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5JHX
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![BU of 5jhx by Molmil](/molmil-images/mine/5jhx) | Crystal Structure of Fungal MagKatG2 at pH 3.0 | Descriptor: | CITRATE ANION, Catalase-peroxidase 2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Gasselhuber, B, Obinger, C, Carpena, X. | Deposit date: | 2016-04-21 | Release date: | 2016-06-22 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Interaction with the Redox Cofactor MYW and Functional Role of a Mobile Arginine in Eukaryotic Catalase-Peroxidase. Biochemistry, 55, 2016
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3M9A
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![BU of 3m9a by Molmil](/molmil-images/mine/3m9a) | Protein structure of type III plasmid segregation TubR | Descriptor: | Putative DNA-binding protein | Authors: | Schumacher, M.A, Ni, L. | Deposit date: | 2010-03-21 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
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3M8K
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![BU of 3m8k by Molmil](/molmil-images/mine/3m8k) | Protein structure of type III plasmid segregation TubZ | Descriptor: | FtsZ/tubulin-related protein | Authors: | Schumacher, M.A, Ni, L. | Deposit date: | 2010-03-18 | Release date: | 2010-07-07 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
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3M89
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![BU of 3m89 by Molmil](/molmil-images/mine/3m89) | Structure of TubZ-GTP-g-S | Descriptor: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, FtsZ/tubulin-related protein | Authors: | Ni, L, Xu, W, Schumacher, M.A. | Deposit date: | 2010-03-17 | Release date: | 2010-07-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
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3M8F
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![BU of 3m8f by Molmil](/molmil-images/mine/3m8f) | Protein structure of type III plasmid segregation TubR mutant | Descriptor: | Putative DNA-binding protein | Authors: | Schumacher, M.A, Ni, L. | Deposit date: | 2010-03-17 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
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5XES
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![BU of 5xes by Molmil](/molmil-images/mine/5xes) | TK9 NMR structure in SDS micelle | Descriptor: | THR-VAL-TYR-VAL-TYR-SER-ARG-VAL-LYS | Authors: | Ghosh, A, Bhunia, A. | Deposit date: | 2017-04-05 | Release date: | 2018-04-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insights of a self-assembling 9-residue peptide from the C-terminal tail of the SARS corona virus E-protein in DPC and SDS micelles: A combined high and low resolution spectroscopic study. Biochim Biophys Acta Biomembr, 1860, 2018
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3KMY
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![BU of 3kmy by Molmil](/molmil-images/mine/3kmy) | Structure of BACE bound to SCH12472 | Descriptor: | 3-[2-(3-chlorophenyl)ethyl]pyridin-2-amine, Beta-secretase 1 | Authors: | Strickland, C, Wang, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
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3NSH
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![BU of 3nsh by Molmil](/molmil-images/mine/3nsh) | BACE-1 in complex with ELN475957 | Descriptor: | Beta-secretase 1, N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide | Authors: | Probst, G.D, Bowers, S, Sealy, J.M, Brecht, E, Yao, N. | Deposit date: | 2010-07-01 | Release date: | 2010-09-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg.Med.Chem.Lett., 20, 2010
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1C02
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![BU of 1c02 by Molmil](/molmil-images/mine/1c02) | CRYSTAL STRUCTURE OF YEAST YPD1P | Descriptor: | PHOSPHOTRANSFERASE YPD1P | Authors: | Song, H.K, Lee, J.Y, Lee, M.G, Suh, S.W. | Deposit date: | 1999-07-14 | Release date: | 2000-01-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insights into eukaryotic multistep phosphorelay signal transduction revealed by the crystal structure of Ypd1p from Saccharomyces cerevisiae. J.Mol.Biol., 293, 1999
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8PSV
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![BU of 8psv by Molmil](/molmil-images/mine/8psv) | 2.7 A cryo-EM structure of in vitro assembled type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Hospenthal, M, Zyla, D, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-13 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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1H7X
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![BU of 1h7x by Molmil](/molmil-images/mine/1h7x) | Dihydropyrimidine dehydrogenase (DPD) from pig, ternary complex of a mutant enzyme (C671A), NADPH and 5-fluorouracil | Descriptor: | 5-FLUOROURACIL, DIHYDROPYRIMIDINE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ... | Authors: | Dobritzsch, D, Schneider, G, Schnackerz, K.D, Lindqvist, Y. | Deposit date: | 2001-01-19 | Release date: | 2001-02-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure of Dihydropyrimidine Dehydrogenase, a Major Determinant of the Pharmacokinetics of the Anti-Cancer Drug 5-Fluorouracil Embo J., 20, 2001
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1H53
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![BU of 1h53 by Molmil](/molmil-images/mine/1h53) | Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by X-ray Crystallography | Descriptor: | ANGIOGENIN, CITRIC ACID, PHOSPHATE ION | Authors: | Leonidas, D.D, Chavali, G.B, Jardine, A.M, Li, S, Shapiro, R, Acharya, K.R. | Deposit date: | 2001-05-18 | Release date: | 2001-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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8Q3Y
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![BU of 8q3y by Molmil](/molmil-images/mine/8q3y) | |
1H52
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![BU of 1h52 by Molmil](/molmil-images/mine/1h52) | Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by X-ray Crystallography | Descriptor: | ANGIOGENIN, PYROPHOSPHATE 2- | Authors: | Leonidas, D.D, Chavali, G.B, Jardine, A.M, Li, S, Shapiro, R, Acharya, K.R. | Deposit date: | 2001-05-18 | Release date: | 2001-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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8PTU
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![BU of 8ptu by Molmil](/molmil-images/mine/8ptu) | 2.5 A cryo-EM structure of the in vitro FimD-catalyzed assembly of type 1 pilus rod | Descriptor: | Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Hospenthal, M, Glockshuber, R, Waksman, G. | Deposit date: | 2023-07-14 | Release date: | 2024-04-10 | Last modified: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili. Nat Commun, 15, 2024
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7SP5
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![BU of 7sp5 by Molmil](/molmil-images/mine/7sp5) | Crystal Structure of a Eukaryotic Phosphate Transporter | Descriptor: | PHOSPHATE ION, Phosphate transporter, nonyl beta-D-glucopyranoside | Authors: | Stroud, R.M, Pedersen, B.P, Kumar, H, Waight, A.B, Risenmay, A.J, Roe-Zurz, Z, Chau, B.H, Schlessinger, A, Bonomi, M, Harries, W, Sali, A, Johri, A.K, Finer-Moore, J. | Deposit date: | 2021-11-02 | Release date: | 2021-11-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of a eukaryotic phosphate transporter. Nature, 496, 2013
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2LBF
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![BU of 2lbf by Molmil](/molmil-images/mine/2lbf) | Solution structure of the dimerization domain of human ribosomal protein P1/P2 heterodimer | Descriptor: | 60S acidic ribosomal protein P1, 60S acidic ribosomal protein P2 | Authors: | Lee, K.-M, Yu, C.W.-H, Chiu, T.Y.-H, Sze, K.-H, Shaw, P.-C, Wong, K.-B. | Deposit date: | 2011-03-30 | Release date: | 2011-12-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the dimerization domain of the eukaryotic stalk P1/P2 complex reveals the structural organization of eukaryotic stalk complex Nucleic Acids Res., 2011
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3S4D
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![BU of 3s4d by Molmil](/molmil-images/mine/3s4d) | Lactose phosphorylase in a ternary complex with cellobiose and sulfate | Descriptor: | Lactose Phosphorylase, SULFATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Van Hoorebeke, A, Stout, J, Soetaert, W, Van Beeumen, J, Desmet, T, Savvides, S. | Deposit date: | 2011-05-19 | Release date: | 2012-06-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Cellobiose phosphorylase: reconstructing the structural itinerary along the catalytic pathway To be Published
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