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7M1Q
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BU of 7m1q by Molmil
Human ABCA4 structure in complex with N-ret-PE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Retinal-specific phospholipid-transporting ATPase ABCA4, ...
Authors:Scortecci, J.F, Van Petegem, F, Molday, R.S.
Deposit date:2021-03-14
Release date:2021-09-08
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease.
Nat Commun, 12, 2021
1IY5
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BU of 1iy5 by Molmil
Solution structure of wild type OMSVP3
Descriptor: OMSVP3
Authors:Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y.
Deposit date:2002-07-23
Release date:2003-03-11
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
1IY6
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BU of 1iy6 by Molmil
Solution structure of OMSVP3 variant, P14C/N39C
Descriptor: OMSVP3
Authors:Hemmi, H, Kumazaki, T, Yamazaki, T, Kojima, S, Yoshida, T, Kyogoku, Y, Katsu, M, Yokosawa, H, Miura, K, Kobayashi, Y.
Deposit date:2002-07-23
Release date:2003-03-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Inhibitory Specificity Change of Ovomucoid Third Domain of the Silver Pheasant upon Introduction of an Engineered Cys14-Cys39 Bond
BIOCHEMISTRY, 42, 2003
5TSW
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BU of 5tsw by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
Descriptor: PROTEIN (TUMOR NECROSIS FACTOR-ALPHA)
Authors:Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H.
Deposit date:1999-04-22
Release date:1999-05-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
J.Biol.Chem., 273, 1998
5VAV
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BU of 5vav by Molmil
Design of a novel cyclic peptide that alleviates symptoms in a murine model of inflammatory bowel disease
Descriptor: cyc-MC12
Authors:Daly, N.L, Cobos Caceres, C.
Deposit date:2017-03-28
Release date:2017-05-10
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease.
J. Biol. Chem., 292, 2017
5VFW
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BU of 5vfw by Molmil
An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease
Descriptor: Annexin A1
Authors:Daly, N.L, Cobos Caceres, C.
Deposit date:2017-04-09
Release date:2017-05-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease.
J. Biol. Chem., 292, 2017
7KUS
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BU of 7kus by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N8-Acetylspermidine (Tetrahedral Intermediate)
Descriptor: 1,2-ETHANEDIOL, 1-({4-[(3-aminopropyl)amino]butyl}amino)ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
6CDX
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BU of 6cdx by Molmil
High-resolution crystal structure of fluoropropylated cystine knot, binding to alpha-5 beta-6 integrin
Descriptor: cystine knot (fluoropropylated)
Authors:Kimura, R, Nix, J, Bongura, C, Chakraborti, S, Gambhir, S, Filipp, F.V.
Deposit date:2018-02-09
Release date:2019-08-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1 Å)
Cite:Evaluation of integrin alpha v beta6cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.
Nat Commun, 10, 2019
7KUQ
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BU of 7kuq by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 Y307F Mutant in Complex with N8-Acetylspermidine
Descriptor: N-{4-[(3-aminopropyl)amino]butyl}acetamide, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
7KUR
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BU of 7kur by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 Y307F Mutant in Complex with N-Acetylputrescine
Descriptor: DI(HYDROXYETHYL)ETHER, N-(4-aminobutyl)acetamide, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
7KUT
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BU of 7kut by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 H137A Mutant in Complex with N-Acetylputrescine (Tetrahedral Intermediate)
Descriptor: 1,2-ETHANEDIOL, 1-[(4-aminobutyl)amino]ethane-1,1-diol, DI(HYDROXYETHYL)ETHER, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
7KUV
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BU of 7kuv by Molmil
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Acetate
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ...
Authors:Herbst-Gervasoni, C.J, Christianson, D.W.
Deposit date:2020-11-25
Release date:2021-02-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:X-ray Crystallographic Snapshots of Substrate Binding in the Active Site of Histone Deacetylase 10.
Biochemistry, 60, 2021
5U87
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BU of 5u87 by Molmil
NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin
Descriptor: Preproalbumin PawS1
Authors:Franke, B, James, A.M, Mobli, M, Colgrave, M.L, Mylne, J.S, Rosengren, K.J.
Deposit date:2016-12-14
Release date:2017-03-01
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin
to be published
7VOO
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BU of 7voo by Molmil
Induced alpha-2-macroglobulin monomer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ...
Authors:Huang, X, Wang, Y, Ping, Z.
Deposit date:2021-10-14
Release date:2022-10-19
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
7VON
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BU of 7von by Molmil
Native alpha-2-macroglobulin monomer
Descriptor: Alpha-2-macroglobulin
Authors:Huang, X, Wang, Y.
Deposit date:2021-10-14
Release date:2022-11-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.
Sci China Life Sci, 65, 2022
8KF4
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BU of 8kf4 by Molmil
The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient.
Descriptor: Amyloid-beta precursor protein
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-15
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient.
To Be Published
8KEW
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BU of 8kew by Molmil
The cryo-EM structure of type1 amyloid beta 42 fibril.
Descriptor: P3(40)
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-13
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The cryo-EM structure of type1 amyloid beta 42 fibril.
To Be Published
8KF1
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BU of 8kf1 by Molmil
The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril.
Descriptor: 4-[2-[6-[2-[2-(2-fluoranylethoxy)ethoxy]ethoxy]pyridin-3-yl]ethyl]-~{N}-methyl-aniline, P3(40)
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-15
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril.
To Be Published
8KF5
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BU of 8kf5 by Molmil
The cryo-EM structure of type1 amyloid beta 42 fibril in AD3.
Descriptor: Amyloid-beta precursor protein
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-15
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The cryo-EM structure of type1 amyloid beta 42 fibril in AD3.
To Be Published
8KF3
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BU of 8kf3 by Molmil
The cryo-EM structure of type3 amyloid beta 42 fibril.
Descriptor: Amyloid-beta precursor protein
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-15
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The cryo-EM structure of type1 amyloid beta 42 fibril.
To Be Published
8KF6
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BU of 8kf6 by Molmil
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.
Descriptor: P3(40)
Authors:Zhao, Q.Y, Tao, Y.Q, Liu, C, Li, D.
Deposit date:2023-08-15
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The cryo-EM structure of type1 amyloid beta 42 fibril.
To Be Published
8P4K
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BU of 8p4k by Molmil
Vaccinia Virus palisade layer A10 trimer
Descriptor: Core protein OPG136
Authors:Datler, J, Hansen, J.M, Thader, A, Schloegl, A, Hodirnau, V.V, Schur, F.K.M.
Deposit date:2023-05-22
Release date:2024-01-17
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores.
Nat.Struct.Mol.Biol., 31, 2024
8OVB
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BU of 8ovb by Molmil
Human Complement C3b in complex with Trypanosoma brucei ISG65.
Descriptor: Complement C3, Complement C3f fragment, ISG65 G
Authors:Cook, A.D, Higgins, M.K.
Deposit date:2023-04-25
Release date:2024-02-14
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular mechanism of complement inhibition by the trypanosome receptor ISG65.
Elife, 12, 2024
8OTF
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BU of 8otf by Molmil
Ab typeII filament from Guam ALS/PDC
Descriptor: Amyloid-beta precursor protein
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8PE9
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BU of 8pe9 by Molmil
Complex between DDR1 DS-like domain and PRTH-101 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N.
Deposit date:2023-06-13
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.152 Å)
Cite:A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer.
J Immunother Cancer, 11, 2023

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PDB entries from 2024-11-06

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