7VOO

Induced alpha-2-macroglobulin monomer

Summary for 7VOO

• Entry DOI: 10.2210/pdb7voo/pdb
• EMDB information: 32052
• Descriptor: Alpha-2-macroglobulin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: protease inhibitor, blood clotting
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 147766.67

Authors

Huang, X.,Wang, Y.,Ping, Z. (deposition date: 2021-10-14, release date: 2022-10-19, Last modification date: 2022-12-07)

• Primary citation: Huang, X.,Wang, Y.,Yu, C.,Zhang, H.,Ru, Q.,Li, X.,Song, K.,Zhou, M.,Zhu, P.; Cryo-EM structures reveal the dynamic transformation of human alpha-2-macroglobulin working as a protease inhibitor.; Sci China Life Sci, 65:2491-2504, 2022; PubMed: 35781771; DOI: 10.1007/s11427-022-2139-2

Experimental method

ELECTRON MICROSCOPY (3.9 Å)