3CXD
 
 | | Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide | | Descriptor: | Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, Light chain, ... | | Authors: | Du, J, Yang, H, Zhong, C, Ding, J. | | Deposit date: | 2008-04-24 | | Release date: | 2008-10-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis
J.Mol.Biol., 382, 2008
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3MJ9
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3D69
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1IT9
 | | CRYSTAL STRUCTURE OF AN ANTIGEN-BINDING FRAGMENT FROM A HUMANIZED VERSION OF THE ANTI-HUMAN FAS ANTIBODY HFE7A | | Descriptor: | HUMANIZED ANTIBODY HFE7A, HEAVY CHAIN, LIGHT CHAIN | | Authors: | Ito, S, Takayama, T, Hanzawa, H, Takahashi, T, Miyadai, K, Serizawa, N, Hata, T, Haruyama, H. | | Deposit date: | 2002-01-11 | | Release date: | 2003-02-25 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Humanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment
BIOL.PHARM.BULL., 25, 2002
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3ETB
 | | Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4 | | Descriptor: | Anthrax Protective Antigen, Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker | | Authors: | Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D. | | Deposit date: | 2008-10-07 | | Release date: | 2009-04-28 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
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1B2W
 | | COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | | Descriptor: | PROTEIN (ANTIBODY (HEAVY CHAIN)), PROTEIN (ANTIBODY (LIGHT CHAIN)) | | Authors: | Fan, Z, Shan, L, Goldsteen, B.Z, Guddat, L.W, Thakur, A, Landolfi, N.F, Co, M.S, Vasquez, M, Queen, C, Ramsland, P.A, Edmundson, A.B. | | Deposit date: | 1998-12-01 | | Release date: | 1999-05-06 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
J.Mol.Recog., 12, 1999
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3I50
 | | Crystal structure of the West Nile Virus envelope glycoprotein in complex with the E53 antibody Fab | | Descriptor: | Envelope glycoprotein, murine heavy chain (IgG3) of E53 monoclonal antibody Fab, murine kappa light chain of E53 monoclonal antibody Fab | | Authors: | Nybakken, G.E, Warren, J.T, Chen, B.R, Nelson, C.A, Fremont, D.H. | | Deposit date: | 2009-07-03 | | Release date: | 2009-10-27 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.
Embo J., 28, 2009
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4GAY
 | | Structure of the broadly neutralizing antibody AP33 | | Descriptor: | NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN, TRIETHYLENE GLYCOL | | Authors: | Potter, J.A, Owsianka, A, Jeffery, N, Matthews, D, Keck, Z, Lau, P, Foung, S.K.H, Taylor, G.L, Patel, A.H. | | Deposit date: | 2012-07-26 | | Release date: | 2012-10-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.
J.Virol., 86, 2012
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1CZ8
 | | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY | | Descriptor: | HEAVY CHAIN OF NEUTRALIZING ANTIBODY, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, SULFATE ION, ... | | Authors: | Chen, Y, Wiesmann, C, Fuh, G, Li, B, Christinger, H.W, McKay, P, de Vos, A.M, Lowman, H.B. | | Deposit date: | 1999-09-01 | | Release date: | 2000-03-20 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
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4GAJ
 | | Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 411-424) | | Descriptor: | Genome polyprotein, NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, NEUTRALIZING ANTIBODY AP33 LIGHT CHAIN | | Authors: | Potter, J.A, Owsianka, A, Taylor, G.L, Patel, A.H. | | Deposit date: | 2012-07-25 | | Release date: | 2012-10-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.
J.Virol., 86, 2012
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3J3Z
 | | Structure of MA28-7 neutralizing antibody Fab fragment from electron cryo-microscopy of enterovirus 71 complexed with a Fab fragment | | Descriptor: | MA28-7 neutralizing antibody heavy chain, MA28-7 neutralizing antibody light chain | | Authors: | Lee, H, Cifuente, J.O, Ashley, R.E, Conway, J.F, Makhov, A.M, Tano, Y, Shimizu, H, Nishimura, Y, Hafenstein, S. | | Deposit date: | 2013-05-21 | | Release date: | 2013-08-28 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (23.4 Å) | | Cite: | A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.
J.Virol., 87, 2013
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2GHW
 | | Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R | | Descriptor: | CHLORIDE ION, Spike glycoprotein, anti-sars scFv antibody, ... | | Authors: | Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C. | | Deposit date: | 2006-03-27 | | Release date: | 2006-09-19 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
J.Biol.Chem., 281, 2006
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3K2U
 | | Crystal structure of HGFA in complex with the allosteric inhibitory antibody Fab40 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Fab fragment, ... | | Authors: | Ganesan, R, Eigenbrot, C, Shia, S. | | Deposit date: | 2009-09-30 | | Release date: | 2009-12-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Unraveling the allosteric mechanism of serine protease inhibition by an antibody.
Structure, 17, 2009
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4GAG
 | | Structure of the broadly neutralizing antibody AP33 in complex with its HCV epitope (E2 residues 412-423) | | Descriptor: | GLYCEROL, Genome polyprotein, NEUTRALIZING ANTIBODY AP33 HEAVY CHAIN, ... | | Authors: | Potter, J.A, Owsianka, A, Angus, A.G.N, Jeffery, N, Matthews, D, Keck, Z, Lau, P, Foung, S.K.H, Taylor, G.L, Patel, A.H. | | Deposit date: | 2012-07-25 | | Release date: | 2012-10-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody.
J.Virol., 86, 2012
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1F3D
 | | CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN. | | Descriptor: | 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM, CATALYTIC ANTIBODY 4B2, SULFATE ION | | Authors: | Golinelli-Pimpaneau, B, Goncalves, O, Dintinger, T, Blanchard, D, Knossow, M, Tellier, C. | | Deposit date: | 2000-06-02 | | Release date: | 2000-09-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural evidence for a programmed general base in the active site of a catalytic antibody.
Proc.Natl.Acad.Sci.USA, 97, 2000
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1F3R
 | | COMPLEX BETWEEN FV ANTIBODY FRAGMENT AND AN ANALOGUE OF THE MAIN IMMUNOGENIC REGION OF THE ACETYLCHOLINE RECEPTOR | | Descriptor: | ACETYLCHOLINE RECEPTOR ALPHA, FV ANTIBODY FRAGMENT | | Authors: | Kleinjung, J, Petit, M.-C, Orlewski, P, Mamalaki, A, Tzartos, S.-J, Tsikaris, V, Sakarellos-Daitsiotis, M, Sakarellos, C, Marraud, M, Cung, M.-T. | | Deposit date: | 2000-06-06 | | Release date: | 2000-06-15 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach.
Biopolymers, 53, 2000
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3JAU
 | | The cryoEM map of EV71 mature viron in complex with the Fab fragment of antibody D5 | | Descriptor: | Capsid protein VP1, Heavy chain of Fab fragment variable region of antibody D5, Light chain of Fab fragment variable region of antibody D5 | | Authors: | Fan, C, Ye, X.H, Ku, Z.Q, Zuo, T, Kong, L.L, Zhang, C, Shi, J.P, Liu, Q.W, Chen, T, Zhang, Y.Y, Jiang, W, Zhang, L.Q, Huang, Z, Cong, Y. | | Deposit date: | 2015-06-24 | | Release date: | 2016-02-10 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody
Plos Pathog., 12, 2016
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4DVB
 | | The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | | Deposit date: | 2012-02-23 | | Release date: | 2013-01-16 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody.
Biochem.J., 449, 2013
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2VYR
 | | Structure of human MDM4 N-terminal domain bound to a single domain antibody | | Descriptor: | HUMAN SINGLE DOMAIN ANTIBODY, MDM4 PROTEIN, SULFATE ION | | Authors: | Yu, G.W, Vaysburd, M, Allen, M.D, Settanni, G, Fersht, A.R. | | Deposit date: | 2008-07-28 | | Release date: | 2008-11-25 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Human Mdm4 N-Terminal Domain Bound to a Single-Domain Antibody.
J.Mol.Biol., 385, 2009
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2Z91
 | | Crystal structure of the Fab fragment of anti-ciguatoxin antibody 10C9 | | Descriptor: | Anti-ciguatoxin antibody 10C9 FAB heavy chain, Anti-ciguatoxin antibody 10C9 FAB light chain | | Authors: | Ui, M, Tanaka, Y, Tsumoto, K. | | Deposit date: | 2007-09-14 | | Release date: | 2008-05-06 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9
J.Biol.Chem., 283, 2008
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2Z93
 | | Crystal structure of Fab fragment of anti-ciguatoxin antibody 10C9 in complex with CTX3C-ABCD | | Descriptor: | 1,6:5,9:8,12:11,16-TETRAANHYDRO-2,3,4,10,13,14-HEXADEOXY-D-GLYCERO-D-ALLO-D-GULO-HEPTADECA-2,13-DIENITOL, Anti-ciguatoxin antibody 10C9 Fab heavy chain, Anti-ciguatoxin antibody 10C9 Fab light chain | | Authors: | Ui, M, Tanaka, Y, Tsumoto, K. | | Deposit date: | 2007-09-14 | | Release date: | 2008-05-06 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | How Protein Recognizes Ladder-like Polycyclic Ethers: INTERACTIONS BETWEEN CIGUATOXIN (CTX3C) FRAGMENTS AND ITS SPECIFIC ANTIBODY 10C9
J.Biol.Chem., 283, 2008
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3QCT
 | | Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment | | Descriptor: | LT3015 antibody Fab fragment, heavy chain, light chain, ... | | Authors: | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | | Deposit date: | 2011-01-17 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1493 Å) | | Cite: | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
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3QCU
 | | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) | | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ... | | Authors: | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | | Deposit date: | 2011-01-17 | | Release date: | 2011-03-30 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.979 Å) | | Cite: | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
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4R4H
 | | Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ... | | Authors: | Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D. | | Deposit date: | 2014-08-19 | | Release date: | 2014-09-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (4.28 Å) | | Cite: | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
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4R4N
 | | Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... | | Authors: | Acharya, P, Louder, R, Kwong, P.D. | | Deposit date: | 2014-08-19 | | Release date: | 2014-11-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.56 Å) | | Cite: | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
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