3IOH
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![BU of 3ioh by Molmil](/molmil-images/mine/3ioh) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) | Descriptor: | GLYCEROL, Histo-blood group ABO system transferase | Authors: | Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. | Deposit date: | 2009-08-14 | Release date: | 2010-04-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat.Chem.Biol., 6, 2010
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2XGP
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![BU of 2xgp by Molmil](/molmil-images/mine/2xgp) | Yeast DNA polymerase eta in complex with C8-2-acetylaminofluorene containing DNA | Descriptor: | 5'-D(*CP*8FG*CP*TP*CP*AP*TP*CP*CP*AP*C)-3', 5'-D(*GP*TP*GP*GP*AP*TP*GP*AP*G)-3', CALCIUM ION, ... | Authors: | Scheider, S, Lammens, K, Schorr, S, Hopfner, K.P, Carell, T. | Deposit date: | 2010-06-07 | Release date: | 2010-11-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts. Proc.Natl.Acad.Sci.USA, 107, 2010
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2IVB
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![BU of 2ivb by Molmil](/molmil-images/mine/2ivb) | SITE DIRECTED MUTAGENESIS OF KEY RESIDUES INVOLVED IN THE CATALYTIC MECHANISM OF CYANASE | Descriptor: | AZIDE ION, CHLORIDE ION, CYANATE HYDRATASE, ... | Authors: | Guilloton, M, Walsh, M.A, Joachimiak, A, Anderson, P.M. | Deposit date: | 2006-06-09 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | A Twin Set of Low Pka Arginines Ensures the Concerted Acid Base Catalytic Mechanism of Cyanase To be Published
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5M61
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![BU of 5m61 by Molmil](/molmil-images/mine/5m61) | |
2XGC
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![BU of 2xgc by Molmil](/molmil-images/mine/2xgc) | Crystal structure of a designed heterodimeric variant T-A(I)B of the tetracycline repressor | Descriptor: | TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | Authors: | Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer. J.Mol.Biol., 403, 2010
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7U1Z
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![BU of 7u1z by Molmil](/molmil-images/mine/7u1z) | Crystal structure of the DRBD and CROPs of TcdA | Descriptor: | SULFATE ION, Toxin A | Authors: | Baohua, C, Peng, C, Kay, P, Rongsheng, J. | Deposit date: | 2022-02-22 | Release date: | 2022-03-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.18 Å) | Cite: | Structure and conformational dynamics of Clostridioides difficile toxin A. Life Sci Alliance, 5, 2022
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3IW0
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![BU of 3iw0 by Molmil](/molmil-images/mine/3iw0) | Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, C2221 crystal form | Descriptor: | Cytochrome P450 CYP125, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE | Authors: | McLean, K.J, Levy, C, Munro, A.W, Leys, D. | Deposit date: | 2009-09-02 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J.Biol.Chem., 284, 2009
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2IVQ
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![BU of 2ivq by Molmil](/molmil-images/mine/2ivq) | |
5MAT
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![BU of 5mat by Molmil](/molmil-images/mine/5mat) | Structure of human Sirtuin 2 in complex with a selective thienopyrimidinone based inhibitor | Descriptor: | (7~{R})-7-[(3,5-dimethyl-1,2-oxazol-4-yl)methylamino]-3-[(4-methoxynaphthalen-1-yl)methyl]-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one, HEXAETHYLENE GLYCOL, NAD-dependent protein deacetylase sirtuin-2, ... | Authors: | Moniot, S, Steegborn, C. | Deposit date: | 2016-11-04 | Release date: | 2017-02-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.069 Å) | Cite: | Thienopyrimidinone Based Sirtuin-2 (SIRT2)-Selective Inhibitors Bind in the Ligand Induced Selectivity Pocket. J. Med. Chem., 60, 2017
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3INK
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![BU of 3ink by Molmil](/molmil-images/mine/3ink) | |
7BST
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![BU of 7bst by Molmil](/molmil-images/mine/7bst) | EcoR124I-Ocr in the Intermediate State | Descriptor: | Overcome classical restriction gp0.3, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | Authors: | Gao, Y, Gao, P. | Deposit date: | 2020-03-31 | Release date: | 2020-05-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.37 Å) | Cite: | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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3ICB
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![BU of 3icb by Molmil](/molmil-images/mine/3icb) | THE REFINED STRUCTURE OF VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN FROM BOVINE INTESTINE. MOLECULAR DETAILS, ION BINDING, AND IMPLICATIONS FOR THE STRUCTURE OF OTHER CALCIUM-BINDING PROTEINS | Descriptor: | CALCIUM ION, CALCIUM-BINDING PROTEIN, SULFATE ION | Authors: | Szebenyi, D.M.E, Moffat, K. | Deposit date: | 1986-09-09 | Release date: | 1986-10-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins. J.Biol.Chem., 261, 1986
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2XDP
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![BU of 2xdp by Molmil](/molmil-images/mine/2xdp) | Crystal structure of the tudor domain of human JMJD2C | Descriptor: | LYSINE-SPECIFIC DEMETHYLASE 4C, SULFATE ION | Authors: | Yue, W.W, Gileadi, C, Krojer, T, Weisbach, H, Ugochukwu, E, Daniel, M, Phillips, C, Chaikuad, A, von Delft, F, Allerston, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | Deposit date: | 2010-05-06 | Release date: | 2010-06-09 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Crystal Structure of the Tudor Domain of Human Jmjd2C To be Published
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8PQX
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![BU of 8pqx by Molmil](/molmil-images/mine/8pqx) | p97 (VCP) mutant - F539A state III | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transitional endoplasmic reticulum ATPase | Authors: | Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A. | Deposit date: | 2023-07-12 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | p97 (VCP) mutant - F539A state III To Be Published
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7JR4
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![BU of 7jr4 by Molmil](/molmil-images/mine/7jr4) | |
7TQV
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![BU of 7tqv by Molmil](/molmil-images/mine/7tqv) | SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA | Descriptor: | RNA (33-MER), Uridylate-specific endoribonuclease | Authors: | Frazier, M.N, Krahn, J.M, Butay, K.J, Dillard, L.B, Borgnia, M.J, Stanley, R.E. | Deposit date: | 2022-01-27 | Release date: | 2022-03-23 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease. Nucleic Acids Res., 50, 2022
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7JSH
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![BU of 7jsh by Molmil](/molmil-images/mine/7jsh) | Adeno-Associated Virus 2 Rep68 HD Heptamer-ssAAVS1 with ATPgS | Descriptor: | DNA (5'-D(P*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*CP*TP*CP*GP*C)-3'), Protein Rep68 | Authors: | Escalante, C.R. | Deposit date: | 2020-08-14 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA+ machine that can switch between oligomeric states. Nucleic Acids Res., 48, 2020
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3J40
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![BU of 3j40 by Molmil](/molmil-images/mine/3j40) | Validated Near-Atomic Resolution Structure of Bacteriophage Epsilon15 Derived from Cryo-EM and Modeling | Descriptor: | gp10, gp7 | Authors: | Baker, M.L, Hryc, C.F, Zhang, Q, Wu, W, Jakana, J, Haase-Pettingell, C, Afonine, P.V, Adams, P.D, King, J.A, Jiang, W, Chiu, W. | Deposit date: | 2013-05-30 | Release date: | 2013-07-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling. Proc.Natl.Acad.Sci.USA, 110, 2013
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7BOM
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![BU of 7bom by Molmil](/molmil-images/mine/7bom) | Crystal structure of recombinant horse spleen apo-R52C/E56C/R59C/E63C-Fr immobilized with gold ions. | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ... | Authors: | Hishikawa, Y, Maity, B, Ito, N, Abe, S, Lu, D, Ueno, T. | Deposit date: | 2020-03-19 | Release date: | 2021-01-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Design of Multinuclear Gold Binding Site at the Two-fold Symmetric Interface of the Ferritin Cage Chem Lett., 49, 2021
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3J1X
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![BU of 3j1x by Molmil](/molmil-images/mine/3j1x) | A refined model of the prototypical Salmonella typhimurium T3SS basal body reveals the molecular basis for its assembly | Descriptor: | Protein PrgH | Authors: | Sgourakis, N.G, Bergeron, J.R.C, Worrall, L.J, Strynadka, N.C.J, Baker, D. | Deposit date: | 2012-07-10 | Release date: | 2013-05-22 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.7 Å) | Cite: | A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. Plos Pathog., 9, 2013
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2XNN
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![BU of 2xnn by Molmil](/molmil-images/mine/2xnn) | Structure of Nek2 bound to CCT242430 | Descriptor: | 1,2-ETHANEDIOL, 5-(1H-benzimidazol-1-yl)-3-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide, CHLORIDE ION, ... | Authors: | Mas-Droux, C, Bayliss, R. | Deposit date: | 2010-08-05 | Release date: | 2011-03-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J.Med.Chem., 54, 2011
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2MR3
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![BU of 2mr3 by Molmil](/molmil-images/mine/2mr3) | A subunit of 26S proteasome lid complex | Descriptor: | 26S proteasome regulatory subunit RPN9 | Authors: | Wu, Y, Hu, Y, Jin, C. | Deposit date: | 2014-06-30 | Release date: | 2015-02-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of yeast Rpn9: insights into proteasome lid assembly. J. Biol. Chem., 290, 2015
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2MUZ
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![BU of 2muz by Molmil](/molmil-images/mine/2muz) | ssNMR structure of a designed rocker protein | Descriptor: | designed rocker protein | Authors: | Wang, T, Joh, N, Wu, Y, DeGrado, W.F, Hong, M. | Deposit date: | 2014-09-18 | Release date: | 2014-12-24 | Last modified: | 2015-01-14 | Method: | SOLUTION NMR | Cite: | De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
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7BOV
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![BU of 7bov by Molmil](/molmil-images/mine/7bov) | The Structure of Bacillus subtilis glycosyltransferase,Bs-YjiC | Descriptor: | GLYCEROL, SODIUM ION, Uncharacterized UDP-glucosyltransferase YjiC | Authors: | Zhao, C, Liu, B, Zhao, N.L, Luo, Y.Z, Bao, R. | Deposit date: | 2020-03-20 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis. Int.J.Biol.Macromol., 166, 2021
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7JN4
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![BU of 7jn4 by Molmil](/molmil-images/mine/7jn4) | Rubisco in the apo state | Descriptor: | Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, chloroplastic | Authors: | Matthies, D, Jonikas, M.C, He, S. | Deposit date: | 2020-08-03 | Release date: | 2020-11-18 | Last modified: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (2.68 Å) | Cite: | The structural basis of Rubisco phase separation in the pyrenoid. Nat.Plants, 6, 2020
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