3IW0
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125, C2221 crystal form
Summary for 3IW0
| Entry DOI | 10.2210/pdb3iw0/pdb |
| Related | 2IW1 2IW2 3IVY |
| Descriptor | Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | cholesterol, cytochrome p450, monooxygenase, tuberculosis, heme, iron, metal-binding, oxidoreductase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 49202.95 |
| Authors | McLean, K.J.,Levy, C.,Munro, A.W.,Leys, D. (deposition date: 2009-09-02, release date: 2009-11-03, Last modification date: 2023-09-06) |
| Primary citation | McLean, K.J.,Lafite, P.,Levy, C.,Cheesman, M.R.,Mast, N.,Pikuleva, I.A.,Leys, D.,Munro, A.W. The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection. J.Biol.Chem., 284:35524-35533, 2009 Cited by PubMed: 19846552DOI: 10.1074/jbc.M109.032706 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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