7TQV

SARS-CoV-2 endoribonuclease Nsp15 bound to dsRNA

Summary for 7TQV

Entry DOI	10.2210/pdb7tqv/pdb
EMDB information	25915 26073
Descriptor	Uridylate-specific endoribonuclease, RNA (33-MER) (3 entities in total)
Functional Keywords	endoribonuclease, viral protein, viral protein-rna complex, viral protein/rna
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	8
Total formula weight	277493.41
Authors	Frazier, M.N.,Krahn, J.M.,Butay, K.J.,Dillard, L.B.,Borgnia, M.J.,Stanley, R.E. (deposition date: 2022-01-27, release date: 2022-03-23, Last modification date: 2022-12-07)
Primary citation	Frazier, M.N.,Wilson, I.M.,Krahn, J.M.,Butay, K.J.,Dillard, L.B.,Borgnia, M.J.,Stanley, R.E. Flipped over U: structural basis for dsRNA cleavage by the SARS-CoV-2 endoribonuclease. Nucleic Acids Res., 50:8290-8301, 2022 Cited by PubMed: 35801916 DOI: 10.1093/nar/gkac589 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.43 Å)

Structure validation