7TOQ
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![BU of 7toq by Molmil](/molmil-images/mine/7toq) | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7ZSB
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7TPT
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![BU of 7tpt by Molmil](/molmil-images/mine/7tpt) | Single-particle Cryo-EM structure of Arp2/3 complex at branched-actin junction. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Ding, B, Narvaez-Ortiz, H.Y, Nolen, B.J, Chowdhury, S. | Deposit date: | 2022-01-26 | Release date: | 2022-05-25 | Last modified: | 2022-06-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy. Proc.Natl.Acad.Sci.USA, 119, 2022
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7ZSA
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7TXU
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![BU of 7txu by Molmil](/molmil-images/mine/7txu) | Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 with ATP and 16x(Asp-Arg) | Descriptor: | 16x(Asp-Arg), ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase, ... | Authors: | Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. | Deposit date: | 2022-02-09 | Release date: | 2022-06-01 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | A cryptic third active site in cyanophycin synthetase creates primers for polymerization Nat Commun, 13, 2022
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7TOO
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![BU of 7too by Molmil](/molmil-images/mine/7too) | Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | Deposit date: | 2022-01-24 | Release date: | 2022-05-25 | Last modified: | 2022-06-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7TXV
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![BU of 7txv by Molmil](/molmil-images/mine/7txv) | Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 E82Q with ATP and 16x(Asp-Arg) | Descriptor: | 16x(Asp-Arg), ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase, ... | Authors: | Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. | Deposit date: | 2022-02-09 | Release date: | 2022-06-01 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A cryptic third active site in cyanophycin synthetase creates primers for polymerization Nat Commun, 13, 2022
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6WP4
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![BU of 6wp4 by Molmil](/molmil-images/mine/6wp4) | Pyruvate Kinase M2 mutant-S37E | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Nandi, S, Razzaghi, M, Srivastava, D, Dey, M. | Deposit date: | 2020-04-26 | Release date: | 2020-09-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation. J.Biol.Chem., 295, 2020
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7ZQ9
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![BU of 7zq9 by Molmil](/molmil-images/mine/7zq9) | Dimeric PSI of Chlamydomonas reinhardtii at 2.74 A resolution (symmetry expanded) | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Naschberger, A, Amunts, A. | Deposit date: | 2022-04-29 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex. Nat.Plants, 8, 2022
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8A22
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![BU of 8a22 by Molmil](/molmil-images/mine/8a22) | Structure of the mitochondrial ribosome from Polytomella magna | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Tobiasson, V, Berzina, I, Amunts, A. | Deposit date: | 2022-06-02 | Release date: | 2022-11-16 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements. Nat Commun, 13, 2022
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7ZS9
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7TNQ
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![BU of 7tnq by Molmil](/molmil-images/mine/7tnq) | The symmetry-released subpellicular microtubule map from detergent-extracted Toxoplasma cells | Descriptor: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | Authors: | Sun, S.Y, Pintilie, G.D, Chen, M. | Deposit date: | 2022-01-21 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TNS
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![BU of 7tns by Molmil](/molmil-images/mine/7tns) | Subpellicular microtubule from detergent-extract Toxoplasma gondii cells | Descriptor: | Microtubule associated protein SPM1, PDI family protein, Tubulin alpha chain, ... | Authors: | Sun, S.Y, Pintilie, G.D, Chen, M, Chiu, W. | Deposit date: | 2022-01-21 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TXH
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![BU of 7txh by Molmil](/molmil-images/mine/7txh) | Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca | Descriptor: | GLYCEROL, Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, ... | Authors: | Hauseman, Z.J, Viscomi, J, Dhembi, A, Clark, K, King, D.A, Fodor, M. | Deposit date: | 2022-02-09 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the MRAS-SHOC2-PP1C phosphatase complex. Nature, 609, 2022
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6WYD
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![BU of 6wyd by Molmil](/molmil-images/mine/6wyd) | CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-12 (AKA; 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyrid | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, CALCIUM ION, ... | Authors: | Khan, J.A. | Deposit date: | 2020-05-12 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg.Med.Chem., 28, 2020
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6WEF
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7ZQC
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![BU of 7zqc by Molmil](/molmil-images/mine/7zqc) | Monomeric PSI of Chlamydomonas reinhardtii at 2.31 A resolution | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Naschberger, A, Amunts, A. | Deposit date: | 2022-04-29 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.31 Å) | Cite: | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex. Nat.Plants, 8, 2022
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7ZQD
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![BU of 7zqd by Molmil](/molmil-images/mine/7zqd) | Dimeric PSI of Chlamydomonas reinhardtii at 2.97 A resolution | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Naschberger, A, Amunts, A. | Deposit date: | 2022-04-29 | Release date: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex. Nat.Plants, 8, 2022
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6X2K
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7ZMH
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![BU of 7zmh by Molmil](/molmil-images/mine/7zmh) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Laube, E, Kuehlbrandt, W. | Deposit date: | 2022-04-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.47 Å) | Cite: | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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7ZM8
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![BU of 7zm8 by Molmil](/molmil-images/mine/7zm8) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Laube, E, Kuehlbrandt, W. | Deposit date: | 2022-04-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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6X0A
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![BU of 6x0a by Molmil](/molmil-images/mine/6x0a) | X-ray structure of a chimeric ParDE toxin-antitoxin complex from Mesorhizobium opportunistum | Descriptor: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Plasmid stabilization system, Putative addiction module antidote protein, ... | Authors: | Lite, T.L, Grant, R.A, Laub, M.T. | Deposit date: | 2020-05-15 | Release date: | 2020-11-25 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library. Elife, 9, 2020
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7ZM7
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![BU of 7zm7 by Molmil](/molmil-images/mine/7zm7) | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | Authors: | Laube, E, Kuehlbrandt, W. | Deposit date: | 2022-04-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-07 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum. Sci Adv, 8, 2022
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7U4T
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![BU of 7u4t by Molmil](/molmil-images/mine/7u4t) | Human V-ATPase in state 2 with SidK and mEAK-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ... | Authors: | Wang, L, Fu, T.M. | Deposit date: | 2022-03-01 | Release date: | 2022-08-24 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining. Proc.Natl.Acad.Sci.USA, 119, 2022
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6WDM
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![BU of 6wdm by Molmil](/molmil-images/mine/6wdm) | Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-B2) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Demo, G, Korostelev, A.A. | Deposit date: | 2020-03-31 | Release date: | 2020-07-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading. Nature, 584, 2020
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