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7LJ1
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BU of 7lj1 by Molmil
Human Prx1-Srx Decameric Complex
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T.
Deposit date:2021-01-28
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.
Antioxidants (Basel), 10, 2021
2WSP
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BU of 2wsp by Molmil
Thermotoga maritima alpha-L-fucosynthase, TmD224G, in complex with alpha-L-Fuc-(1-2)-beta-L-Fuc-N3
Descriptor: ALPHA-L-FUCOSIDASE, PUTATIVE, alpha-L-fucopyranose-(1-2)-beta-L-fucosyl-azide
Authors:Sulzenbacher, G, Lipski, A, Cobucci-Ponzano, B, Conte, F, Bedini, E, Corsaro, M.M, Parrilli, M, Dal Piaz, F, Lepore, L, Rossi, M, Moracci, M.
Deposit date:2009-09-08
Release date:2010-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Beta-Glycosyl Azides as Substrates for Alpha-Glycosynthases: Preparation of Novel Efficient Alpha-L-Fucosynthases
Chem.Biol., 16, 2009
3GE3
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BU of 3ge3 by Molmil
Crystal Structure of the reduced Toluene 4-Monooxygenase HD T201A mutant complex
Descriptor: ACETATE ION, CHLORIDE ION, FE (III) ION, ...
Authors:Elsen, N.L, Bailey, L.J, Fox, B.G.
Deposit date:2009-02-24
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase.
Biochemistry, 48, 2009
5CZZ
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BU of 5czz by Molmil
Crystal structure of Staphylococcus aureus Cas9 in complex with sgRNA and target DNA (TTGAAT PAM)
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, DNA (28-MER), ...
Authors:Nishimasu, H, Ishitani, R, Nureki, O.
Deposit date:2015-08-01
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Staphylococcus aureus Cas9.
Cell, 162, 2015
7RDB
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BU of 7rdb by Molmil
Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL)
Descriptor: Tetraspanin-15
Authors:Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C.
Deposit date:2021-07-09
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.
Structure, 30, 2022
5EOS
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BU of 5eos by Molmil
Crystallizing Strained DNA: Self-Assembly of 3D Crystals Containing a Torsionally-Stressed Component
Descriptor: DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*T)-3'), ...
Authors:Hernandez, C, Birktoft, J.J, Seeman, N.C.
Deposit date:2015-11-10
Release date:2017-08-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Self-Assembly of 3D DNA Crystals Containing a Torsionally Stressed Component.
Cell Chem Biol, 2017
3GEP
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BU of 3gep by Molmil
Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine
Descriptor: Hypoxanthine-guanine phosphoribosyltransferase, {[(1S)-2-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1-(hydroxymethyl)ethoxy]methyl}phosphonic acid
Authors:Guddat, L.W, Keough, D.T, Jersey, J.
Deposit date:2009-02-25
Release date:2009-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics.
J.Med.Chem., 52, 2009
2WU5
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BU of 2wu5 by Molmil
Crystal structure of the E. coli succinate:quinone oxidoreductase (SQR) SdhD His71Met mutant
Descriptor: 2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
Authors:Ruprecht, J, Yankovskaya, V, Maklashina, E, Iwata, S, Cecchini, G.
Deposit date:2009-09-29
Release date:2010-08-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Crystal Structure of the E. Coli Succinate:Quinone Oxidoreductase (Sqr) Sdhd His71met Mutant
To be Published
2CEU
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BU of 2ceu by Molmil
Despentapeptide insulin in acetic acid (pH 2)
Descriptor: INSULIN, SULFATE ION
Authors:Whittingham, J.L, Zhang, Y, Zakova, L, Dodson, E.J, Turkenburg, J.P, Brange, J, Dodson, G.G.
Deposit date:2006-02-10
Release date:2006-03-03
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:I222 Crystal Form of Despentapeptide (B26-B30) Insulin Provides New Insights Into the Properties of Monomeric Insulin.
Acta Crystallogr.,Sect.D, 62, 2006
2CII
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BU of 2cii by Molmil
The crystal structure of H-2Db complexed with a partial peptide epitope suggests an MHC Class I assembly-intermediate
Descriptor: BETA-2-MICROGLOBULIN, GLYCEROL, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, ...
Authors:Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E.Y, Elliott, T.
Deposit date:2006-03-21
Release date:2006-03-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.
J. Biol. Chem., 281, 2006
3C6N
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BU of 3c6n by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Descriptor: (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
Authors:Tan, X, Zheng, N, Hayashi, K.
Deposit date:2008-02-04
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3FRG
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BU of 3frg by Molmil
Catalytic Domain of Human Phosphodiesterase 4B2B in Complex with a Quinoline Inhibitor
Descriptor: 4-[(3-methoxyphenyl)amino]-6-(methylsulfonyl)quinoline-3-carboxamide, ARSENIC, GLYCEROL, ...
Authors:Somers, D.O, Neu, M.
Deposit date:2009-01-08
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.
Bioorg.Med.Chem.Lett., 19, 2009
4N4A
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BU of 4n4a by Molmil
Cystal structure of Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Authors:Smietanski, M, Werener, M, Purta, E, Kaminska, K.H, Stepinski, J, Darzynkiewicz, E, Nowotny, M, Bujnicki, J.M.
Deposit date:2013-10-08
Release date:2014-01-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Nat Commun, 5, 2014
8W9C
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BU of 8w9c by Molmil
Cryo-EM structure of the Rpd3S complex from budding yeast
Descriptor: Chromatin modification-related protein EAF3, Histone deacetylase RPD3, POTASSIUM ION, ...
Authors:Wang, C, Zhan, X.
Deposit date:2023-09-05
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures and dynamics of Rpd3S complex bound to nucleosome.
Sci Adv, 10, 2024
7RD5
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BU of 7rd5 by Molmil
Crystal structure of Tspan15 large extracellular loop (Tspan15 LEL) in complex with 1C12 Fab
Descriptor: 1C12 Fab Heavy Chain, 1C12 Fab Light Chain, Tetraspanin-15
Authors:Lipper, C.H, Gabriel, K.H, Seegar, T.C.M, Durr, K.L, Tomlinson, M.G, Blacklow, S.C.
Deposit date:2021-07-09
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site.
Structure, 30, 2022
2X6X
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BU of 2x6x by Molmil
Tailspike protein mutant D339N of E.coli bacteriophage HK620 in complex with hexasaccharide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TAILSPIKE PROTEIN HK620, alpha-L-rhamnopyranose-(1-6)-alpha-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)]alpha-D-galactopyranose
Authors:Lorenzen, N.K, Mueller, J.J, Heinemann, U, Seckler, R, Barbirz, S.
Deposit date:2010-02-22
Release date:2011-03-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Single Amino Acid Exchange in Bacteriophage Hk620 Tailspike Protein Results in Thousand-Fold Increase of its Oligosaccharide Affinity.
Glycobiology, 23, 2013
5EKA
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BU of 5eka by Molmil
HU DNA-binding protein from Thermus thermophilus
Descriptor: DNA-binding protein HU, GLYCEROL
Authors:Papageorgiou, A, Adam, P, Stavros, P, Nounesis, G, Meijers, R, Petratos, K, Vorgias, C.E.
Deposit date:2015-11-03
Release date:2016-07-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.
Extremophiles, 20, 2016
5D27
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BU of 5d27 by Molmil
Crystal Structure of the P-Rex1 PH domain
Descriptor: NICKEL (II) ION, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Authors:Cash, J.N, Tesmer, J.J.G.
Deposit date:2015-08-05
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
Structure, 24, 2016
4N5Y
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BU of 4n5y by Molmil
Crystal structure of H5 hemagglutinin mutant (N158D, N224K and Q226L) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-10-10
Release date:2013-11-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1615 Å)
Cite:Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
7JN7
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BU of 7jn7 by Molmil
Human DPP9-CARD8 complex
Descriptor: Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9, [(2~{R})-1-[(2~{R})-2-azanyl-3-methyl-butanoyl]pyrrolidin-2-yl]boronic acid
Authors:Sharif, H, Hollingsworth, L.R.
Deposit date:2020-08-04
Release date:2021-05-19
Last modified:2021-07-28
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Immunity, 54, 2021
1OHR
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BU of 1ohr by Molmil
VIRACEPT (R) (NELFINAVIR MESYLATE, AG1343): A POTENT ORALLY BIOAVAILABLE INHIBITOR OF HIV-1 PROTEASE
Descriptor: 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE, ASPARTYLPROTEASE
Authors:Davies II, J.F.
Deposit date:1997-09-27
Release date:1998-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease.
J.Med.Chem., 40, 1997
5D3X
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BU of 5d3x by Molmil
Crystal Structure of the P-Rex1 PH domain with Inositol-(1,3,4,5)-Tetrakisphosphate Bound
Descriptor: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Authors:Cash, J.N, Tesmer, J.J.G.
Deposit date:2015-08-06
Release date:2016-04-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
Structure, 24, 2016
7R86
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BU of 7r86 by Molmil
Structure of mouse BAI1 (ADGRB1) in complex with mouse Nogo receptor (RTN4R)
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AMINOBENZOIC ACID, ...
Authors:Miao, Y, Jude, K.M, Garcia, K.C.
Deposit date:2021-06-26
Release date:2021-11-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Cell, 184, 2021
5ELL
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BU of 5ell by Molmil
Crystal structure of L-aspartate/glutamate-specific racemase from Escherichia coli
Descriptor: Asp/Glu_racemase family protein
Authors:Ahn, J.W, Chang, J.H, Kim, K.J.
Deposit date:2015-11-04
Release date:2015-11-18
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural basis for an atypical active site of an l-aspartate/glutamate-specific racemase from Escherichia coli
Febs Lett., 589, 2015
5D2M
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BU of 5d2m by Molmil
Complex between human SUMO2-RANGAP1, UBC9 and ZNF451
Descriptor: 1,2-ETHANEDIOL, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ...
Authors:Cappadocia, L, Lima, C.D.
Deposit date:2015-08-05
Release date:2015-11-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase.
Nat.Struct.Mol.Biol., 22, 2015

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