5PBQ
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![BU of 5pbq by Molmil](/molmil-images/mine/5pbq) | PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 11) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-03 | Release date: | 2017-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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5PC5
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![BU of 5pc5 by Molmil](/molmil-images/mine/5pc5) | PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 26) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-03 | Release date: | 2017-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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5PCM
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![BU of 5pcm by Molmil](/molmil-images/mine/5pcm) | PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 43) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-03 | Release date: | 2017-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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5PD5
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![BU of 5pd5 by Molmil](/molmil-images/mine/5pd5) | PanDDA analysis group deposition -- Crystal Structure of BAZ2B after initial refinement with no ligand modelled (structure 61) | Descriptor: | 1,2-ETHANEDIOL, Bromodomain adjacent to zinc finger domain protein 2B | Authors: | Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Vollmar, M, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. | Deposit date: | 2017-02-03 | Release date: | 2017-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
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4J23
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![BU of 4j23 by Molmil](/molmil-images/mine/4j23) | Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex | Descriptor: | Fibroblast growth factor 1, Fibroblast growth factor receptor 2 | Authors: | Kudlinzki, D, Saxena, K, Sreeramulu, S, Schieborr, U, Dreyer, M, Schreuder, H, Schwalbe, H. | Deposit date: | 2013-02-04 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.882 Å) | Cite: | Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell, 23, 2013
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3BDM
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![BU of 3bdm by Molmil](/molmil-images/mine/3bdm) | yeast 20S proteasome:glidobactin A-complex | Descriptor: | (2E,4E)-N-[(2S,3R)-3-hydroxy-1-[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]-1-ox obutan-2-yl]dodeca-2,4-dienamide, Proteasome component C1, Proteasome component C11, ... | Authors: | Groll, M, Dudler, R, Kaiser, M. | Deposit date: | 2007-11-15 | Release date: | 2008-04-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism Nature, 452, 2008
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1BV9
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![BU of 1bv9 by Molmil](/molmil-images/mine/1bv9) | HIV-1 PROTEASE (I84V) COMPLEXED WITH XV638 OF DUPONT PHARMACEUTICALS | Descriptor: | PROTEIN (HIV-1 PROTEASE), [4R-(4ALPHA,5ALPHA,6BETA,7BETA)]-3,3'-[[TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-D IYL] BIS(METHYLENE)]BIS[N-2-THIAZOLYLBENZAMIDE] | Authors: | Ala, P, Chang, C.H. | Deposit date: | 1998-09-22 | Release date: | 1998-09-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities. Biochemistry, 37, 1998
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2MF0
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![BU of 2mf0 by Molmil](/molmil-images/mine/2mf0) | Structural basis of the non-coding RNA RsmZ acting as protein sponge: Conformer L of RsmZ(1-72)/RsmE(dimer) 1to3 complex | Descriptor: | Carbon storage regulator homolog, RNA_(72-MER) | Authors: | Duss, O, Michel, E, Yulikov, M, Schubert, M, Jeschke, G, Allain, F.H.-T. | Deposit date: | 2013-10-02 | Release date: | 2014-05-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of the non-coding RNA RsmZ acting as a protein sponge. Nature, 509, 2014
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1O71
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![BU of 1o71 by Molmil](/molmil-images/mine/1o71) | Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with glycerol | Descriptor: | GLYCEROL, STICHOLYSIN II | Authors: | Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A. | Deposit date: | 2002-10-23 | Release date: | 2003-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation Structure, 11, 2003
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1O72
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![BU of 1o72 by Molmil](/molmil-images/mine/1o72) | Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with phosphorylcholine | Descriptor: | PHOSPHOCHOLINE, STICHOLYSIN II | Authors: | Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A. | Deposit date: | 2002-10-23 | Release date: | 2003-11-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation Structure, 11, 2003
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3JXF
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![BU of 3jxf by Molmil](/molmil-images/mine/3jxf) | CA-like domain of human PTPRZ | Descriptor: | Receptor-type tyrosine-protein phosphatase zeta | Authors: | Bouyain, S. | Deposit date: | 2009-09-19 | Release date: | 2009-12-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Proc.Natl.Acad.Sci.USA, 107, 2010
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2MF1
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![BU of 2mf1 by Molmil](/molmil-images/mine/2mf1) | Structural basis of the non-coding RNA RsmZ acting as protein sponge: Conformer R of RsmZ(1-72)/RsmE(dimer) 1to3 complex | Descriptor: | Carbon storage regulator homolog, RNA_(72-MER) | Authors: | Duss, O, Michel, E, Yulikov, M, Schubert, M, Jeschke, G, Allain, F.H.-T. | Deposit date: | 2013-10-02 | Release date: | 2014-05-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of the non-coding RNA RsmZ acting as a protein sponge. Nature, 509, 2014
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3JXH
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![BU of 3jxh by Molmil](/molmil-images/mine/3jxh) | CA-like domain of human PTPRG | Descriptor: | Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION | Authors: | Bouyain, S. | Deposit date: | 2009-09-19 | Release date: | 2009-12-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. Proc.Natl.Acad.Sci.USA, 107, 2010
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3WSU
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![BU of 3wsu by Molmil](/molmil-images/mine/3wsu) | Crystal structure of beta-mannanase from Streptomyces thermolilacinus | Descriptor: | Beta-mannanase, GLYCEROL, SODIUM ION | Authors: | Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A. | Deposit date: | 2014-03-26 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition Febs J., 282, 2015
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6ZSS
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![BU of 6zss by Molmil](/molmil-images/mine/6zss) | |
6ZZE
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![BU of 6zze by Molmil](/molmil-images/mine/6zze) | |
2MPK
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![BU of 2mpk by Molmil](/molmil-images/mine/2mpk) | |
6FP4
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![BU of 6fp4 by Molmil](/molmil-images/mine/6fp4) | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,8-Naphthyridine-2-carboxylic acid | Descriptor: | (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 1,8-naphthyridine-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | Deposit date: | 2018-02-09 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6ZZF
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6FMZ
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![BU of 6fmz by Molmil](/molmil-images/mine/6fmz) | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,4-Bis(2-hydroxyethyl)piperazine | Descriptor: | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | Authors: | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | Deposit date: | 2018-02-02 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6ZSO
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![BU of 6zso by Molmil](/molmil-images/mine/6zso) | Solution structure of the water-soluble LU-domain of human Lypd6b protein | Descriptor: | Ly6/PLAUR domain-containing protein 6B | Authors: | Tsarev, A.V, Kulbatskii, D.S, Paramonov, A.S, Lyukmanova, E.N, Shenkarev, Z.O. | Deposit date: | 2020-07-16 | Release date: | 2021-01-13 | Method: | SOLUTION NMR | Cite: | Structural Diversity and Dynamics of Human Three-Finger Proteins Acting on Nicotinic Acetylcholine Receptors. Int J Mol Sci, 21, 2020
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6FTC
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![BU of 6ftc by Molmil](/molmil-images/mine/6ftc) | Thioredoxin glutathione reductase from Schistosoma mansoni in complex with HEPES | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | Deposit date: | 2018-02-21 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6FMU
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![BU of 6fmu by Molmil](/molmil-images/mine/6fmu) | Thioredoxin glutathione reductase from Schistosome mansoni in complex with 2-[4-(4-amino-butyl)-piperazin-1-yl]-ethanol | Descriptor: | 2-[4-(4-azanylbutyl)piperazin-1-yl]ethanol, FLAVIN-ADENINE DINUCLEOTIDE, TRIETHYLENE GLYCOL, ... | Authors: | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | Deposit date: | 2018-02-02 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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2G5O
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![BU of 2g5o by Molmil](/molmil-images/mine/2g5o) | Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide | Descriptor: | (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | Deposit date: | 2006-02-23 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide To be Published
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4B8X
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![BU of 4b8x by Molmil](/molmil-images/mine/4b8x) | Near atomic resolution crystal structure of Sco5413, a MarR family transcriptional regulator from Streptomyces coelicolor | Descriptor: | CHLORIDE ION, POSSIBLE MARR-TRANSCRIPTIONAL REGULATOR | Authors: | Holley, T.A, Stevenson, C.E.M, Bibb, M.J, Lawson, D.M. | Deposit date: | 2012-08-31 | Release date: | 2012-10-17 | Last modified: | 2019-05-22 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | High Resolution Crystal Structure of Sco5413, a Widespread Actinomycete Marr Family Transcriptional Regulator of Unknown Function. Proteins, 81, 2013
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