6OAI
 
 | | Crystal structure of P[6] rotavirus vp8* complexed with LNFPI | | Descriptor: | Protease-sensitive outer capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Xu, S, Liu, Y, Jiang, X, Kennedy, M.A. | | Deposit date: | 2019-03-16 | | Release date: | 2020-03-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.
Plos Pathog., 16, 2020
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6OAN
 | | Structure of DBP in complex with human neutralizing antibody 053054 | | Descriptor: | Antibody 053054 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | | Authors: | Urusova, D, Tolia, N.H. | | Deposit date: | 2019-03-18 | | Release date: | 2019-06-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
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2VUX
 | | Human ribonucleotide reductase, subunit M2 B | | Descriptor: | FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B | | Authors: | Welin, M, Moche, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Svensson, L, Thorsell, A.G, Tresaugues, L, van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-05-31 | | Release date: | 2008-07-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Human Ribonucleotide Reductase, Subunit M2 B
To be Published
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6OAO
 | | Structure of DBP in complex with human neutralizing antibody 092096 | | Descriptor: | Antibody 092096 single chain variable fragment, Duffy binding surface protein region II, SULFATE ION | | Authors: | Urusova, D, Tolia, N.H. | | Deposit date: | 2019-03-18 | | Release date: | 2019-06-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.497 Å) | | Cite: | Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.
Nat Microbiol, 4, 2019
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2W49
 | | ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, CALCIUM ION, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-11-24 | | Release date: | 2010-05-05 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
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6OES
 | | Cryo-EM structure of mouse RAG1/2 STC complex (without NBD domain) | | Descriptor: | CALCIUM ION, DNA (34-MER), DNA (35-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
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6OEP
 | | Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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2W4U
 | | Isometrically contracting insect asynchronous flight muscle quick frozen after a length step | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-12-02 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
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6BHX
 | | B. subtilis SsbA with DNA | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein A | | Authors: | Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L. | | Deposit date: | 2017-10-31 | | Release date: | 2018-12-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.936 Å) | | Cite: | Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.
J. Mol. Biol., 431, 2019
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6BLQ
 | | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, Y, Dai, S. | | Deposit date: | 2017-11-11 | | Release date: | 2017-12-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1XLM
 | | D254E, D256E MUTANT OF D-XYLOSE ISOMERASE COMPLEXED WITH AL3 AND XYLITOL | | Descriptor: | ALUMINUM ION, D-XYLOSE ISOMERASE, Xylitol | | Authors: | Gerczei, T, Bocskei, Z.S, Szabo, E, Naray-Szabo, G, Asboth, B. | | Deposit date: | 1997-07-22 | | Release date: | 1998-01-28 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure determination and refinement of the Al3+ complex of the D254,256E mutant of Arthrobacter D-xylose isomerase at 2.40 A resolution. Further evidence for inhibitor-induced metal ion movement.
Int.J.Biol.Macromol., 25, 1999
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7RC0
 | | X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-091-20 | | Descriptor: | 3C-like proteinase, 5-chloro-4-methylpyridin-3-yl 1H-indole-4-carboxylate, SODIUM ION | | Authors: | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-06 | | Release date: | 2021-09-29 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.
J.Med.Chem., 64, 2021
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7RC1
 | | X-ray Structure of SARS-CoV main protease covalently modified by compound GRL-0686 | | Descriptor: | 3C-like proteinase, 5-chloropyridin-3-yl 1-(3-nitrobenzene-1-sulfonyl)-1H-indole-5-carboxylate, DIMETHYL SULFOXIDE | | Authors: | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-07 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.
J.Med.Chem., 64, 2021
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7RBZ
 | | X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-017-20 | | Descriptor: | 3C-like proteinase, 5-chloropyridin-3-yl 2,3-dihydro-1H-indole-4-carboxylate | | Authors: | Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-06 | | Release date: | 2021-09-29 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies.
J.Med.Chem., 64, 2021
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6PIL
 | | Antibody scFv-M204 monomeric state | | Descriptor: | CHLORIDE ION, scFv-M204 antibody | | Authors: | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | | Deposit date: | 2019-06-26 | | Release date: | 2020-06-24 | | Last modified: | 2020-08-12 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J.Biol.Chem., 295, 2020
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6OEN
 | | Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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4WXS
 | | Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain | | Descriptor: | CALCIUM ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | Authors: | Donegan, R.K, Freeman, D.M, Lieberman, R.L. | | Deposit date: | 2014-11-14 | | Release date: | 2015-04-01 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for misfolding in myocilin-associated glaucoma.
Hum.Mol.Genet., 24, 2015
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6OER
 | | Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2) | | Descriptor: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
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2VYP
 | | Rabbit-muscle G-actin in complex with myxobacterial rhizopodin | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Hagelueken, G, Albrecht, S.C, Steinmetz, H, Jansen, R, Heinz, D.W, Kalesse, M, Schubert, W.-D. | | Deposit date: | 2008-07-25 | | Release date: | 2009-02-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The Absolute Configuration of Rhizopodin and its Inhibition of Actin Polymerization by Dimerization.
Angew.Chem.Int.Ed.Engl., 48, 2009
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6BLX
 | | Crystal structure of IAg7 in complex with insulin mimotope p8G9E | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wang, Y, Dai, S. | | Deposit date: | 2017-11-11 | | Release date: | 2017-12-20 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.323 Å) | | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BZ1
 | | MEF2 Chimera D83V mutant/DNA complex | | Descriptor: | DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), MEF2 CHIMERA | | Authors: | Lei, X, Chen, L. | | Deposit date: | 2017-12-21 | | Release date: | 2018-02-07 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | The Cancer Mutation D83V Induces an alpha-Helix to beta-Strand Conformation Switch in MEF2B.
J. Mol. Biol., 430, 2018
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6BLR
 | | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS | | Descriptor: | 1,2-ETHANEDIOL, H2-Ab1 protein, IAg7 alpha chain | | Authors: | Wang, Y, Dai, S. | | Deposit date: | 2017-11-11 | | Release date: | 2017-12-20 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6OET
 | | Cryo-EM structure of mouse RAG1/2 STC complex | | Descriptor: | CALCIUM ION, DNA (30-MER), DNA (39-MER), ... | | Authors: | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | | Deposit date: | 2019-03-27 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
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5TH6
 | | Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9) | | Descriptor: | CALCIUM ION, Matrix metalloproteinase-9,Matrix metalloproteinase-9, ZINC ION | | Authors: | Appleby, T.C, Greenstein, A.E, Kwon, H.J. | | Deposit date: | 2016-09-29 | | Release date: | 2017-03-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
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5TH9
 | | Structure determination of a potent, selective antibody inhibitor of human MMP9 (GS-5745 bound to MMP-9) | | Descriptor: | CALCIUM ION, COBALT HEXAMMINE(III), GS-5745 Fab heavy chain, ... | | Authors: | Appleby, T.C, Greenstein, A.E, Kwon, H.J. | | Deposit date: | 2016-09-29 | | Release date: | 2017-03-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.999 Å) | | Cite: | Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J. Biol. Chem., 292, 2017
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