5TH6
Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9)
Summary for 5TH6
Entry DOI | 10.2210/pdb5th6/pdb |
Related | 5TH9 |
Descriptor | Matrix metalloproteinase-9,Matrix metalloproteinase-9, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | metalloproteinase-9 antibody inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted, extracellular space, extracellular matrix : P14780 |
Total number of polymer chains | 4 |
Total formula weight | 104852.65 |
Authors | Appleby, T.C.,Greenstein, A.E.,Kwon, H.J. (deposition date: 2016-09-29, release date: 2017-03-01, Last modification date: 2023-10-04) |
Primary citation | Appleby, T.C.,Greenstein, A.E.,Hung, M.,Liclican, A.,Velasquez, M.,Villasenor, A.G.,Wang, R.,Wong, M.H.,Liu, X.,Papalia, G.A.,Schultz, B.E.,Sakowicz, R.,Smith, V.,Kwon, H.J. Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9. J. Biol. Chem., 292:6810-6820, 2017 Cited by PubMed: 28235803DOI: 10.1074/jbc.M116.760579 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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