5TH6
Structure determination of a potent, selective antibody inhibitor of human MMP9 (apo MMP9)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Matrix metalloproteinase-9,Matrix metalloproteinase-9 | polymer | 231 | 25962.1 | 4 | UniProt (P14780) Pfam (PF00413) In PDB | Homo sapiens (Human) | MMP-9,92 kDa gelatinase,92 kDa type IV collagenase,Gelatinase B,GELB,MMP-9,92 kDa gelatinase,92 kDa type IV collagenase,Gelatinase B,GELB |
| 2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 12 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 921 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 40 - 215 (UniProt: P14780)
A, B, C, D: 391 - 443 (UniProt: P14780)
| PDB | External Database | Details |
|---|---|---|
| Met 38 | - | initiating methionine |
| Ala 39 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 103848.4 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1004.2 | |
| All* | Total formula weight | 104852.7 |
