5DZO
 
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5ELI
 | | Triggering receptor expressed on myeloid cells 2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Triggering receptor expressed on myeloid cells 2 | | Authors: | Brett, T.J, Kober, D.L. | | Deposit date: | 2015-11-04 | | Release date: | 2016-12-28 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.0977 Å) | | Cite: | Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.
Elife, 5, 2016
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5F7F
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5F1S
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5F71
 | | Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3) | | Descriptor: | Hepatitis A virus cellular receptor 2, SODIUM ION | | Authors: | Gao, G.F, Lu, G, Wang, H, Qi, J. | | Deposit date: | 2015-12-07 | | Release date: | 2016-02-03 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.404 Å) | | Cite: | Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Chin.Sci.Bull., 60, 2015
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5F70
 | | Crystal structures of human TIM members | | Descriptor: | Hepatitis A virus cellular receptor 1 | | Authors: | Gao, G.F, Lu, G, Wang, H, Qi, J. | | Deposit date: | 2015-12-07 | | Release date: | 2016-02-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Chin.Sci.Bull., 60, 2015
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5F7H
 | | Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine | | Descriptor: | CALCIUM ION, PHOSPHOSERINE, T-cell immunoglobulin and mucin domain-containing protein 4 | | Authors: | Gao, G.F, Lu, G, Wang, H, Qi, J. | | Deposit date: | 2015-12-08 | | Release date: | 2016-02-03 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Chin.Sci.Bull., 60, 2015
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5EDX
 | | Crystal structure of swine CD8aa homodimer | | Descriptor: | CD8 alpha antigen | | Authors: | Liu, Y.J, Qi, J.X, Zhang, N.Z, Xia, C. | | Deposit date: | 2015-10-22 | | Release date: | 2016-09-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
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5EBG
 | | Crystal structure of bovine CD8aa homodimer | | Descriptor: | T-cell surface glycoprotein CD8 alpha chain | | Authors: | Liu, Y, Li, X, Zhang, N, Qi, J, Xia, C. | | Deposit date: | 2015-10-19 | | Release date: | 2016-09-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
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5FFL
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5FDY
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5DZN
 | | human T-cell immunoglobulin and mucin domain protein 4 | | Descriptor: | T-cell immunoglobulin and mucin domain-containing protein 4 | | Authors: | Yuan, S, Rao, Z, Wang, X. | | Deposit date: | 2015-09-25 | | Release date: | 2015-11-25 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | TIM-1 acts a dual-attachment receptor for Ebolavirus by interacting directly with viral GP and the PS on the viral envelope.
Protein Cell, 6, 2015
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5FEB
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5GGS
 | | PD-1 in complex with pembrolizumab Fab | | Descriptor: | Programmed cell death protein 1, heavy chain, light chain | | Authors: | Heo, Y.S. | | Deposit date: | 2016-06-16 | | Release date: | 2016-11-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
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5GGV
 | | CTLA-4 in complex with tremelimumab Fab | | Descriptor: | Cytotoxic T-lymphocyte protein 4, heavy chain, light chain | | Authors: | Heo, Y.S. | | Deposit date: | 2016-06-16 | | Release date: | 2016-11-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Nat Commun, 7, 2016
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2JJU
 | | Structure of human signal regulatory protein (sirp) beta | | Descriptor: | CHLORIDE ION, SIGNAL REGULATORY PROTEIN BETA-1, SULFATE ION | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2JJW
 | | Structure of human signal regulatory protein (sirp) gamma | | Descriptor: | SIGNAL REGULATORY PROTEIN GAMMA | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2J1K
 | | CAV-2 fibre head in complex with CAR D1 | | Descriptor: | COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | | Deposit date: | 2006-08-14 | | Release date: | 2006-09-05 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
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2ICC
 | | Extracellular Domain of CRIg | | Descriptor: | V-set and immunoglobulin domain-containing protein 4 | | Authors: | Wiesmann, C. | | Deposit date: | 2006-09-12 | | Release date: | 2006-11-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
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2JJV
 | | Structure of human signal regulatory protein (sirp) beta(2) | | Descriptor: | CHLORIDE ION, SIGNAL-REGULATORY PROTEIN BETA 1., SULFATE ION | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2MMX
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2MCP
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2MKW
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2M2D
 | | Human programmed cell death 1 receptor | | Descriptor: | Programmed cell death protein 1 | | Authors: | Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D. | | Deposit date: | 2012-12-18 | | Release date: | 2013-02-27 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Structure and interactions of the human programmed cell death 1 receptor.
J.Biol.Chem., 288, 2013
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2MCG
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