5ELI

Triggering receptor expressed on myeloid cells 2

Summary for 5ELI

• Entry DOI: 10.2210/pdb5eli/pdb
• Descriptor: Triggering receptor expressed on myeloid cells 2, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: activating receptors, trem2, innate immunity, immune system receptor, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 28740.40

Authors

Brett, T.J.,Kober, D.L. (deposition date: 2015-11-04, release date: 2016-12-28, Last modification date: 2023-09-27)

• Primary citation: Kober, D.L.,Alexander-Brett, J.M.,Karch, C.M.,Cruchaga, C.,Colonna, M.,Holtzman, M.J.,Brett, T.J.; Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.; Elife, 5:-, 2016; PubMed: 27995897; DOI: 10.7554/eLife.20391

Experimental method

X-RAY DIFFRACTION (3.0977 Å)