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6UV2
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BU of 6uv2 by Molmil
Crystal structure of the core domain of RNA helicase DDX17 with RNA pri-125a-oligo1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Ngo, T.D, Partin, A.C, Nam, Y.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Cell Rep, 29, 2019
5SVZ
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BU of 5svz by Molmil
HIV-1 Tat NLS in complex with importin alpha
Descriptor: Importin subunit alpha-1, Tat
Authors:Smith, K.M, Himiari, Z, Forwood, J.K.
Deposit date:2016-08-08
Release date:2016-08-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Importin-alpha Binding of the Human Immunodeficiency Virus Tat.
Sci Rep, 7, 2017
5V61
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BU of 5v61 by Molmil
Phospho-ERK2 bound to bivalent inhibitor SBP2
Descriptor: 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid, 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, ...
Authors:Lechtenberg, B.C, Riedl, S.J.
Deposit date:2017-03-15
Release date:2017-07-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
ACS Med Chem Lett, 8, 2017
1K5K
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BU of 1k5k by Molmil
Homonuclear 1H Nuclear Magnetic Resonance Assignment and Structural Characterization of HIV-1 Tat Mal Protein
Descriptor: TAT protein
Authors:Gregoire, C, Peloponese, J.M, Esquieu, D, Opi, S, Campbell, G, Solomiac, M, Lebrun, E, Lebreton, J, Loret, E.P.
Deposit date:2001-10-11
Release date:2002-06-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein.
Biopolymers, 62, 2001
7U50
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BU of 7u50 by Molmil
APE1 bound to a nucleosome core particle with AP-site at SHL-6
Descriptor: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
Authors:Weaver, T.M, Freudenthal, B.D.
Deposit date:2022-03-01
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
1NFI
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BU of 1nfi by Molmil
I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX
Descriptor: I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65
Authors:Jacobs, M.D, Harrison, S.C.
Deposit date:1998-08-25
Release date:1998-11-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of an IkappaBalpha/NF-kappaB complex.
Cell(Cambridge,Mass.), 95, 1998
2NLL
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BU of 2nll by Molmil
RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Descriptor: DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*GP*AP*AP*AP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (RETINOIC ACID RECEPTOR), ...
Authors:Rastinejad, F, Perlmann, T, Evans, R.M, Sigler, P.B.
Deposit date:1996-11-20
Release date:1997-03-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of nuclear receptor assembly on DNA direct repeats.
Nature, 375, 1995
2QC8
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BU of 2qc8 by Molmil
Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Glutamine synthetase, ...
Authors:Karlberg, T, Lehtio, L, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hogbom, M, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-06-19
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
4IEM
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BU of 4iem by Molmil
Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+
Descriptor: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*C)-3'), DNA (5'-D(P*(3DR)P*GP*AP*TP*CP*G)-3'), ...
Authors:Tsutakawa, S.E, Mol, C.D, Arvai, A.S, Tainer, J.A.
Deposit date:2012-12-13
Release date:2013-01-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3936 Å)
Cite:Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes.
J.Biol.Chem., 288, 2013
2OJW
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BU of 2ojw by Molmil
Crystal structure of human glutamine synthetase in complex with ADP and phosphate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
Authors:Karlberg, T, Uppenberg, J, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Hogbom, M, Johansson, I, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC)
Deposit date:2007-01-15
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J.Mol.Biol., 375, 2008
4IMY
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BU of 4imy by Molmil
The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
Descriptor: ADENOSINE MONOPHOSPHATE, AF4/FMR2 family member 4, Cyclin-T1, ...
Authors:Alber, T, Schulze-Gahmen, U.
Deposit date:2013-01-03
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.
Elife, 2, 2013
2RAM
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BU of 2ram by Molmil
A NOVEL DNA RECOGNITION MODE BY NF-KB P65 HOMODIMER
Descriptor: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, DNA (5'-D(*CP*GP*GP*CP*TP*GP*GP*AP*AP*AP*TP*(5IU)P*(5IU)P*CP*CP*AP*GP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR NF-KB P65)
Authors:Chen, Y.Q, Ghosh, S, Ghosh, G.
Deposit date:1997-11-23
Release date:1998-05-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel DNA recognition mode by the NF-kappa B p65 homodimer.
Nat.Struct.Biol., 5, 1998

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