5WE6
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![BU of 5we6 by Molmil](/molmil-images/mine/5we6) | 70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Fislage, M, Frank, J. | Deposit date: | 2017-07-07 | Release date: | 2018-04-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
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5O2R
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![BU of 5o2r by Molmil](/molmil-images/mine/5o2r) | Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N. | Deposit date: | 2017-05-22 | Release date: | 2017-07-26 | Last modified: | 2019-02-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. Nat. Struct. Mol. Biol., 24, 2017
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8K4E
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![BU of 8k4e by Molmil](/molmil-images/mine/8k4e) | |
8A3L
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![BU of 8a3l by Molmil](/molmil-images/mine/8a3l) | Structural insights into the binding of bS1 to the ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... | Authors: | D'Urso, G, Chat, S, Gillet, R, Giudice, E. | Deposit date: | 2022-06-08 | Release date: | 2023-05-10 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Structural insights into the binding of bS1 to the ribosome. Nucleic Acids Res., 51, 2023
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7ACR
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![BU of 7acr by Molmil](/molmil-images/mine/7acr) | Structure of post-translocated trans-translation complex on E. coli stalled ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | Deposit date: | 2020-09-11 | Release date: | 2021-08-18 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7AFD
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![BU of 7afd by Molmil](/molmil-images/mine/7afd) | Bacterial 30S ribosomal subunit assembly complex state A (head domain) | Descriptor: | 16SrRNA of the head domain (residue C931 to G1386), 30S ribosomal protein S10, 30S ribosomal protein S13, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | Deposit date: | 2020-09-19 | Release date: | 2021-07-07 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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4V4H
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![BU of 4v4h by Molmil](/molmil-images/mine/4v4h) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution. | Descriptor: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ... | Authors: | Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D. | Deposit date: | 2006-08-04 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structural analysis of kasugamycin inhibition of translation. Nat.Struct.Mol.Biol., 13, 2006
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4V4Q
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![BU of 4v4q by Molmil](/molmil-images/mine/4v4q) | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. | Deposit date: | 2005-08-30 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
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8RCL
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![BU of 8rcl by Molmil](/molmil-images/mine/8rcl) | |
4V64
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![BU of 4v64 by Molmil](/molmil-images/mine/4v64) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Shoji, S, Fredrick, K, Cate, J.H.D. | Deposit date: | 2008-06-11 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for hygromycin B inhibition of protein biosynthesis Rna, 14, 2008
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6X7F
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![BU of 6x7f by Molmil](/molmil-images/mine/6x7f) | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-05-29 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6WNV
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![BU of 6wnv by Molmil](/molmil-images/mine/6wnv) | 70S ribosome without free 5S rRNA and with a perturbed PTC | Descriptor: | 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | Deposit date: | 2020-04-23 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nat Commun, 11, 2020
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4V57
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![BU of 4v57 by Molmil](/molmil-images/mine/4v57) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin. | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. | Deposit date: | 2007-07-21 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
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7K51
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![BU of 7k51 by Molmil](/molmil-images/mine/7k51) | Mid-translocated non-frameshifting(CCA-A) complex with EF-G and GDPCP (Structure II) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Demo, G, Loveland, A.B, Svidritskiy, E, Gamper, H.B, Hou, Y.M, Korostelev, A.A. | Deposit date: | 2020-09-16 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation. Nat Commun, 12, 2021
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7JT2
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![BU of 7jt2 by Molmil](/molmil-images/mine/7jt2) | |
6BU8
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![BU of 6bu8 by Molmil](/molmil-images/mine/6bu8) | 70S ribosome with S1 domains 1 and 2 (Class 1) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... | Authors: | Loveland, A.B, Korostelev, A.A. | Deposit date: | 2017-12-08 | Release date: | 2018-01-31 | Last modified: | 2020-01-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM. Methods, 137, 2018
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6ZTL
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![BU of 6ztl by Molmil](/molmil-images/mine/6ztl) | E. coli 70S-RNAP expressome complex in collided state bound to NusG | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Webster, M.W, Takacs, M, Weixlbaumer, A. | Deposit date: | 2020-07-20 | Release date: | 2020-09-16 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of transcription-translation coupling and collision in bacteria. Science, 369, 2020
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7OJ0
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![BU of 7oj0 by Molmil](/molmil-images/mine/7oj0) | Cryo-EM structure of 70S ribosome stalled with TnaC peptide and RF2 | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Su, T, Kudva, R, Becker, T, Berninghausen, O, Heijne, G, Cheng, J, Beckmann, R. | Deposit date: | 2021-05-13 | Release date: | 2021-09-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide. Nucleic Acids Res., 49, 2021
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6ORL
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![BU of 6orl by Molmil](/molmil-images/mine/6orl) | RF1 pre-accommodated 70S complex at 24 ms | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-04-30 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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5U4I
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![BU of 5u4i by Molmil](/molmil-images/mine/5u4i) | Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Zeng, F, Chen, Y, Remis, J, Shekhar, M, Phillips, J.C, Tajkhorshid, E, Jin, H. | Deposit date: | 2016-12-04 | Release date: | 2017-01-11 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome. Nature, 541, 2017
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6OSQ
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![BU of 6osq by Molmil](/molmil-images/mine/6osq) | RF1 accommodated state bound Release complex 70S at long incubation time point | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-26 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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5LZE
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![BU of 5lze by Molmil](/molmil-images/mine/5lze) | Structure of the 70S ribosome with Sec-tRNASec in the classical pre-translocation state (C) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | Deposit date: | 2016-09-29 | Release date: | 2016-11-23 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The pathway to GTPase activation of elongation factor SelB on the ribosome. Nature, 540, 2016
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4V53
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![BU of 4v53 by Molmil](/molmil-images/mine/4v53) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | Descriptor: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | Authors: | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | Deposit date: | 2007-06-16 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.54 Å) | Cite: | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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7NAT
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![BU of 7nat by Molmil](/molmil-images/mine/7nat) | Bacterial 30S ribosomal subunit assembly complex state A (Consensus refinement) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | Deposit date: | 2021-01-25 | Release date: | 2021-12-08 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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7AFH
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![BU of 7afh by Molmil](/molmil-images/mine/7afh) | Bacterial 30S ribosomal subunit assembly complex state C (head domain) | Descriptor: | 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ... | Authors: | Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. | Deposit date: | 2020-09-19 | Release date: | 2021-07-07 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
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