1SE2
 
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1TY2
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | Descriptor: | ZINC ION, putative exotoxin (superantigen) | | Authors: | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | Deposit date: | 2004-07-07 | | Release date: | 2004-08-17 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
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1TY0
 | | Crystal structure of the streptococcal pyrogenic exotoxin J (SPE-J) | | Descriptor: | putative exotoxin (superantigen) | | Authors: | Baker, H.M, Proft, T, Webb, P.D, Arcus, V.L, Fraser, J.D, Baker, E.N. | | Deposit date: | 2004-07-06 | | Release date: | 2004-08-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystallographic and mutational data show that the streptococcal pyrogenic exotoxin j can use a common binding surface for T-cell receptor binding and dimerization
J.Biol.Chem., 279, 2004
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1SE4
 | | STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH LACTOSE | | Descriptor: | STAPHYLOCOCCAL ENTEROTOXIN B, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Swaminathan, S, Sax, M. | | Deposit date: | 1997-04-16 | | Release date: | 1997-10-15 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2, 1995
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1SE3
 | | STAPHYLOCOCCAL ENTEROTOXIN B COMPLEXED WITH GM3 TRISACCHARIDE | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, STAPHYLOCOCCAL ENTEROTOXIN B | | Authors: | Swaminathan, S, Sax, M. | | Deposit date: | 1996-10-11 | | Release date: | 1997-06-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Residues defining V beta specificity in staphylococcal enterotoxins.
Nat.Struct.Biol., 2, 1995
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1SBB
 | | T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SUPERANTIGEN SEB | | Descriptor: | PROTEIN (14.3.D T CELL ANTIGEN RECEPTOR), PROTEIN (STAPHYLOCOCCAL ENTEROTOXIN B) | | Authors: | Li, H, Mariuzza, R.A. | | Deposit date: | 1999-02-22 | | Release date: | 1999-03-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Three-dimensional structure of the complex between a T cell receptor beta chain and the superantigen staphylococcal enterotoxin B.
Immunity, 9, 1998
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1SEB
 | | COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB | | Descriptor: | ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ... | | Authors: | Jardetzky, T.S, Brown, J.H, Gorga, J.C, Stern, L.J, Urban, R.G, Chi, Y.I, Stauffacher, C, Strominger, J.L, Wiley, D.C. | | Deposit date: | 1995-11-26 | | Release date: | 1996-06-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Nature, 368, 1994
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1SXT
 | | STAPHYLOCOCCAL ENTEROTOXIN TYPE A (SEA) CO-CRYSTALLISED WITH ZINC | | Descriptor: | STAPHYLOCOCCAL ENTEROTOXIN TYPE A, ZINC ION | | Authors: | Sundstrom, S.M. | | Deposit date: | 1996-11-14 | | Release date: | 1997-11-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding.
J.Biol.Chem., 271, 1996
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1UUP
 | | Crystal Structure of A Dimeric Form of Streptococcal Pyrogenic Exotoxin A (SpeA1). | | Descriptor: | EXOTOXIN TYPE A, ZINC ION | | Authors: | Baker, M.D, Gendlina, I, Collins, C.M, Acharya, K.R. | | Deposit date: | 2004-01-08 | | Release date: | 2004-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of a Dimeric Form of Streptococcal Pyrogenic Exotoxin a (Spea1)
Protein Sci., 13, 2004
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1T5X
 | | HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2 | | Descriptor: | 15-mer peptide fragment of Regulatory protein MIG1, Enterotoxin type C-3, HLA class II histocompatibility antigen, ... | | Authors: | Zavala-Ruiz, Z, Strug, I, Anderson, M.W, Gorski, J, Stern, L.J. | | Deposit date: | 2004-05-05 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A Polymorphic Pocket at the P10 Position Contributes to Peptide Binding Specificity in Class II MHC Proteins
Chem.Biol., 11, 2004
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1SJE
 | | HLA-DR1 complexed with a 16 residue HIV capsid peptide bound in a hairpin conformation | | Descriptor: | Enterotoxin type C-3, GAG polyprotein, HLA class II histocompatibility antigen, ... | | Authors: | Zavala-Ruiz, Z, Strug, I, Walker, B.D, Norris, P.J, Stern, L.J. | | Deposit date: | 2004-03-03 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1UNS
 | | IDENTIFICATION OF A SECONDARY ZINC-BINDING SITE IN STAPHYLOCOCCAL ENTEROTOXIN C2: IMPLICATIONS FOR SUPERANTIGEN RECOGNITION | | Descriptor: | ENTEROTOXIN TYPE C-2, ZINC ION | | Authors: | Papageorgiou, A.C, Baker, M.D, McLeod, J.D, Goda, S, Sansom, D.M, Tranter, H.S, Acharya, K.R. | | Deposit date: | 2003-09-15 | | Release date: | 2003-11-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of a Secondary Zinc-Binding Site in Staphylococcal Enterotoxin C2: Implications for Superantigen Recognition
J.Biol.Chem., 279, 2004
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1SJH
 | | HLA-DR1 complexed with a 13 residue HIV capsid peptide | | Descriptor: | Enterotoxin type C-3, GAG polyprotein, HLA class II histocompatibility antigen, ... | | Authors: | Zavala-Ruiz, Z, Strug, I, Walker, B.D, Norris, P.J, Stern, L.J. | | Deposit date: | 2004-03-03 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1STE
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1I4P
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1KTK
 | | Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1) | | Descriptor: | Exotoxin type C, T-cell receptor beta chain | | Authors: | Sundberg, E.J, Li, H, Llera, A.S, McCormick, J.K, Tormo, J, Karjalainen, K, Schlievert, P.M, Mariuzza, R.A. | | Deposit date: | 2002-01-16 | | Release date: | 2002-06-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
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1KLG
 | | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | Deposit date: | 2001-12-11 | | Release date: | 2002-08-02 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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1I4R
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1I4Q
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1I4H
 | | Crystal structure of Zn2+ soaked Staphylococcal enterotoxin A mutant H187A | | Descriptor: | ENTEROTOXIN TYPE A, ZINC ION | | Authors: | Hakansson, M, Antonsson, P, Bjork, P, Svensson, L.A. | | Deposit date: | 2001-02-21 | | Release date: | 2001-02-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction
J.Biol.Inorg.Chem., 6, 2001
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1I4G
 | | Crystal structure of Staphylococcal enterotoxin A mutant H187A with reduced Zn2+ affinity | | Descriptor: | ENTEROTOXIN TYPE A, SULFATE ION, ZINC ION | | Authors: | Hakansson, M, Antonsson, P, Bjork, P, Svensson, L.A. | | Deposit date: | 2001-02-21 | | Release date: | 2001-02-28 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction
J.Biol.Inorg.Chem., 6, 2001
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1L0Y
 | | T cell receptor beta chain complexed with superantigen SpeA soaked with zinc | | Descriptor: | 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL, ... | | Authors: | Li, H, Sundberg, E.J, Mariuzza, R.A. | | Deposit date: | 2002-02-14 | | Release date: | 2002-04-03 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
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1KLU
 | | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | Descriptor: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | Authors: | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | Deposit date: | 2001-12-12 | | Release date: | 2002-08-02 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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1LO5
 | | Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II | | Descriptor: | HLA class II histocompatibility antigen, DR alpha chain, DR-1 beta chain, ... | | Authors: | Petersson, K, Thunnissen, M, Forsberg, G, Walse, B. | | Deposit date: | 2002-05-06 | | Release date: | 2002-12-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal Structure of a SEA Variant in Complex with MHC Class II Reveals the Ability of SEA to Crosslink MHC Molecules
Structure, 10, 2002
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1I4X
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