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PDB: 37 results

2WFX
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BU of 2wfx by Molmil
Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium
Descriptor: CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ...
Authors:Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
2WG3
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BU of 2wg3 by Molmil
Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, ...
Authors:Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C.
Deposit date:2009-04-15
Release date:2009-06-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
3HO5
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BU of 3ho5 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex
Descriptor: CALCIUM ION, Hedgehog-interacting protein, Sonic hedgehog protein, ...
Authors:Hymowitz, S.G, Bosanac, I.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
7E2I
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BU of 7e2i by Molmil
Cryo-EM structure of hDisp1NNN-ShhN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1, ...
Authors:Li, W, Wang, L, Gong, X.
Deposit date:2021-02-05
Release date:2021-12-08
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
2IBG
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BU of 2ibg by Molmil
Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog
Descriptor: CG9211-PA, PHOSPHATE ION, Protein hedgehog
Authors:McLellan, J.S, Leahy, D.J.
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3D1M
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BU of 3d1m by Molmil
Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO
Descriptor: CALCIUM ION, Cell adhesion molecule, Sonic hedgehog protein, ...
Authors:McLellan, J.S, Leahy, D.J.
Deposit date:2008-05-06
Release date:2008-09-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
Nature, 455, 2008
6TD6
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BU of 6td6 by Molmil
Structure of Drosophila melanogaster Dispatched bound to a modified Hedgehog ligand, HhN-C85II
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein dispatched, ...
Authors:Korkhov, V.M, Cannac, F.
Deposit date:2019-11-07
Release date:2020-06-03
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.76 Å)
Cite:Cryo-EM structure of the Hedgehog release protein Dispatched.
Sci Adv, 6, 2020
3N1G
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BU of 3n1g by Molmil
Crystal structure of DhhN bound to BOCFn3
Descriptor: Brother of CDO, CALCIUM ION, Desert hedgehog protein, ...
Authors:Kavran, J.M, Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1P
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BU of 3n1p by Molmil
Crystal Structure of IhhN bound to BOCFn3
Descriptor: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
Authors:Kavran, J.M, Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1Q
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BU of 3n1q by Molmil
Crystal Structure of DhhN bound to CDOFn3
Descriptor: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ...
Authors:Kavran, J.M, Leahy, D.J.
Deposit date:2010-05-16
Release date:2010-06-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1F
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BU of 3n1f by Molmil
Crystal Structure of IhhN bound to CDOFn3
Descriptor: CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ...
Authors:Kavran, J.M, Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
3N1M
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BU of 3n1m by Molmil
Crystal Structure of IhhN bound to BOCFn3
Descriptor: Brother of CDO, CALCIUM ION, Indian hedgehog protein, ...
Authors:Kavran, J.M, Leahy, D.J.
Deposit date:2010-05-15
Release date:2010-06-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner.
J.Biol.Chem., 285, 2010
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