8G9O
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![BU of 8g9o by Molmil](/molmil-images/mine/8g9o) | Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G99
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![BU of 8g99 by Molmil](/molmil-images/mine/8g99) | Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G9F
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![BU of 8g9f by Molmil](/molmil-images/mine/8g9f) | Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8G9L
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![BU of 8g9l by Molmil](/molmil-images/mine/8g9l) | DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-02-21 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8HPA
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![BU of 8hpa by Molmil](/molmil-images/mine/8hpa) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form | Descriptor: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | Authors: | Xu, Y, Wu, Y, Zhang, Y, Fan, R, Yang, Y, Li, D, Yang, B, Zhang, Z, Dong, C. | Deposit date: | 2022-12-12 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structure of DNA replication machinery from human monkeypox virus To Be Published
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3NAE
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![BU of 3nae by Molmil](/molmil-images/mine/3nae) | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | Deposit date: | 2010-06-01 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
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3KD5
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![BU of 3kd5 by Molmil](/molmil-images/mine/3kd5) | |
3KD1
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![BU of 3kd1 by Molmil](/molmil-images/mine/3kd1) | |
3QER
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![BU of 3qer by Molmil](/molmil-images/mine/3qer) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dATP Opposite Difluorotoluene Nucleoside | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Xia, S, Konigsberg, W.H, Wang, J. | Deposit date: | 2011-01-20 | Release date: | 2012-01-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
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3NE6
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![BU of 3ne6 by Molmil](/molmil-images/mine/3ne6) | RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Wang, M, Wang, J, Konigsberg, W.H. | Deposit date: | 2010-06-08 | Release date: | 2011-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
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3NGI
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![BU of 3ngi by Molmil](/molmil-images/mine/3ngi) | RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | Authors: | Wang, M, Wang, J, Konigsberg, W.H. | Deposit date: | 2010-06-11 | Release date: | 2011-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.886 Å) | Cite: | Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
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3K5M
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![BU of 3k5m by Molmil](/molmil-images/mine/3k5m) | Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-07 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K59
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![BU of 3k59 by Molmil](/molmil-images/mine/3k59) | Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-06 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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3K5O
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![BU of 3k5o by Molmil](/molmil-images/mine/3k5o) | Crystal structure of E.coli Pol II | Descriptor: | DNA polymerase II | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-07 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K57
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![BU of 3k57 by Molmil](/molmil-images/mine/3k57) | Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-06 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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3K5N
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![BU of 3k5n by Molmil](/molmil-images/mine/3k5n) | Crystal structure of E.coli Pol II-abasic DNA binary complex | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-07 | Release date: | 2010-02-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3K58
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![BU of 3k58 by Molmil](/molmil-images/mine/3k58) | Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex | Descriptor: | DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-06 | Release date: | 2010-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
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3K5L
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![BU of 3k5l by Molmil](/molmil-images/mine/3k5l) | Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | Authors: | Yang, W, Wang, F. | Deposit date: | 2009-10-07 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
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3QEX
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![BU of 3qex by Molmil](/molmil-images/mine/3qex) | |
3QNO
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![BU of 3qno by Molmil](/molmil-images/mine/3qno) | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite 3tCo | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Polymerase, ... | Authors: | Xia, S, Wang, M, Wang, J, Konigsberg, W.H. | Deposit date: | 2011-02-08 | Release date: | 2012-03-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Biochemistry, 51, 2012
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3QEP
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![BU of 3qep by Molmil](/molmil-images/mine/3qep) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | Authors: | Xia, S, Konigsberg, W.H, Wang, J. | Deposit date: | 2011-01-20 | Release date: | 2011-08-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. J.Am.Chem.Soc., 133, 2011
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3QEI
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![BU of 3qei by Molmil](/molmil-images/mine/3qei) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dCTP Opposite Difluorotoluene Nucleoside | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Xia, S, Konigsberg, W.H, Wang, J. | Deposit date: | 2011-01-20 | Release date: | 2012-01-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.178 Å) | Cite: | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
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3QNN
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![BU of 3qnn by Molmil](/molmil-images/mine/3qnn) | RB69 DNA Polymerase (Y567A) Ternary Complex with dGT Opposite 3tCo | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ... | Authors: | Xia, S, Wang, M, Wang, J, Konigsberg, W.H. | Deposit date: | 2011-02-08 | Release date: | 2012-02-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Biochemistry, 51, 2012
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3QEW
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![BU of 3qew by Molmil](/molmil-images/mine/3qew) | |
3QES
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![BU of 3qes by Molmil](/molmil-images/mine/3qes) | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dGTP Opposite Difluorotoluene Nucleoside | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | Authors: | Xia, S, Konigsberg, W.H, Wang, J. | Deposit date: | 2011-01-20 | Release date: | 2012-01-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue. Biochemistry, 51, 2012
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