3QER

RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dATP Opposite Difluorotoluene Nucleoside

Summary for 3QER

• Entry DOI: 10.2210/pdb3qer/pdb
• Related: 3QEI 3QEP 3QES 3QET 3QEV 3QEW 3QEX
• Descriptor: DNA polymerase, DNA (5'-D(P*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... (6 entities in total)
• Functional Keywords: difluorotoluene nucleoside, datp, triple mutant, transferase-dna complex, transferase/dna
• Biological source: Enterobacteria phage RB69 (Bacteriophage RB69); More
• Total number of polymer chains: 3
• Total formula weight: 114628.61

Authors

Xia, S.,Konigsberg, W.H.,Wang, J. (deposition date: 2011-01-20, release date: 2012-01-25, Last modification date: 2024-02-21)

• Primary citation: Xia, S.,Eom, S.H.,Konigsberg, W.H.,Wang, J.; Structural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide Residue.; Biochemistry, 51:1476-1485, 2012; PubMed: 22304682; DOI: 10.1021/bi2016487

Experimental method

X-RAY DIFFRACTION (1.96 Å)