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PDB: 35 results

6UUZ
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BU of 6uuz by Molmil
Structure of ACLY in the presence of citrate and CoA
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Xuepeng, W, Ronen, M.
Deposit date:2019-11-01
Release date:2020-01-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
7LJ9
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BU of 7lj9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-03-31
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
6UI9
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BU of 6ui9 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ACLY, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-09-30
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
6QFB
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BU of 6qfb by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2019-01-09
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6HXH
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BU of 6hxh by Molmil
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ...
Authors:Verstraete, K, Verschueren, K.
Deposit date:2018-10-17
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
Nature, 568, 2019
6UV5
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BU of 6uv5 by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-11-01
Release date:2019-12-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6POE
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BU of 6poe by Molmil
Structure of ACLY in complex with CoA
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-07-03
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6O0H
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BU of 6o0h by Molmil
Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate
Authors:Wei, J, Tong, L.
Deposit date:2019-02-16
Release date:2019-04-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Nature, 568, 2019
6POF
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BU of 6pof by Molmil
Structure of human ATP citrate lyase
Descriptor: ATP-citrate synthase
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-07-03
Release date:2020-01-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
6UIA
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BU of 6uia by Molmil
Structure of ATP citrate lyase with CoA in a partially open conformation
Descriptor: ATP-citrate synthase, COENZYME A
Authors:Wei, X, Marmorstein, R.
Deposit date:2019-09-30
Release date:2019-12-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
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