8BHL
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8EIU
| E. coli 70S ribosome with A-loop mutations U2554C and U2555C | Descriptor: | 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | Authors: | Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D. | Deposit date: | 2022-09-15 | Release date: | 2023-02-01 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.24 Å) | Cite: | Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome. Nucleic Acids Res., 51, 2023
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8YUO
| E. coli 70S ribosome complexed with P. putida tRNAIle2 at the A-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Shirouzu, M, Suzuki, T. | Deposit date: | 2024-03-27 | Release date: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (2.25 Å) | Cite: | A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nat.Chem.Biol., 2024
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7Z20
| 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia and a stalled filamin domain 5 nascent chain | Descriptor: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | Deposit date: | 2022-02-25 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.29 Å) | Cite: | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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8AKN
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome | Descriptor: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | Authors: | Koller, T.O, Morici, M, Wilson, D.N. | Deposit date: | 2022-07-30 | Release date: | 2023-03-08 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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8G6X
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8HSP
| E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and t6A37 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-20 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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7N1P
| Elongating 70S ribosome complex in a classical pre-translocation (PRE-C) conformation | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Holm, M, Schacherl, M, Natchiar, S.K, Altman, R.B, Spahn, C.M.T, Myasnikov, A.G, Blanchard, S.C. | Deposit date: | 2021-05-28 | Release date: | 2021-07-14 | Last modified: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.33 Å) | Cite: | Structural basis of early translocation events on the ribosome. Nature, 595, 2021
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8BF7
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7Y7G
| Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7PJS
| Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | Deposit date: | 2021-08-24 | Release date: | 2021-10-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Structural mechanism of GTPase-powered ribosome-tRNA movement Nat Commun, 12, 2021
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7S1H
| Wild-type Escherichia coli ribosome with antibiotic linezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2021-11-17 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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8BHP
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8YUP
| E. coli 70S ribosome complexed with P. putida tRNAIle2 and A4 mRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Shirouzu, M, Suzuki, T. | Deposit date: | 2024-03-28 | Release date: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (2.39 Å) | Cite: | A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nat.Chem.Biol., 2024
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7BL4
| in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Hilal, T, Nikolay, R, Spahn, C.M.T. | Deposit date: | 2021-01-18 | Release date: | 2021-05-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization. Mol.Cell, 81, 2021
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9FBV
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7O1A
| Cryo-EM structure of an Escherichia coli TnaC(R23F)-ribosome complex stalled in response to L-tryptophan | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | Authors: | van der Stel, A.X, Gordon, E.R, Sengupta, A, Martinez, A.K, Klepacki, D, Perry, T.N, Herrero del Valle, A, Vazquez-Laslop, N, Sachs, M.S, Cruz-Vera, L.R, Innis, C.A. | Deposit date: | 2021-03-29 | Release date: | 2021-09-01 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling. Nat Commun, 12, 2021
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8W51
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8HTZ
| E. coli 70S ribosome complexed with H. marismortui tRNA_Ile2 bearing agm2C34 in classical state | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-12-22 | Release date: | 2024-04-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
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8R8M
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8YUQ
| E. coli 70S ribosome complexed with P. putida tRNAIle2 and dA4 mRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Shirouzu, M, Suzuki, T. | Deposit date: | 2024-03-27 | Release date: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nat.Chem.Biol., 2024
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7Y7E
| Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7S1K
| Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Tsai, K, Stojkovic, V, Lee, D.J, Young, I.D, Szal, T, Vazquez-Laslop, N, Mankin, A.S, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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8YUS
| E. coli 70S ribosome complexed with P.putida tRNAIle2 and A(F)4 mRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Akiyama, N, Ishiguro, K, Shirouzu, M, Suzuki, T. | Deposit date: | 2024-03-27 | Release date: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | A tRNA modification with aminovaleramide facilitates AUA decoding in protein synthesis. Nat.Chem.Biol., 2024
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8IFB
| Dibekacin-bound E.coli 70S ribosome in the PURE system | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. | Deposit date: | 2023-02-17 | Release date: | 2024-02-14 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024
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