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PDB: 1640 件

8H7Q
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Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution
分子名称: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2022-10-20
公開日2023-10-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution
To Be Published
7EGQ
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BU of 7egq by Molmil
Co-transcriptional capping machineries in SARS-CoV-2 RTC: Coupling of N7-methyltransferase and 3'-5' exoribonuclease with polymerase reveals mechanisms for capping and proofreading
分子名称: Helicase, MAGNESIUM ION, Non-structural protein 10, ...
著者Yan, L.M, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y.
登録日2021-03-25
公開日2021-07-21
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading.
Cell, 184, 2021
3V5J
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BU of 3v5j by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 090
分子名称: 3-[4-(2-morpholin-4-ylethoxy)-2-(1~{H}-thieno[3,2-c]pyrazol-3-yl)-1~{H}-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
著者McLean, L.R, Zhang, Y.
登録日2011-12-16
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
2JOA
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BU of 2joa by Molmil
HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances
分子名称: Peptide H1-C1, Serine protease HTRA1
著者Runyon, S.T, Zhang, Y, Appleton, B.A, Sazinksy, S.L, Wu, P, Pan, B, Wiesmann, C, Skelton, N.J, Sidhu, S.S.
登録日2007-03-01
公開日2007-11-20
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
Protein Sci., 16, 2007
3UAX
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BU of 3uax by Molmil
Crystal structure of adenosine phosphorylase from Bacillus cereus complexed with inosine
分子名称: GLYCEROL, INOSINE, Purine nucleoside phosphorylase deoD-type, ...
著者Dessanti, P, Zhang, Y, Allegrini, S, Tozzi, M.G, Sgarrella, F, Ealick, S.E.
登録日2011-10-22
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
2M09
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BU of 2m09 by Molmil
Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition
分子名称: Splicing factor 1
著者Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A.
登録日2012-10-22
公開日2013-01-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res., 41, 2013
8H67
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type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution.
分子名称: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
著者Xiao, Y, Lu, M, Yu, C, Zhang, Y.
登録日2022-10-15
公開日2024-05-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
3V5L
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BU of 3v5l by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 542
分子名称: 3-[3-(4-methoxyphenyl)-2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
著者McLean, L.R, Zhang, Y.
登録日2011-12-16
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
3TH8
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BU of 3th8 by Molmil
Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063
分子名称: (2Z)-4-({3-[3-(hexyloxy)phenyl]propyl}amino)-2-hydroxy-4-oxobut-2-enoic acid, Undecaprenyl pyrophosphate synthase
著者Cao, R, Zhu, W, Zhang, Y, Oldfield, E.
登録日2011-08-18
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.114 Å)
主引用文献HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
ACS Med Chem Lett, 3, 2012
3UAY
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BU of 3uay by Molmil
Crystal structure of Bacillus cereus adenosine phosphorylase D204N mutant complexed with adenosine
分子名称: ADENOSINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ...
著者Dessanti, P, Zhang, Y, Allegrini, S, Tozzi, M.G, Sgarrella, F, Ealick, S.E.
登録日2011-10-22
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
7XPN
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BU of 7xpn by Molmil
Structure of the Spring Viraemia of Carp Virus Nucleoprotein
分子名称: Nucleoprotein
著者Wang, Z.X, Liu, B, Zhang, Y.A, Ouyang, S.Y.
登録日2022-05-04
公開日2023-05-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structure of the Spring Viraemia of Carp Virus Ribonucleoprotein Complex Reveals Its Assembly Mechanism and Application in Antiviral Drug Screening.
J.Virol., 97, 2023
7VCF
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BU of 7vcf by Molmil
Cryo-EM structure of Chlamydomonas TOC-TIC supercomplex
分子名称: 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ...
著者Wu, J, Yan, Z, Jin, Z, Zhang, Y.
登録日2021-09-02
公開日2022-11-30
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes.
Cell, 185, 2022
2H2M
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BU of 2h2m by Molmil
Solution Structure of the N-terminal domain of COMMD1 (Murr1)
分子名称: COMM domain-containing protein 1
著者Sommerhalter, M, Zhang, Y, Rosenzweig, A.C.
登録日2006-05-19
公開日2006-12-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of the COMMD1 N-terminal Domain.
J.Mol.Biol., 365, 2007
7EIZ
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BU of 7eiz by Molmil
Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading
分子名称: Helicase, MAGNESIUM ION, Non-structural protein 10, ...
著者Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y.
登録日2021-04-01
公開日2021-09-22
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY
主引用文献Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading
Cell, 184, 2021
2L9S
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BU of 2l9s by Molmil
Solution structure of Pf1 SID1-mSin3A PAH2 Complex
分子名称: PHD finger protein 12, Paired amphipathic helix protein Sin3a
著者Senthil Kumar, G, Xie, T, Zhang, Y, Radhakrishnan, I.
登録日2011-02-23
公開日2011-05-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the mSin3A PAH2-Pf1 SID1 Complex: A Mad1/Mxd1-Like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S Complex.
J.Mol.Biol., 408, 2011
7Y6I
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BU of 7y6i by Molmil
Cryo-EM structure of human sodium-chloride cotransporter
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q.
登録日2022-06-20
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Cryo-EM structure of the human sodium-chloride cotransporter NCC.
Sci Adv, 8, 2022
2M0G
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BU of 2m0g by Molmil
Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition
分子名称: Splicing factor 1, Splicing factor U2AF 65 kDa subunit
著者Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A.
登録日2012-10-25
公開日2013-01-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res., 41, 2013
3UAW
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BU of 3uaw by Molmil
Crystal structure of adenosine phosphorylase from Bacillus cereus complexed with adenosine
分子名称: ADENOSINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ...
著者Dessanti, P, Zhang, Y, Allegrini, S, Tozzi, M.G, Sgarrella, F, Ealick, S.E.
登録日2011-10-22
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase.
Acta Crystallogr.,Sect.D, 68, 2012
2GQD
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BU of 2gqd by Molmil
The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Miller, D.J, White, S.W, Zhang, Y.M, Rock, C.O.
登録日2006-04-20
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus
To be Published
2N1D
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BU of 2n1d by Molmil
Solution structure of the MRG15-MRGBP complex
分子名称: MRG/MORF4L-binding protein, Mortality factor 4-like protein 1
著者Xie, T, Zmysloski, A.M, Zhang, Y, Radhakrishnan, I.
登録日2015-03-27
公開日2015-05-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Multi-specificity of MRG Domains.
Structure, 23, 2015
7X8R
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BU of 7x8r by Molmil
Cryo-EM structure of the Boc5-bound hGLP-1R-Gs complex
分子名称: 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W.
登録日2022-03-14
公開日2022-06-29
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc.Natl.Acad.Sci.USA, 119, 2022
7X8S
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BU of 7x8s by Molmil
Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex
分子名称: 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-(2-methylpropanoylamino)phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W.
登録日2022-03-14
公開日2022-06-29
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GZG
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BU of 8gzg by Molmil
Cryo-EM structure of Synechocystis sp. PCC 6803 RPitc
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Shen, L.Q, You, L.L, Zhang, Y.
登録日2022-09-27
公開日2023-04-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Proc.Natl.Acad.Sci.USA, 2023
8GZH
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BU of 8gzh by Molmil
Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者You, L.L, Shen, L.Q, Zhang, Y.
登録日2022-09-27
公開日2023-04-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Proc.Natl.Acad.Sci.USA, 2023
8IXW
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BU of 8ixw by Molmil
Tilapia lake virus S8 segment
分子名称: Chains: A,B, selenourea
著者Wang, Z.X, Zhang, Y.A, Ouyang, S.Y.
登録日2023-04-03
公開日2024-04-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of tilapia lake virus S8 segment
To Be Published

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件を2024-07-24に公開中

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