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PDB: 1640 件

6DAO
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NahE WT selenomethionine
分子名称: Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-05-08
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
5X58
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Prefusion structure of SARS-CoV spike glycoprotein, conformation 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5B
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Prefusion structure of SARS-CoV spike glycoprotein, conformation 2
分子名称: Spike glycoprotein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2017-05-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X59
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Prefusion structure of MERS-CoV spike glycoprotein, three-fold symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5C
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Prefusion structure of MERS-CoV spike glycoprotein, conformation 1
分子名称: S protein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2017-05-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
5X5F
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Prefusion structure of MERS-CoV spike glycoprotein, conformation 2
分子名称: S protein
著者Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F.
登録日2017-02-15
公開日2017-05-03
最終更新日2017-05-24
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Nat Commun, 8, 2017
4MZ7
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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
著者Zhu, C, Gao, W, Zhao, K, Qin, X, Zhang, Y, Peng, X, Zhang, L, Dong, Y, Zhang, W, Li, P, Wei, W, Gong, Y, Yu, X.F.
登録日2013-09-29
公開日2013-11-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Nat Commun, 4, 2013
1T9F
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Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function
分子名称: MALONATE ION, protein 1d10
著者Symersky, J, Li, S, Bunzel, R, Schormann, N, Luo, D, Huang, W.Y, Qiu, S, Gray, R, Zhang, Y, Arabashi, A, Lu, S, Luan, C.H, Tsao, J, DeLucas, L, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-05-16
公開日2004-05-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural genomics of Caenorhabditis elegans: Structure of a protein with unknown function.
To be Published
8IMZ
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Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map)
分子名称: MyoD family inhibitor domain-containing protein, Piezo-type mechanosensitive ion channel component 1
著者Zhou, Z, Ma, X, Lin, Y, Cheng, D, Bavi, N, Li, J.V, Sutton, D, Yao, M, Harvey, N, Corry, B, Zhang, Y, Cox, C.D.
登録日2023-03-07
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.
Science, 381, 2023
1P9Z
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The Solution Structure of Antifungal Peptide Distinct With a Five-disulfide Motif from Eucommia ulmoides Oliver
分子名称: Eucommia Antifungal peptide 2
著者Huang, R.H, Xiang, Y, Tu, G.Z, Zhang, Y, Wang, D.C.
登録日2003-05-13
公開日2004-05-25
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Solution Structure of Eucommia Antifungal Peptide: A Novel Structural Model Distinct with a Five-Disulfide Motif.
Biochemistry, 43, 2004
8XZG
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Cryo-EM structure of the [Pyr1]-apelin-13-bound human APLNR-Gi complex
分子名称: Apelin receptor, Apelin-13, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Wang, W, Ji, S, Zhang, Y.
登録日2024-01-21
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-based design of non-hypertrophic apelin receptor modulator.
Cell, 187, 2024
3NPH
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Crystal structure of the pfam00427 domain from Synechocystis sp. PCC 6803
分子名称: Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 2
著者Gao, X, Chen, L, Wu, J.-W, Zhang, Y.-Z.
登録日2010-06-28
公開日2011-06-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Crystal structure of the N-terminal domain of linker L(R) and the assembly of cyanobacterial phycobilisome rods
Mol.Microbiol., 82, 2011
5Z9Y
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Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP
分子名称: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Thiazole synthase
著者Zhang, J, Zhang, B, Zhao, Y, Yang, X, Huang, M, Cui, P, Zhang, W, Li, J, Zhang, Y.
登録日2018-02-05
公開日2018-04-11
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Snapshots of catalysis: Structure of covalently bound substrate trapped in Mycobacterium tuberculosis thiazole synthase (ThiG).
Biochem. Biophys. Res. Commun., 497, 2018
1BZL
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CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH TRYPANOTHIONE, AND THE STRUCTURE-BASED DISCOVERY OF NEW NATURAL PRODUCT INHIBITORS
分子名称: BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE (OXIDIZED FORM)
著者Bond, C.S, Zhang, Y, Berriman, M, Cunningham, M, Fairlamb, A.H, Hunter, W.N.
登録日1998-11-02
公開日1999-11-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors.
Structure Fold.Des., 7, 1999
1M7E
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Crystal structure of the phosphotyrosine binding domain(PTB) of mouse Disabled 2(Dab2):implications for Reeling signaling
分子名称: Disabled homolog 2, NGYENPTYK peptide
著者Yun, M, Keshvara, L, Park, C.-G, Zhang, Y.-M, Dickerson, J.B, Zheng, J, Rock, C.O, Curran, T, Park, H.-W.
登録日2002-07-19
公開日2003-08-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of the Dab homology domains of mouse disabled 1 and 2
J.Biol.Chem., 278, 2003
1GX0
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - BETA-D-GALACTOSE COMPLEX
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Boix, E, Zhang, Y, Swaminathan, G.J, Brew, K, Acharya, K.R.
登録日2002-03-26
公開日2003-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GX4
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - N-ACETYL LACTOSAMINE COMPLEX
分子名称: GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ...
著者Boix, E, Zhang, Y, Swaminathan, G.J, Brew, K, Acharya, K.R.
登録日2002-03-27
公開日2003-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GWW
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - ALPHA-D-GLUCOSE COMPLEX
分子名称: MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ...
著者Boix, E, Zhang, Y, Swaminathan, G.J, Brew, K, Acharya, K.R.
登録日2002-03-26
公開日2003-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GWV
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - LACTOSE COMPLEX
分子名称: MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ...
著者Boix, E, Zhang, Y, Swaminathan, G.J, Brew, K, Acharya, K.R.
登録日2002-03-26
公開日2003-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
4LEJ
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Crystal Structure of the Korean pine (Pinus koraiensis) vicilin
分子名称: COPPER (II) ION, GLYCEROL, PHOSPHATE ION, ...
著者Jin, T.C, Wang, Y, Zhang, Y.Z.
登録日2013-06-25
公開日2014-01-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal Structure of Korean Pine ( Pinus koraiensis ) 7S Seed Storage Protein with Copper Ligands.
J.Agric.Food Chem., 62, 2014
2XNI
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Protein-ligand complex of a novel macrocyclic HCV NS3 protease inhibitor derived from amino cyclic boronates
分子名称: (1-{[(10-tert-butyl-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19,23,23a-tetradecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosin-7(3H)-yl)carbonyl]amino}-3-hydroxypropyl)(trihydroxy)borate(1-), MAGNESIUM ION, NS3 PROTEASE, ...
著者Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Zhou, Y, Li, Q, Plattner, J.J, Baker, S.J, Zhang, S, Kazmierski, W.M, Wright, L.L, Smith, G.K, Grimes, R.M, Crosby, R.M, Creech, K.L, Carballo, L.H, Slater, M.J, Jarvest, R.L, Thommes, P, Hubbard, J.A, Convery, M.A, Nassau, P.M, McDowell, W, Skarzynski, T.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, Pennicott, L.E, Zou, W, Wright, J.
登録日2010-08-02
公開日2011-08-17
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Novel Macrocyclic Hcv Ns3 Protease Inhibitors Derived from Alpha-Amino Cyclic Boronates.
Bioorg.Med.Chem.Lett., 20, 2010
1KLP
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The Solution Structure of Acyl Carrier Protein from Mycobacterium tuberculosis
分子名称: MEROMYCOLATE EXTENSION ACYL CARRIER PROTEIN
著者Wong, H.C, Liu, G, Zhang, Y.-M, Rock, C.O, Zheng, J.
登録日2001-12-12
公開日2002-06-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The solution structure of acyl carrier protein from Mycobacterium tuberculosis.
J.Biol.Chem., 277, 2002
1IDS
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X-RAY STRUCTURE ANALYSIS OF THE IRON-DEPENDENT SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.0 ANGSTROMS RESOLUTIONS REVEALS NOVEL DIMER-DIMER INTERACTIONS
分子名称: FE (III) ION, IRON SUPEROXIDE DISMUTASE
著者Cooper, J.B, Mcintyre, K, Wood, S.P, Zhang, Y, Young, D.
登録日1994-09-29
公開日1994-12-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure analysis of the iron-dependent superoxide dismutase from Mycobacterium tuberculosis at 2.0 Angstroms resolution reveals novel dimer-dimer interactions.
J.Mol.Biol., 246, 1995
4Q05
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Crystal structure of an esterase E25
分子名称: SODIUM ION, esterase E25
著者Li, P.Y, Li, C.Y, Zhang, Y.Z.
登録日2014-03-31
公開日2014-06-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for dimerization and catalysis of a novel esterase from the GTSAG motif subfamily of the bacterial hormone-sensitive lipase family
J.Biol.Chem., 289, 2014
1AOG
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TRYPANOSOMA CRUZI TRYPANOTHIONE REDUCTASE (OXIDIZED FORM)
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MALEIC ACID, TRYPANOTHIONE REDUCTASE
著者Bond, C.S, Zhang, Y, Hunter, W.N.
登録日1997-07-03
公開日1997-09-17
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of trypanothione reductase from the human pathogen Trypanosoma cruzi at 2.3 A resolution.
Protein Sci., 5, 1996

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