2MHA
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![BU of 2mha by Molmil](/molmil-images/mine/2mha) | CRYSTAL STRUCTURE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I H-2KB MOLECULE CONTAINING A SINGLE VIRAL PEPTIDE: IMPLICATIONS FOR PEPTIDE BINDING AND T-CELL RECEPTOR RECOGNITION | 分子名称: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H-2KB) (ALPHA CHAIN), VIRAL OCTAPEPTIDE ARG-GLY-TYR-VAL-TYR-GLN-GLY-LEU | 著者 | Zhang, W, Young, A.C.M, Imarai, M, Nathenson, S.G, Sacchettini, J.C. | 登録日 | 1993-07-21 | 公開日 | 1993-10-31 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc.Natl.Acad.Sci.USA, 89, 1992
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5TGP
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![BU of 5tgp by Molmil](/molmil-images/mine/5tgp) | |
7VJT
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![BU of 7vjt by Molmil](/molmil-images/mine/7vjt) | Crystal Structure of Mtb Pks13-TE in complex with inhibitor coumestan derivative 8 | 分子名称: | 3,8-bis(oxidanyl)-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one, Polyketide synthase Pks13 (Termination polyketide synthase) | 著者 | Zhang, W, Wang, S.S, Yu, L.F. | 登録日 | 2021-09-28 | 公開日 | 2022-09-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structure-Based Optimization of Coumestan Derivatives as Polyketide Synthase 13-Thioesterase(Pks13-TE) Inhibitors with Improved hERG Profiles for Mycobacterium tuberculosis Treatment. J.Med.Chem., 65, 2022
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3FFM
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3TO8
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![BU of 3to8 by Molmil](/molmil-images/mine/3to8) | Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L) | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Heterogeneous nuclear ribonucleoprotein L, ... | 著者 | Zhang, W.J, Zeng, F.X, Liu, Y.W, Zhao, Y, Niu, L.W, Teng, M.K, Li, X. | 登録日 | 2011-09-04 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of the two C-terminal RRM domains of heterogeneous nuclear ribonucleoprotein L (hnRNP L) To be Published
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3J0B
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![BU of 3j0b by Molmil](/molmil-images/mine/3j0b) | cryo-EM reconstruction of West Nile virus | 分子名称: | envelope glycoprotein E | 著者 | Zhang, W, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2011-06-15 | 公開日 | 2012-12-19 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (10.3 Å) | 主引用文献 | Membrane curvature in flaviviruses. J.Struct.Biol., 183, 2013
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7UFK
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![BU of 7ufk by Molmil](/molmil-images/mine/7ufk) | Crystal structure of chimeric omicron RBD (strain BA.2) complexed with human ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | 登録日 | 2022-03-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
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7UFL
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![BU of 7ufl by Molmil](/molmil-images/mine/7ufl) | Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | 登録日 | 2022-03-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
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3TJM
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![BU of 3tjm by Molmil](/molmil-images/mine/3tjm) | Crystal Structure of the Human Fatty Acid Synthase Thioesterase Domain with an Activate Site-Specific Polyunsaturated Fatty Acyl Adduct | 分子名称: | Fatty acid synthase, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate | 著者 | Zhang, W, Zheng, F, Florante, A.Q. | 登録日 | 2011-08-24 | 公開日 | 2011-09-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid. Proc.Natl.Acad.Sci.USA, 108, 2011
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4V4Q
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![BU of 4v4q by Molmil](/molmil-images/mine/4v4q) | Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. | 登録日 | 2005-08-30 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | 主引用文献 | Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
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4V54
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![BU of 4v54 by Molmil](/molmil-images/mine/4v54) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF). | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | 登録日 | 2007-06-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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6PWW
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![BU of 6pww by Molmil](/molmil-images/mine/6pww) | Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | 分子名称: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | 登録日 | 2019-07-23 | 公開日 | 2019-12-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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1THD
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![BU of 1thd by Molmil](/molmil-images/mine/1thd) | COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION | 分子名称: | Major envelope protein E | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2004-06-01 | 公開日 | 2004-09-28 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein Structure, 12, 2004
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4V49
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![BU of 4v49 by Molmil](/molmil-images/mine/4v49) | Crystal Structure of a Streptomycin Dependent Ribosome from E. Coli 70S Ribosome. | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ... | 著者 | Vila-Sanjurjo, A, Ridgeway, W.K, Seymaner, V, Zhang, W, Santoso, S, Yu, K, Cate, J.H.D. | 登録日 | 2003-06-13 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (8.7 Å) | 主引用文献 | X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli Proc.Natl.Acad.Sci.USA, 100, 2003
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1TGE
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![BU of 1tge by Molmil](/molmil-images/mine/1tge) | The structure of immature Dengue virus at 12.5 angstrom | 分子名称: | envelope glycoprotein | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2004-05-28 | 公開日 | 2004-09-28 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12.5 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein. Structure, 12, 2004
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1SWV
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![BU of 1swv by Molmil](/molmil-images/mine/1swv) | Crystal structure of the D12A mutant of phosphonoacetaldehyde hydrolase complexed with magnesium | 分子名称: | MAGNESIUM ION, phosphonoacetaldehyde hydrolase | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2004-03-30 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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1TG8
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![BU of 1tg8 by Molmil](/molmil-images/mine/1tg8) | The structure of Dengue virus E glycoprotein | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, envelope glycoprotein | 著者 | Zhang, Y, Zhang, W, Ogata, S, Clements, D, Strauss, J.H, Baker, T.S, Rossmann, M.G. | 登録日 | 2004-05-28 | 公開日 | 2004-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Conformational changes of the flavivirus e glycoprotein Structure, 12, 2004
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1SWW
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![BU of 1sww by Molmil](/molmil-images/mine/1sww) | Crystal structure of the phosphonoacetaldehyde hydrolase D12A mutant complexed with magnesium and substrate phosphonoacetaldehyde | 分子名称: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE, phosphonoacetaldehyde hydrolase | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | 登録日 | 2004-03-30 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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4V50
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![BU of 4v50 by Molmil](/molmil-images/mine/4v50) | Crystal Structure of Ribosome with messenger RNA and the Anticodon stem-loop of P-site tRNA. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Berk, V, Zhang, W, Pai, R.D, Cate, J.H.D. | 登録日 | 2006-08-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural basis for mRNA and tRNA positioning on the ribosome. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4V5Y
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![BU of 4v5y by Molmil](/molmil-images/mine/4v5y) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF). | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | 登録日 | 2007-06-19 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (4.45 Å) | 主引用文献 | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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4V53
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![BU of 4v53 by Molmil](/molmil-images/mine/4v53) | Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin. | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ... | 著者 | Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. | 登録日 | 2007-06-16 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.54 Å) | 主引用文献 | Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
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9ERY
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![BU of 9ery by Molmil](/molmil-images/mine/9ery) | Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | 分子名称: | 5-[[5-[[2-[bis(fluoranyl)methyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]methoxy]-2-[(2-hydroxyethylamino)methyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1, SULFATE ION | 著者 | Plewka, J, Magiera-Mularz, K, Zhang, W. | 登録日 | 2024-03-25 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-L1 inhibitors Eur.J.Med.Chem., 2024
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6J1U
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![BU of 6j1u by Molmil](/molmil-images/mine/6j1u) | influenza virus nucleoprotein with a specific inhibitor | 分子名称: | Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide | 著者 | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | 登録日 | 2018-12-29 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle. J.Virol., 95, 2021
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3EWT
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![BU of 3ewt by Molmil](/molmil-images/mine/3ewt) | Crystal Structure of calmodulin complexed with a peptide | 分子名称: | CALCIUM ION, Calmodulin, Tumor necrosis factor receptor superfamily member 6 | 著者 | Jiang, T, Cao, P, Gong, Y, Yu, H.J, Gui, W.J, Zhang, W.T. | 登録日 | 2008-10-16 | 公開日 | 2009-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights into the mechanism of calmodulin binding to death receptors. Acta Crystallogr.,Sect.D, 70, 2014
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4QY1
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![BU of 4qy1 by Molmil](/molmil-images/mine/4qy1) | Structure of H10 from human-infecting H10N8 in complex with avian receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F. | 登録日 | 2014-07-23 | 公開日 | 2015-01-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | 主引用文献 | Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus Nat Commun, 6, 2015
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