2DLL
 
 | | Solution structure of the IRF domain of human interferon regulator factors 4 | | Descriptor: | Interferon regulatory factor 4 | | Authors: | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-20 | | Release date: | 2006-10-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the IRF domain of human interferon regulator factors 4
To be published
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2DLM
 | | Solution structure of the first SH3 domain of human vinexin | | Descriptor: | Vinexin | | Authors: | Zhang, H.P, Izumi, K, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-04-20 | | Release date: | 2006-10-20 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first SH3 domain of human vinexin
To be published
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4PV5
 | | Crystal structure of mouse glyoxalase I in complexed with 18-beta-glycyrrhetinic acid | | Descriptor: | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, Lactoylglutathione lyase, ZINC ION | | Authors: | Zhang, H, Zhai, J, Zhang, L.P, Zhao, Y.N, Li, C, Hu, X.P. | | Deposit date: | 2014-03-15 | | Release date: | 2015-03-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for 18-beta-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor
Acta Pharmacol.Sin., 36, 2015
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2EBQ
 | | Solution structure of the second zf-RanBP domain from human Nuclear pore complex protein Nup153 | | Descriptor: | Nuclear pore complex protein Nup153, ZINC ION | | Authors: | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-09 | | Release date: | 2007-08-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the second zf-RanBP domain from human Nuclear pore complex protein Nup153
To be published
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2EBV
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2EBZ
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2EBP
 | | Solution structure of the SH3 domain from human SAM and SH3 domain containing protein 1 | | Descriptor: | SAM and SH3 domain-containing protein 1 | | Authors: | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-09 | | Release date: | 2007-08-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SH3 domain from human SAM and SH3 domain containing protein 1
To be published
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2EQG
 | | Solution structure of the first A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 | | Descriptor: | Tumor necrosis factor, alpha-induced protein 3, ZINC ION | | Authors: | Zhang, H.P, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-30 | | Release date: | 2007-10-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the first A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
To be published
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2EC1
 | | Solution structure of the RanBD1 domain from human Nucleoporin 50 kDa | | Descriptor: | Nucleoporin 50 kDa | | Authors: | Zhang, H.P, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-09 | | Release date: | 2007-08-14 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the RanBD1 domain from human Nucleoporin 50 kDa
To be published
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2EBR
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2EQR
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2EC4
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1TDN
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2EQF
 | | Solution structure of the 7th A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 | | Descriptor: | Tumor necrosis factor, alpha-induced protein 3, ZINC ION | | Authors: | Zhang, H.P, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-30 | | Release date: | 2007-10-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 7th A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
To be Published
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2EQE
 | | Solution structure of the fourth A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 | | Descriptor: | Tumor necrosis factor, alpha-induced protein 3, ZINC ION | | Authors: | Zhang, H.P, Nagasima, T, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-30 | | Release date: | 2007-10-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the fourth A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
To be Published
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1TDO
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1TDK
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1OD2
 | | Acetyl-CoA Carboxylase Carboxyltransferase Domain | | Descriptor: | ACETYL COENZYME *A, ACETYL-COENZYME A CARBOXYLASE, ADENINE | | Authors: | Zhang, H, Yang, Z, Shen, Y, Tong, L. | | Deposit date: | 2003-02-12 | | Release date: | 2003-04-03 | | Last modified: | 2018-06-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase.
Science, 299, 2003
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8J9A
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8FK2
 | | The N-terminal VicR from Streptococcus mutans | | Descriptor: | Putative response regulator CovR VicR-like protein | | Authors: | Zhang, H, Wu, H. | | Deposit date: | 2022-12-20 | | Release date: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator.
Mbio, 14, 2023
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3NSQ
 | | Crystal structure of tetrameric RXRalpha-LBD complexed with antagonist danthron | | Descriptor: | 1,8-dihydroxyanthracene-9,10-dione, Retinoid X receptor, alpha | | Authors: | Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. | | Deposit date: | 2010-07-02 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
J.Biol.Chem., 286, 2011
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3NSP
 | | Crystal structure of tetrameric RXRalpha-LBD | | Descriptor: | Retinoid X receptor, alpha | | Authors: | Zhang, H, Hu, T, Li, L, Zhou, R, Chen, L, Hu, L, Jiang, H, Shen, X. | | Deposit date: | 2010-07-02 | | Release date: | 2010-11-17 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
J.Biol.Chem., 286, 2011
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4HDB
 | | Crystal Structure of HIV-1 protease mutants D30N complexed with inhibitor GRL-0519 | | Descriptor: | (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, HIV-1 Protease, ... | | Authors: | Zhang, H, Wang, Y.-F, Shen, C.H, Agniswamy, J, Weber, I.T. | | Deposit date: | 2012-10-02 | | Release date: | 2013-08-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease.
J.Med.Chem., 56, 2013
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6CKO
 | | Crystal structure of an AF10 fragment | | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10, ... | | Authors: | Zhang, H, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | Deposit date: | 2018-02-28 | | Release date: | 2018-03-21 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.
Genes Dev., 32, 2018
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5ZGE
 | | Crystal structure of NDM-1 at pH5.5 (Bis-Tris) in complex with hydrolyzed ampicillin | | Descriptor: | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... | | Authors: | Zhang, H, Hao, Q. | | Deposit date: | 2018-03-08 | | Release date: | 2018-08-22 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1.
Antimicrob. Agents Chemother., 62, 2018
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