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PDB: 888 件
2F58
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BU of 2f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE)
分子名称: 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ...
著者Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
登録日1998-10-23
公開日1999-02-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
1DBK
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BU of 1dbk by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
分子名称: 5-BETA-ANDROSTANE-3,17-DIONE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
著者Arevalo, J.H, Wilson, I.A.
登録日1993-08-24
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
1DBJ
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BU of 1dbj by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
分子名称: AETIOCHOLANOLONE, IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN)
著者Arevalo, J.H, Wilson, I.A.
登録日1993-08-24
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
1DBM
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BU of 1dbm by Molmil
MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY
分子名称: IGG1-KAPPA DB3 FAB (HEAVY CHAIN), IGG1-KAPPA DB3 FAB (LIGHT CHAIN), PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE
著者Arevalo, J.H, Wilson, I.A.
登録日1993-08-24
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of crossreactivity and the limits of antibody-antigen complementarity.
Nature, 365, 1993
4ZCJ
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BU of 4zcj by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA1 Cys30, HA2 Cys47 mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Lee, P.S, Wilson, I.A.
登録日2015-04-16
公開日2015-05-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer.
J.Virol., 89, 2015
5AWN
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BU of 5awn by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab
分子名称: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab
著者Lee, J.H, Wilson, I.A, Ward, A.B.
登録日2015-07-06
公開日2015-11-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.887 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
5IF0
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BU of 5if0 by Molmil
Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.44 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, PHOSPHATE ION, ...
著者Sarkar, A, Wilson, I.A.
登録日2016-02-25
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5ILT
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BU of 5ilt by Molmil
Crystal structure of bovine Fab A01
分子名称: bovine Fab A01 heavy chain, bovine Fab A01 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2016-03-04
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5IDL
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BU of 5idl by Molmil
Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT8
著者Julien, J.P, Ereno-Orbea, J, Jardine, J.G, Schief, W.R, Wilson, I.A.
登録日2016-02-24
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IES
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BU of 5ies by Molmil
Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.16 A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, ...
著者Sarkar, A, Wilson, I.A.
登録日2016-02-25
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5IFA
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BU of 5ifa by Molmil
Crystal structure of unbound VRC01c-HuGL2 Fab from an HIV-1 naive donor at 1.82 A
分子名称: GLYCEROL, PENTAETHYLENE GLYCOL, SULFATE ION, ...
著者Sarkar, A, Wilson, I.A.
登録日2016-02-25
公開日2016-04-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.821 Å)
主引用文献HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen.
Science, 351, 2016
5CJQ
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BU of 5cjq by Molmil
Crystal structure of a trimeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
分子名称: CR9114 heavy chain, CR9114 light chain, Designed influenza hemagglutinin stem #4900, ...
著者Zhu, X, Wilson, I.A.
登録日2015-07-14
公開日2015-09-09
最終更新日2015-09-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
5IJV
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BU of 5ijv by Molmil
Crystal structure of bovine Fab E03
分子名称: bovine Fab E03 heavy chain, bovine Fab E03 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2016-03-02
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
5JOR
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BU of 5jor by Molmil
Crystal structure of unbound anti-glycan antibody Fab14.22 at 2.2 A
分子名称: Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ...
著者Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A.
登録日2016-05-02
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.206 Å)
主引用文献T cells control the generation of nanomolar-affinity anti-glycan antibodies.
J. Clin. Invest., 127, 2017
5HZQ
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BU of 5hzq by Molmil
Crystal structure of cellular retinoic acid binding protein 2 (CRABP2)-aryl fluorosulfate covalent conjugate
分子名称: 4'-[(3,6,9,12-tetraoxapentadec-14-yn-1-yl)oxy][1,1'-biphenyl]-4-yl sulfurofluoridate, Cellular retinoic acid-binding protein 2, GLYCEROL
著者Chen, W, Mortenson, D.E, Wilson, I.A, Kelly, J.W.
登録日2016-02-02
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.
J.Am.Chem.Soc., 138, 2016
5C7K
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BU of 5c7k by Molmil
Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ...
著者Kong, L, Stanfield, R.L, Wilson, I.A.
登録日2015-06-24
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.6019 Å)
主引用文献Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
5JS9
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BU of 5js9 by Molmil
Uncleaved prefusion optimized gp140 trimer with an engineered 8-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A.
登録日2016-05-07
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (6.918 Å)
主引用文献Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.
Nat Commun, 7, 2016
5JOP
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BU of 5jop by Molmil
Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A
分子名称: Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ...
著者Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A.
登録日2016-05-02
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献T cells control the generation of nanomolar-affinity anti-glycan antibodies.
J. Clin. Invest., 127, 2017
5JSA
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BU of 5jsa by Molmil
Uncleaved prefusion optimized gp140 trimer with an engineered 10-residue HR1 turn bound to broadly neutralizing antibodies 8ANC195 and PGT128
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A.
登録日2016-05-07
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (6.308 Å)
主引用文献Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.
Nat Commun, 7, 2016
5BZD
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BU of 5bzd by Molmil
Crystal Structure of PCDN-27A, an antibody from the PCDN family of HIV-1 antibodies
分子名称: 5G8 HIV Antibody heavy chain, 5G8 HIV Antibody light chain, GLYCEROL
著者Garces, F, WILSON, I.A.
登録日2015-06-11
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Immunity, 44, 2016
5BZW
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BU of 5bzw by Molmil
Crystal Structure of PCDN-27B, an antibody from the PCDN family of HIV-1 antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B3 HIV Antibody heavy chain, 2B3 HIV Antibody light chain, ...
著者Garces, F, WILSON, I.A.
登録日2015-06-11
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch.
Immunity, 44, 2016
5CCK
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BU of 5cck by Molmil
Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC315 Fab
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Antibody 3BC315 Fab heavy chain, Antibody 3BC315 Fab light chain
著者Lee, J.H, Ward, A.B, Wilson, I.A.
登録日2015-07-02
公開日2015-10-07
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike.
Nat Commun, 6, 2015
5CEX
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BU of 5cex by Molmil
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
分子名称: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
著者Garces, F, Wilson, I.A.
登録日2015-07-07
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CJS
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BU of 5cjs by Molmil
Crystal structure of a monomeric influenza hemagglutinin stem in complex with an broadly neutralizing antibody CR9114
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 heavy chain, CR9114 light chain, ...
著者Zhu, X, Wilson, I.A.
登録日2015-07-15
公開日2015-09-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen.
Science, 349, 2015
2KTS
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BU of 2kts by Molmil
NMR structure of the protein NP_415897.1
分子名称: Heat shock protein hslJ
著者Serrano, P, Jaudzems, K, Geralt, M, Horst, R, Wuthrich, K, Wilson, I.A, Joint Center for Structural Genomics (JCSG)
登録日2010-02-06
公開日2010-02-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR structure of the protein NP_415897.1
To be Published

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