4FEX
 
 | | Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor tyrphostin AG1478 | | 分子名称: | ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, KANAMYCIN A, ... | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-05-30 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
Biochem.J., 454, 2013
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3BNI
 | | Crystal structure of TetR-family transcriptional regulator from Streptomyces coelicolor | | 分子名称: | Putative TetR-family transcriptional regulator, TETRAETHYLENE GLYCOL | | 著者 | Osipiuk, J, Xu, X, Gu, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-12-14 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray crystal structure of TetR-family transcriptional regulator from Streptomyces coelicolor.
To be Published
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2Q24
 | | Crystal structure of TetR transcriptional regulator SCO0520 from Streptomyces coelicolor | | 分子名称: | ACETATE ION, CHLORIDE ION, Putative tetR family transcriptional regulator | | 著者 | Cymborowski, M, Chruszcz, M, Koclega, K.D, Filippova, E.V, Xu, X, Gu, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-05-25 | | 公開日 | 2007-07-03 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of a putative transcriptional regulator SCO0520 from Streptomyces coelicolor A3(2) reveals an unusual dimer among TetR family proteins.
J.Struct.Funct.Genom., 12, 2011
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3D3R
 | | Crystal structure of the hydrogenase assembly chaperone HypC/HupF family protein from Shewanella oneidensis MR-1 | | 分子名称: | Hydrogenase assembly chaperone hypC/hupF | | 著者 | Kim, Y, Skarina, T, Onopriyenko, O, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-05-12 | | 公開日 | 2008-05-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of the Hydrogenase Assembly Chaperone HypC/HupF Family Protein from Shewanella oneidensis MR-1.
To be Published
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2Q16
 | | Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP | | 分子名称: | CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ... | | 著者 | Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F. | | 登録日 | 2007-05-23 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
J.Mol.Biol., 374, 2007
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4FEV
 | | Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP1 | | 分子名称: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | | 著者 | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-05-30 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance.
Biochem.J., 454, 2013
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4H5G
 | | Crystal structure of an amino acid ABC transporter substrate-binding protein from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine, form 2 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ARGININE, ... | | 著者 | Stogios, P.J, Wawrzak, Z, Kudritska, M, Minasov, G, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-09-18 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of an amino acid ABC transporter substrate-binding protein from Streptococcus pneumoniae Canada MDR_19A bound to L-arginine, form 2
TO BE PUBLISHED
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3DTZ
 | | Crystal structure of Putative Chlorite dismutase TA0507 | | 分子名称: | FORMIC ACID, Putative Chlorite dismutase TA0507 | | 著者 | Chang, C, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-07-16 | | 公開日 | 2008-08-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Crystal structure of Putative Chlorite dismutase TA0507
To be Published
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4E8O
 | | Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ih from Acinetobacter baumannii | | 分子名称: | Aac(6')-Ih protein, CHLORIDE ION | | 著者 | Stogios, P.J, Minasov, G, Dong, A, Evdokimova, E, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-20 | | 公開日 | 2012-04-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.138 Å) | | 主引用文献 | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
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2PPX
 | | Crystal structure of a HTH XRE-family like protein from Agrobacterium tumefaciens | | 分子名称: | GLYCEROL, SULFATE ION, Uncharacterized protein Atu1735 | | 著者 | Cuff, M.E, Skarina, T, Onopriyenko, O, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-04-30 | | 公開日 | 2007-05-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a HTH XRE-family like protein from Agrobacterium tumefaciens.
TO BE PUBLISHED
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4ECL
 | | Crystal structure of the cytoplasmic domain of vancomycin resistance serine racemase VanTg | | 分子名称: | CHLORIDE ION, SULFATE ION, Serine racemase | | 著者 | Stogios, P.J, Wawrzak, Z, Minasov, G, Evdokimova, E, Egorova, O, Cosme, J, Di Leo, R, Krishnamoorthy, M, Meziane-Cherif, D, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-26 | | 公開日 | 2012-04-18 | | 最終更新日 | 2016-06-01 | | 実験手法 | X-RAY DIFFRACTION (2.017 Å) | | 主引用文献 | Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.
MBio, 6, 2015
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3DNH
 | | The crystal structure of the protein Atu2129 (unknown function) from Agrobacterium tumefaciens str. C58 | | 分子名称: | uncharacterized protein Atu2129 | | 著者 | Tan, K, Xu, X, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-07-02 | | 公開日 | 2008-09-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | The crystal structure of the protein Atu2129 (unknown function) from Agrobacterium tumefaciens str. C58
To be Published
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3DT5
 | | C_terminal domain of protein of unknown function AF_0924 from Archaeoglobus fulgidus. | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Uncharacterized protein AF_0924 | | 著者 | Osipiuk, J, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-07-14 | | 公開日 | 2008-07-29 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | X-ray crystal structure of C_terminal domain of protein of unknown function AF_0924 from Archaeoglobus fulgidus.
To be Published
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4EVY
 | | Crystal structure of aminoglycoside antibiotic 6'-N-acetyltransferase AAC(6')-Ig from Acinetobacter haemolyticus in complex with tobramycin | | 分子名称: | Aminoglycoside N(6')-acetyltransferase type 1, CHLORIDE ION, POTASSIUM ION, ... | | 著者 | Stogios, P.J, Evdokimova, E, Minasov, G, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-04-26 | | 公開日 | 2012-05-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.768 Å) | | 主引用文献 | Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
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4EDP
 | | 1.85 Angstrom resolution crystal structure of an ABC transporter from Clostridium perfringens ATCC 13124 | | 分子名称: | ABC transporter, substrate-binding protein, ACETATE ION, ... | | 著者 | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-27 | | 公開日 | 2012-04-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | 1.85 Angstrom resolution crystal structure of an ABC transporter from Clostridium perfringens ATCC 13124
To be Published
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2QNU
 | | Crystal structure of PA0076 from Pseudomonas aeruginosa PAO1 at 2.05 A resolution | | 分子名称: | ACETATE ION, TRIETHYLENE GLYCOL, Uncharacterized protein PA0076 | | 著者 | Filippova, E.V, Chruszcz, M, Skarina, T, Kagan, O, Cymborowski, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-07-19 | | 公開日 | 2007-07-31 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of Pa0076 from Pseudomonas aeruginosa PAO1 at 2.05 A resolution.
To be Published
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4G65
 | | Potassium transporter peripheral membrane component (trkA) from Vibrio vulnificus | | 分子名称: | CHLORIDE ION, SULFATE ION, TETRAETHYLENE GLYCOL, ... | | 著者 | Filippova, E.V, Wawrzak, Z, Skarina, T, Onopriyenko, O, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-07-18 | | 公開日 | 2012-08-15 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Potassium transporter peripheral membrane component (trkA) from Vibrio vulnificus.
To be Published
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2PC6
 | | Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea | | 分子名称: | CALCIUM ION, Probable acetolactate synthase isozyme III (Small subunit), UNKNOWN LIGAND | | 著者 | Petkowski, J.J, Chruszcz, M, Zimmerman, M.D, Zheng, H, Cymborowski, M.T, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-03-29 | | 公開日 | 2007-04-10 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit.
Protein Sci., 16, 2007
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3D1P
 | | Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae | | 分子名称: | ACETATE ION, CHLORIDE ION, Putative thiosulfate sulfurtransferase YOR285W | | 著者 | Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-05-06 | | 公開日 | 2008-07-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae.
To be Published
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2R6O
 | | Crystal structure of putative diguanylate cyclase/phosphodiesterase from Thiobacillus denitrificans | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) | | 著者 | Chang, C, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-09-06 | | 公開日 | 2007-09-18 | | 最終更新日 | 2012-10-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.
J.Mol.Biol., 402, 2010
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2R8W
 | | The crystal structure of dihydrodipicolinate synthase (Atu0899) from Agrobacterium tumefaciens str. C58 | | 分子名称: | ACETATE ION, AGR_C_1641p, CHLORIDE ION | | 著者 | Tan, K, Dong, A, Xu, X, Gu, J, Zheng, H, Edwards, A.M, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-09-11 | | 公開日 | 2007-09-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of dihydrodipicolinate synthase (Atu0899) from Agrobacterium tumefaciens str. C58.
To be Published
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2R6I
 | | Crystal structure of Atu1473 protein, a putative chaperone from Agrobacterium tumefaciens | | 分子名称: | Uncharacterized protein Atu1473 | | 著者 | Osipiuk, J, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2007-09-05 | | 公開日 | 2007-09-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal structure of Atu1473 protein, a putative chaperone from Agrobacterium tumefaciens.
To be Published
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3EFE
 | | The crystal structure of the thiJ/pfpI family protein from Bacillus anthracis | | 分子名称: | SULFATE ION, ThiJ/pfpI family protein | | 著者 | Zhang, R, Xu, X, Cui, H, Savchenko, A, Edwards, A, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2008-09-08 | | 公開日 | 2008-09-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of the thiJ/pfpI family protein from Bacillus anthracis
To be Published
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3EEF
 | | Crystal structure of N-carbamoylsarcosine amidase from thermoplasma acidophilum | | 分子名称: | N-carbamoylsarcosine amidase related protein, ZINC ION | | 著者 | Luo, H.-B, Zheng, H, Chruszcz, M, Zimmerman, M.D, Skarina, T, Egorova, O, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-09-04 | | 公開日 | 2008-09-16 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum.
J.Struct.Biol., 169, 2010
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3E8X
 | | Putative NAD-dependent epimerase/dehydratase from Bacillus halodurans. | | 分子名称: | CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative NAD-dependent epimerase/dehydratase | | 著者 | Osipiuk, J, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-08-20 | | 公開日 | 2008-09-02 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray crystal structure of putative NAD-dependent epimerase/dehydratase from Bacillus halodurans.
To be Published
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