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PDB: 149 件

6R78
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BU of 6r78 by Molmil
Structure of IMP-13 metallo-beta-lactamase in apo form (loop closed)
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Beta-lactamase, ...
著者Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M.
登録日2019-03-28
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
6R79
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BU of 6r79 by Molmil
Structure of IMP-13 metallo-beta-lactamase in apo form (loop open)
分子名称: BETA-MERCAPTOETHANOL, Beta-lactamase, GLYCEROL, ...
著者Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M.
登録日2019-03-28
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
4QI2
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BU of 4qi2 by Molmil
X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA
分子名称: RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1
著者Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
登録日2014-05-30
公開日2014-07-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-16
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
1ZZP
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BU of 1zzp by Molmil
Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
分子名称: Proto-oncogene tyrosine-protein kinase ABL1
著者Hantschel, O, Wiesner, S, Guttler, T, Mackereth, C.D, Rix, L.L.R, Mikes, Z, Dehne, J, Gorlich, D, Sattler, M, Superti-Furga, G.
登録日2005-06-14
公開日2005-08-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19, 2005
1MAZ
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BU of 1maz by Molmil
X-RAY STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH
分子名称: Bcl-2-like protein 1
著者Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W.
登録日1996-04-09
公開日1997-04-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
6STF
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BU of 6stf by Molmil
Human Rab8a phosphorylated at Ser111 in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-8A
著者Vieweg, S, Mulholland, K, Braeuning, B, Kachariya, N, Lai, Y, Toth, R, Sattler, M, Groll, M, Itzen, A, Muqit, M.M.K.
登録日2019-09-10
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
Biochem.J., 477, 2020
6STG
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BU of 6stg by Molmil
Human Rab8a phosphorylated at Ser111 in complex with GPPNP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Vieweg, S, Mulholland, K, Braeuning, B, Kachariya, N, Lai, Y, Toth, R, Sattler, M, Groll, M, Itzen, A, Muqit, M.M.K.
登録日2019-09-10
公開日2020-04-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
Biochem.J., 477, 2020
4QI0
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BU of 4qi0 by Molmil
X-ray structure of the ROQ domain from murine Roquin-1
分子名称: 1,2-ETHANEDIOL, Roquin-1
著者Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
登録日2014-05-30
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
6I41
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BU of 6i41 by Molmil
Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-08
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I5P
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BU of 6i5p by Molmil
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
分子名称: Bromodomain-containing protein 3, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2018-11-14
公開日2019-05-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6RZS
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BU of 6rzs by Molmil
Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed ertapenem
分子名称: Beta-lactamase, ZINC ION, hydrolysed ertapenem
著者Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M.
登録日2019-06-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
6S0H
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BU of 6s0h by Molmil
Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed doripenem
分子名称: (2~{R},3~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-3-methyl-4-[(3~{S},5~{S})-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-2,3-dihydro-1~{H}-pyrrole-5-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ...
著者Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M.
登録日2019-06-14
公開日2020-04-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
6RT2
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BU of 6rt2 by Molmil
Crystal structure of Trypanosoma Brucei PEX14 N-terminal domain in complex with small molecules designed to investigate the water envelope
分子名称: (3~{S})-3-[[1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-3-yl]carbonylamino]-3-phenyl-propanoic acid, BETA-MERCAPTOETHANOL, Peroxin 14, ...
著者Napolitano, V, Ratkova, E.L, Dawidowski, M, Dubin, G, Fino, R, Popowicz, G, Sattler, M, Tetko, I.V.
登録日2019-05-22
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Water envelope has a critical impact on the design of protein-protein interaction inhibitors.
Chem.Commun.(Camb.), 56, 2020
6RZR
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BU of 6rzr by Molmil
Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed imipenem
分子名称: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase, ...
著者Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M.
登録日2019-06-13
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase.
Antimicrob.Agents Chemother., 64, 2020
1LXL
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BU of 1lxl by Molmil
NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
分子名称: BCL-XL
著者Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W.
登録日1996-04-04
公開日1997-04-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
1O0P
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BU of 1o0p by Molmil
Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
分子名称: Splicing Factor SF1, Splicing factor U2AF 65 kDa subunit
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-02-24
公開日2003-05-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
1OQJ
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BU of 1oqj by Molmil
Crystal structure of the SAND domain from glucocorticoid modulatory element binding protein-1 (GMEB1)
分子名称: Glucocorticoid Modulatory Element Binding protein-1, ZINC ION
著者Surdo, P.L, Bottomley, M.J, Sattler, M, Scheffzek, K.
登録日2003-03-10
公開日2003-11-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions
MOL.ENDOCRINOL., 17, 2003
1OPI
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BU of 1opi by Molmil
SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE
分子名称: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-03-05
公開日2004-03-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
2MKL
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BU of 2mkl by Molmil
Solution structure of the fourth constant immunoglobulin domain of nurse shark IgNAR
分子名称: Novel antigen receptor
著者Hennig, J, Sattler, M.
登録日2014-02-10
公開日2014-07-02
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
6ELD
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BU of 6eld by Molmil
Crystal structure of TIA-1 RRM1 in complex with U1C
分子名称: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C
著者Jagtap, P.K.A, Sattler, M.
登録日2017-09-28
公開日2018-10-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Crystal structure of TIA-1 RRM1 in complex with U1C
To Be Published
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
6F8F
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BU of 6f8f by Molmil
Co-crystal structure of SPOP MATH domain and human Pdx1 fragment
分子名称: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
著者Ostertag, M.S, Popowicz, G.M, Sattler, M.
登録日2017-12-13
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
2L1L
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BU of 2l1l by Molmil
NMR Solution Structure of the Phi0 PKI NES Peptide in Complex with CRM1-RanGTP
分子名称: Exportin-1, cAMP-dependent protein kinase inhibitor alpha
著者Madl, T, Sattler, M.
登録日2010-07-29
公開日2011-06-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
4B9W
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BU of 4b9w by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45.
分子名称: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1
著者Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
登録日2012-09-08
公開日2012-10-17
最終更新日2019-04-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012

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