1ZZP
Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
Summary for 1ZZP
Entry DOI | 10.2210/pdb1zzp/pdb |
NMR Information | BMRB: 6570 |
Descriptor | Proto-oncogene tyrosine-protein kinase ABL1 (1 entity in total) |
Functional Keywords | four helix bundle, nuclear export signal, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 1 |
Total formula weight | 14150.12 |
Authors | Hantschel, O.,Wiesner, S.,Guttler, T.,Mackereth, C.D.,Rix, L.L.R.,Mikes, Z.,Dehne, J.,Gorlich, D.,Sattler, M.,Superti-Furga, G. (deposition date: 2005-06-14, release date: 2005-08-30, Last modification date: 2024-05-22) |
Primary citation | Hantschel, O.,Wiesner, S.,Guttler, T.,Mackereth, C.D.,Rix, L.L.R.,Mikes, Z.,Dehne, J.,Gorlich, D.,Sattler, M.,Superti-Furga, G. Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl. Mol.Cell, 19:461-473, 2005 Cited by PubMed: 16109371DOI: 10.1016/j.molcel.2005.06.030 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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