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PDB: 149 件

1BXL
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STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: BAK PEPTIDE, BCL-XL
著者Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W.
登録日1996-10-16
公開日1997-10-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
2MJN
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BU of 2mjn by Molmil
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1
分子名称: Nucleolysin TIA-1 isoform p40
著者Sattler, M, Wang, I.
登録日2014-01-13
公開日2014-04-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
Nucleic Acids Res., 42, 2014
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
著者Kachariya, N, Sattler, M, Keil, P, Strasser, K.
登録日2022-10-04
公開日2022-11-09
最終更新日2024-06-19
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
6DCL
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Crystal structure of UP1 bound to pri-miRNA-18a terminal loop
分子名称: 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3')
著者Kooshapur, H, Sattler, M.
登録日2018-05-07
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
4EL6
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BU of 4el6 by Molmil
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
分子名称: IL-4-inducing protein
著者Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J.
登録日2012-04-10
公開日2013-04-10
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
分子名称: Splicing factor U2AF 65 kDa subunit
著者Kang, H.-S, Sattler, M.
登録日2019-12-17
公開日2020-05-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
8POI
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Molecular Docking of SPF30 Tudor domain with synthetic inhibitor 4-(pyridin-2-yl)thiazol-2-amine
分子名称: 4-pyridin-2-yl-1,3-thiazol-2-amine, Survival of motor neuron-related-splicing factor 30
著者Borggraefe, J, Gaussmann, S, Sattler, M.
登録日2023-07-04
公開日2023-08-23
最終更新日2023-08-30
実験手法SOLUTION NMR
主引用文献Pharmacological perturbation of the phase-separating protein SMNDC1.
Nat Commun, 14, 2023
1FHO
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BU of 1fho by Molmil
Solution Structure of the PH Domain from the C. Elegans Muscle Protein UNC-89
分子名称: UNC-89
著者Blomberg, N, Baraldi, E, Sattler, M, Saraste, M, Nilges, M.
登録日2000-08-02
公開日2000-10-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function.
Structure Fold.Des., 8, 2000
3DXB
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BU of 3dxb by Molmil
Structure of the UHM domain of Puf60 fused to thioredoxin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM)
著者Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M.
登録日2008-07-24
公開日2008-10-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
8P25
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Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
分子名称: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
著者Hipp, C, Sattler, M.
登録日2023-05-14
公開日2023-07-26
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
8PXX
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Structure of the WW domain tandem of PRPF40A in complex with SF1
分子名称: Pre-mRNA-processing factor 40 homolog A, Splicing factor 1
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
8PXW
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Structure of the WW domain tandem of PRPF40A
分子名称: Pre-mRNA-processing factor 40 homolog A
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
2JW6
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Solution structure of the DEAF1 MYND domain
分子名称: Deformed epidermal autoregulatory factor 1 homolog, ZINC ION
著者Spadaccini, R, Perrin, H, Bottomley, M, Ansieu, S, Sattler, M.
登録日2007-10-08
公開日2007-12-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Retraction notice to "Structure and functional analysis of the MYND domain" [J. Mol. Biol. (2006) 358, 498-508].
J.Mol.Biol., 376, 2008
1D8B
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BU of 1d8b by Molmil
NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE
分子名称: SGS1 RECQ HELICASE
著者Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M.
登録日1999-10-21
公開日2000-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
5L87
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BU of 5l87 by Molmil
Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases.
分子名称: 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14
著者Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M.
登録日2016-06-07
公開日2017-03-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.87 Å)
主引用文献Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
2JXC
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BU of 2jxc by Molmil
Structure of the EPS15-EH2 Stonin2 Complex
分子名称: CALCIUM ION, Epidermal growth factor receptor substrate 15, Stonin-2
著者Rumpf, J, Simon, B, Jung, N, Maritzen, T, Haucke, V, Sattler, M, Groemping, Y.
登録日2007-11-12
公開日2008-01-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
Embo J., 27, 2008
5AGQ
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BU of 5agq by Molmil
Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes
分子名称: BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A
著者Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M.
登録日2015-02-03
公開日2015-05-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
6Y91
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Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with NADH
分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M.
登録日2020-03-06
公開日2021-03-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity.
Commun Biol, 4, 2021
1T2R
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BU of 1t2r by Molmil
Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
1T2S
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Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain
分子名称: 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2
著者Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
登録日2004-04-22
公開日2004-06-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
7Z0J
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human PEX13 SH3 domain in complex with internal FxxxF motif
分子名称: 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13
著者Gaussmann, S, Zak, K, Kreisz, N, Sattler, M.
登録日2022-02-23
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
7Z0K
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human PEX13 SH3 in complex with PEX5 W4 (WxxxF/Y) motif
分子名称: Peroxisomal membrane protein PEX13,Peroxisomal targeting signal 1 receptor
著者Gaussmann, S, Napolitano, V, sattler, M.
登録日2022-02-23
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
7Z0I
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human PEX13 SH3 domain
分子名称: 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13, ZINC ION
著者Gaussmann, S, Zak, K, Sattler, M.
登録日2022-02-23
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
1SHC
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SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: SHC, TRKA RECEPTOR PHOSPHOPEPTIDE
著者Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W.
登録日1996-03-27
公開日1997-05-15
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
7AAF
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Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
分子名称: U2 snRNP auxiliary factor large subunit
著者Kawale, A.A, Kang, H.S, Sattler, M.
登録日2020-09-04
公開日2021-10-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published

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