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PDB: 889 results
4OJ9
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BU of 4oj9 by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, GLYCEROL, HYDROXYFLUTAMIDE, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-20
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OGH
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BU of 4ogh by Molmil
Crystal structure of T877A-AR-LBD
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, SULFATE ION
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-16
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OEY
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BU of 4oey by Molmil
Crystal structure of AR-LBD bound with co-regulator peptide
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, SULFATE ION, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-14
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OH6
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BU of 4oh6 by Molmil
Crystal structure of T877A-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, HYDROXYFLUTAMIDE, Protein BUD31 homolog, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-17
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
4OKB
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BU of 4okb by Molmil
Crystal structure of W741L-AR-LBD bound with co-regulator peptide
Descriptor: Androgen receptor, Protein BUD31 homolog, R-BICALUTAMIDE, ...
Authors:Liu, J.S, Hsu, C.L, Wu, W.G.
Deposit date:2014-01-22
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.
Mol Oncol, 8, 2014
5L0O
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BU of 5l0o by Molmil
IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
Descriptor: Ras GTPase-activating-like protein IQGAP1
Authors:Liu, J, Worthylake, D.
Deposit date:2016-07-27
Release date:2016-09-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
3ZPB
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BU of 3zpb by Molmil
INFLUENZA VIRUS (VN1194) H5 E190D mutant HA with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-27
Release date:2013-10-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZP0
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BU of 3zp0 by Molmil
INFLUENZA VIRUS (VN1194) H5 HA with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZPA
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BU of 3zpa by Molmil
INFLUENZA VIRUS (VN1194) H5 I155F mutant HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ
Authors:Liu, J, Chen, Z, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-27
Release date:2013-10-02
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZP3
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BU of 3zp3 by Molmil
INFLUENZA VIRUS (VN1194) H5 HA A138V mutant with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid, ...
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZP1
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BU of 3zp1 by Molmil
INFLUENZA VIRUS (VN1194) H5 HA with LSTc
Descriptor: HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-2)-beta-D-galactopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZP2
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BU of 3zp2 by Molmil
INFLUENZA VIRUS (VN1194) H5 HA A138V mutant with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
3ZP6
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BU of 3zp6 by Molmil
INFLUENZA VIRUS (VN1194) H5 E190D mutant HA with LSTc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose
Authors:Liu, J, Stevens, D.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2013-02-26
Release date:2013-10-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Changes in the Hemagglutinin of H5N1 Viruses During Human Infection - Influence on Receptor Binding.
Virology, 447, 2013
6WW4
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BU of 6ww4 by Molmil
Crystal structure of HERC2 ZZ domain in complex with histone H3 tail
Descriptor: GLYCEROL, Histone H3.1,E3 ubiquitin-protein ligase HERC2, ZINC ION
Authors:Liu, J, Vann, K.R, Kutateladze, T.G.
Deposit date:2020-05-07
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure, 28, 2020
6WW3
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BU of 6ww3 by Molmil
Crystal structure of HERC2 ZZ domain in complex with SUMO1 tail
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, SUMO1 linked HERC2 ZZ domain (Small ubiquitin-related modifier 1,E3 ubiquitin-protein ligase HERC2), ...
Authors:Liu, J, Vann, K.R, Kutateladze, T.G.
Deposit date:2020-05-07
Release date:2020-08-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Structure, 28, 2020
8HOG
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BU of 8hog by Molmil
Crystal structure of Bcl-2 in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOH
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BU of 8hoh by Molmil
Crystal structure of Bcl-2 G101V in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOI
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BU of 8hoi by Molmil
Crystal structure of Bcl-2 D103Y in complex with sonrotoclax
Descriptor: Apoptosis regulator Bcl-2, FORMIC ACID, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Authors:Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
Deposit date:2022-12-10
Release date:2024-01-17
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HTR
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BU of 8htr by Molmil
Crystal structure of Bcl2 in complex with S-9c
Descriptor: 4-[4-[(2~{S})-2-(2-chlorophenyl)pyrrolidin-1-yl]phenyl]-~{N}-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide, Apoptosis regulator Bcl-2
Authors:Liu, J, Xu, M, Feng, Y, Liu, Y.
Deposit date:2022-12-21
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2.
J.Med.Chem., 67, 2024
8HTS
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BU of 8hts by Molmil
Crystal structure of Bcl2 in complex with S-10r
Descriptor: 4-[2-[(2~{S})-2-(2-cyclopropylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-~{N}-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide, Apoptosis regulator Bcl-2
Authors:Liu, J, Xu, M, Feng, Y, Liu, Y.
Deposit date:2022-12-21
Release date:2024-05-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl-2.
J.Med.Chem., 67, 2024
1SJJ
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BU of 1sjj by Molmil
Cryo-EM Structure of Chicken Gizzard Smooth Muscle alpha-Actinin
Descriptor: actinin
Authors:Liu, J, Taylor, D.W, Taylor, K.A.
Deposit date:2004-03-03
Release date:2004-03-23
Last modified:2024-02-14
Method:ELECTRON CRYSTALLOGRAPHY (20 Å)
Cite:A 3-D Reconstruction of Smooth Muscle alpha-Actinin by CryoEm Reveals Two Different Conformations at the Actin-binding Region.
J.Mol.Biol., 338, 2004
6V9C
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BU of 6v9c by Molmil
Crystal structure of FGFR4 kinase domain in complex with covalent inhibitor
Descriptor: Fibroblast growth factor receptor 4, N-[(3R,4S)-4-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)-8-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino}oxolan-3-yl]prop-2-enamide, SULFATE ION
Authors:Liu, J, Liu, H.
Deposit date:2019-12-13
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma.
Acs Med.Chem.Lett., 11, 2020
8GW3
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BU of 8gw3 by Molmil
Crystal structure of human TAK1 kinase domain fused with TAB1
Descriptor: Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Authors:Liu, J, Sun, W, Gao, J.
Deposit date:2022-09-16
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of human TAK1 kinase domain fused with TAB1
To Be Published
6IR8
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BU of 6ir8 by Molmil
Rice WRKY/DNA complex
Descriptor: DNA (5'-D(P*GP*AP*TP*AP*TP*TP*TP*GP*AP*CP*CP*GP*GP*A)-3'), DNA (5'-D(P*TP*CP*CP*GP*GP*TP*CP*AP*AP*AP*TP*AP*TP*C)-3'), OsWRKY45, ...
Authors:Liu, J, Cheng, X, Wang, D.
Deposit date:2018-11-12
Release date:2019-02-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain.
Nucleic Acids Res., 47, 2019
4X3Q
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BU of 4x3q by Molmil
Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, SibL
Authors:liu, J.S, Chen, S.C, Yang, C.S, Huang, C.H, Chen, Y.
Deposit date:2014-12-01
Release date:2015-11-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with SAH
To Be Published, 2015

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PDB entries from 2024-11-13

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