1ZI6
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![BU of 1zi6 by Molmil](/molmil-images/mine/1zi6) | Crystal Structure Analysis of the dienelactone hydrolase (C123S) mutant- 1.7 A | 分子名称: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | 著者 | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | 登録日 | 2005-04-27 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase. Acta Crystallogr.,Sect.D, 61, 2005
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1T0P
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![BU of 1t0p by Molmil](/molmil-images/mine/1t0p) | Structural Basis of ICAM recognition by integrin alpahLbeta2 revealed in the complex structure of binding domains of ICAM-3 and alphaLbeta2 at 1.65 A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, Intercellular adhesion molecule-3, ... | 著者 | Song, G, Yang, Y.T, Liu, J.H, Shimaoko, M, Springer, T.A, Wang, J.H. | 登録日 | 2004-04-12 | 公開日 | 2005-03-08 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2. Proc.Natl.Acad.Sci.Usa, 102, 2005
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2A5A
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![BU of 2a5a by Molmil](/molmil-images/mine/2a5a) | Crystal structure of unbound SARS coronavirus main peptidase in the space group C2 | 分子名称: | 1,2-ETHANEDIOL, 3C-like peptidase, CHLORIDE ION | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N. | 登録日 | 2005-06-30 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide J.Mol.Biol., 353, 2005
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2NOC
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![BU of 2noc by Molmil](/molmil-images/mine/2noc) | Solution Structure of Putative periplasmic protein: Northest Structural Genomics Target StR106 | 分子名称: | Putative periplasmic protein | 著者 | Zhang, Q, Liu, G, Wang, H, Nwosu, C, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-10-25 | 公開日 | 2006-11-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Putative periplasmic protein: Northest Structural Genomics Target StR106 To be Published
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5H6B
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![BU of 5h6b by Molmil](/molmil-images/mine/5h6b) | Crystal structure of a thermostable lipase from Marine Streptomyces | 分子名称: | ACETATE ION, IMIDAZOLE, Putative secreted lipase, ... | 著者 | Hou, S, Zhao, Z, Liu, J. | 登録日 | 2016-11-11 | 公開日 | 2017-09-20 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity FEBS J., 284, 2017
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5H6G
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![BU of 5h6g by Molmil](/molmil-images/mine/5h6g) | Crystal structure of a thermostable lipase from Marine Streptomyces | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | 著者 | Hou, S, Zhao, Z, Liu, J. | 登録日 | 2016-11-11 | 公開日 | 2017-09-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Crystal structure of a lipase from Streptomyces sp. strain W007 - implications for thermostability and regiospecificity FEBS J., 284, 2017
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2D2H
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![BU of 2d2h by Molmil](/molmil-images/mine/2d2h) | OpdA from Agrobacterium radiobacter with bound inhibitor trimethyl phosphate at 1.8 A resolution | 分子名称: | COBALT (II) ION, TRIMETHYL PHOSPHATE, phosphotriesterase | 著者 | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | 登録日 | 2005-09-09 | 公開日 | 2005-09-20 | 最終更新日 | 2015-08-19 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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1R29
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![BU of 1r29 by Molmil](/molmil-images/mine/1r29) | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB Domain to 1.3 Angstrom | 分子名称: | B-cell lymphoma 6 protein | 著者 | Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G. | 登録日 | 2003-09-26 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol.Cell, 12, 2003
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8HB9
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![BU of 8hb9 by Molmil](/molmil-images/mine/8hb9) | Crystal Structure of Human IDH1 R132H Mutant in Complex with NADPH and Compound IHMT-IDH1-053 | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | 著者 | Guo, G, Wang, B, Liu, J, Liu, Q. | 登録日 | 2022-10-27 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based discovery of IHMT-IDH1-053 as a potent irreversible IDH1 mutant selective inhibitor. Eur.J.Med.Chem., 256, 2023
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5T0A
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![BU of 5t0a by Molmil](/molmil-images/mine/5t0a) | Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, Krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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5T05
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![BU of 5t05 by Molmil](/molmil-images/mine/5t05) | Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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2V5S
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![BU of 2v5s by Molmil](/molmil-images/mine/2v5s) | Structural basis for Dscam isoform specificity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM | 著者 | Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H. | 登録日 | 2007-07-09 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of Dscam Isoform Specificity Nature, 449, 2007
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2V5M
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![BU of 2v5m by Molmil](/molmil-images/mine/2v5m) | Structural basis for Dscam isoform specificity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DSCAM, GLYCEROL | 著者 | Meijers, R, Puettmann-Holgado, R, Skiniotis, G, Liu, J.-H, Walz, T, Schmucker, D, Wang, J.-H. | 登録日 | 2007-07-06 | 公開日 | 2007-09-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Basis of Dscam Isoform Specificity Nature, 449, 2007
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2D2J
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![BU of 2d2j by Molmil](/molmil-images/mine/2d2j) | OpdA from Agrobacterium radiobacter without inhibitor/product present at 1.75 A resolution | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, phosphotriesterase | 著者 | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | 登録日 | 2005-09-09 | 公開日 | 2005-09-20 | 最終更新日 | 2015-08-19 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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2D2G
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![BU of 2d2g by Molmil](/molmil-images/mine/2d2g) | OpdA from Agrobacterium radiobacter with bound product dimethylthiophosphate | 分子名称: | COBALT (II) ION, O,O-DIMETHYL HYDROGEN THIOPHOSPHATE, phosphotriesterase | 著者 | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | 登録日 | 2005-09-08 | 公開日 | 2005-09-20 | 最終更新日 | 2015-08-19 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochim.Biophys.Acta, 1752, 2005
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3AZT
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![BU of 3azt by Molmil](/molmil-images/mine/3azt) | Diverse Substrates Recognition Mechanism Revealed by Thermotoga maritima Cel5A Structures in Complex with Cellotetraose | 分子名称: | Endoglucanase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Chen, C.C, Cheng, Y.S, Liu, J.R, Guo, R.T. | 登録日 | 2011-05-30 | 公開日 | 2011-08-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta, 1814, 2011
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1R2B
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![BU of 1r2b by Molmil](/molmil-images/mine/1r2b) | Crystal structure of the BCL6 BTB domain complexed with a SMRT co-repressor peptide | 分子名称: | B-cell lymphoma 6 protein, Nuclear receptor co-repressor 2 | 著者 | Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G. | 登録日 | 2003-09-26 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol.Cell, 12, 2003
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1R28
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![BU of 1r28 by Molmil](/molmil-images/mine/1r28) | Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom | 分子名称: | B-cell lymphoma 6 protein | 著者 | Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G. | 登録日 | 2003-09-26 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol.Cell, 12, 2003
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1RPY
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![BU of 1rpy by Molmil](/molmil-images/mine/1rpy) | CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS | 分子名称: | SULFATE ION, adaptor protein APS | 著者 | Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R. | 登録日 | 2003-12-03 | 公開日 | 2003-12-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol.Cell, 12, 2003
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5T03
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![BU of 5t03 by Molmil](/molmil-images/mine/5t03) | Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate | 分子名称: | 1,2-ETHANEDIOL, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ADENOSINE-3'-5'-DIPHOSPHATE, ... | 著者 | Pedersen, L.C, Moon, A.F, Krahn, J.M, Liu, J. | 登録日 | 2016-08-15 | 公開日 | 2017-02-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases. ACS Chem. Biol., 12, 2017
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8B37
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![BU of 8b37 by Molmil](/molmil-images/mine/8b37) | Crystal structure of Pyrobaculum aerophilum potassium-independent proton pumping membrane integral pyrophosphatase in complex with imidodiphosphate and magnesium, and with bound sulphate | 分子名称: | IMIDODIPHOSPHORIC ACID, K(+)-insensitive pyrophosphate-energized proton pump, MAGNESIUM ION, ... | 著者 | Strauss, J, Wilkinson, C, Vidilaseris, K, Ribeiro, O, Liu, J, Hillier, J, Malinen, A, Gehl, B, Jeuken, L.C, Pearson, A.R, Goldman, A. | 登録日 | 2022-09-16 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.84 Å) | 主引用文献 | Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases. Embo Rep., 25, 2024
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1TU4
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![BU of 1tu4 by Molmil](/molmil-images/mine/1tu4) | Crystal Structure of Rab5-GDP Complex | 分子名称: | COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-5A, ... | 著者 | Zhu, G, Zhai, P, Liu, J, Terzyan, S, Li, G, Zhang, X.C. | 登録日 | 2004-06-24 | 公開日 | 2004-10-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of Rab5-Rabaptin5 interaction in endocytosis Nat.Struct.Mol.Biol., 11, 2004
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2B22
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![BU of 2b22 by Molmil](/molmil-images/mine/2b22) | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat | 分子名称: | General control protein GCN4, SODIUM ION | 著者 | Deng, Y, Liu, J, Zheng, Q, Eliezer, D, Kallenbach, N.R, Lu, M. | 登録日 | 2005-09-16 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure, 14, 2006
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2B1F
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![BU of 2b1f by Molmil](/molmil-images/mine/2b1f) | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat | 分子名称: | General control protein GCN4 | 著者 | Deng, Y, Liu, J, Zheng, Q, Eliezer, D, Kallenbach, N.R, Lu, M. | 登録日 | 2005-09-15 | 公開日 | 2006-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat. Structure, 14, 2006
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1XS2
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![BU of 1xs2 by Molmil](/molmil-images/mine/1xs2) | Structural Basis for Catalytic Racemization and Substrate Specificity of an N-Acylamino Acid Racemase Homologue from Deinococcus radiodurans | 分子名称: | MAGNESIUM ION, N-Acylamino Acid Racemase | 著者 | Wang, W.-C, Chiu, W.-C, Hsu, S.-K, Wu, C.-L, Chen, C.-Y, Liu, J.-S, Hsu, W.-H. | 登録日 | 2004-10-18 | 公開日 | 2004-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for catalytic racemization and substrate specificity of an N-acylamino acid racemase homologue from Deinococcus radiodurans J.Mol.Biol., 342, 2004
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