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PDB: 629 results

5WNH
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BU of 5wnh by Molmil
X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR
Descriptor: (2R)-N-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide, Rho-associated protein kinase 1
Authors:Li, X.
Deposit date:2017-07-31
Release date:2018-08-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published
7VBQ
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BU of 7vbq by Molmil
Heterodimer structure of Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxIJ
Descriptor: FE (III) ION, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxI, Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxJ, ...
Authors:Li, X, Awakawa, T, Mori, T, Abe, I.
Deposit date:2021-09-01
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis.
J.Am.Chem.Soc., 143, 2021
7VBR
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BU of 7vbr by Molmil
Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxI
Descriptor: Fe(II)/(alpha)ketoglutarate-dependent dioxygenase TlxI
Authors:Li, X, Awakawa, T, Mori, T, Abe, I.
Deposit date:2021-09-01
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis.
J.Am.Chem.Soc., 143, 2021
9F3E
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BU of 9f3e by Molmil
Single acyclic phosphonate nucleotide (R)-ZNA modification on DNA duplex
Descriptor: C modified (R)-ZNA
Authors:Li, X, Groaz, E, Herdewyn, P, Lescrinier, E.
Deposit date:2024-04-25
Release date:2024-06-05
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability.
Chemistry, 30, 2024
8IBI
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BU of 8ibi by Molmil
Inactive mutant of CtPL-H210S/F214I
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Li, X, Shi, B.L, Zeng, Z.Y, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-10
Release date:2023-04-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Functional tailoring of a PET hydrolytic enzyme expressed in Pichia pastoris.
Bioresour Bioprocess, 10, 2023
8IBJ
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BU of 8ibj by Molmil
Inactive mutant of CtPL-H210S/F214I/N181A/F235L
Descriptor: PET hydrolase
Authors:Li, X, Shi, B.L, Zeng, Z.Y, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-10
Release date:2023-04-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Functional tailoring of a PET hydrolytic enzyme expressed in Pichia pastoris.
Bioresour Bioprocess, 10, 2023
8IAN
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BU of 8ian by Molmil
Crystal structure of CtPL-H210S/F214I mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PET hydrolase
Authors:Li, X, Shi, B.L, Zeng, Z.Y, Huang, J.-W, Chen, C.-C, Guo, R.-T.
Deposit date:2023-02-08
Release date:2023-04-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Functional tailoring of a PET hydrolytic enzyme expressed in Pichia pastoris.
Bioresour Bioprocess, 10, 2023
7Y9I
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BU of 7y9i by Molmil
Complex structure of AtYchF1 with ppGpp
Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2022-06-24
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Co-crystalization reveals the interaction between AtYchF1 and ppGpp.
Front Mol Biosci, 9, 2022
7YMN
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BU of 7ymn by Molmil
Cryo-EM structure of in vitro PHF fibril
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Li, X, Liu, C.
Deposit date:2022-07-28
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Subtle change of fibrillation condition leads to substantial alteration of recombinant Tau fibril structure.
Iscience, 25, 2022
6N7X
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BU of 6n7x by Molmil
S. cerevisiae U1 snRNP
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ...
Authors:Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R.
Deposit date:2018-11-28
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing.
Nat Commun, 8, 2017
7CR2
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BU of 7cr2 by Molmil
human KCNQ2 in complex with retigabine
Descriptor: Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
7CR7
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BU of 7cr7 by Molmil
human KCNQ2-CaM in complex with retigabine
Descriptor: Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2, ethyl N-[2-azanyl-4-[(4-fluorophenyl)methylamino]phenyl]carbamate
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
7CR0
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BU of 7cr0 by Molmil
human KCNQ2 in apo state
Descriptor: Potassium voltage-gated channel subfamily KQT member 2
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
7CR3
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BU of 7cr3 by Molmil
human KCNQ2-CaM in apo state
Descriptor: Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 2
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
7CR4
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BU of 7cr4 by Molmil
human KCNQ2-CaM in complex with ztz240
Descriptor: Calmodulin-3, N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
7XIN
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BU of 7xin by Molmil
Crystal structure of DODC from Pseudomonas
Descriptor: DOPA decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Li, X, Zhou, Y.L, Liao, L.J, Liu, X.K, Liu, B, Guo, Y, Feng, Z, Sun, D.Y, Zeng, Z.X.
Deposit date:2022-04-13
Release date:2023-04-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of DODC from Pseudomonas
To Be Published
7WJG
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BU of 7wjg by Molmil
Streptococcus mutans BusR transcriptional factor
Descriptor: CITRIC ACID, Putative transcriptional regulator (GntR family)
Authors:Li, X, Liu, N.
Deposit date:2022-01-06
Release date:2023-01-11
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural study of transcriptional factor BusR
To Be Published
7CR1
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BU of 7cr1 by Molmil
human KCNQ2 in complex with ztz240
Descriptor: N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2
Authors:Li, X, Lv, D, Wang, J, Ye, S, Guo, J.
Deposit date:2020-08-12
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for ligand activation of the human KCNQ2 channel.
Cell Res., 31, 2021
8JQE
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BU of 8jqe by Molmil
Structure of CmCBDA in complex with Mn2+ and glycerol
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Li, X.
Deposit date:2023-06-14
Release date:2024-01-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural Insights into the Catalytic Activity of Cyclobacterium marinum N -Acetylglucosamine Deacetylase.
J.Agric.Food Chem., 72, 2024
8JQF
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BU of 8jqf by Molmil
Structure of CmCBDA in complex with Ni2+ and Glycerol
Descriptor: GLYCEROL, NICKEL (II) ION, SULFATE ION, ...
Authors:Li, X.
Deposit date:2023-06-14
Release date:2024-01-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into the Catalytic Activity of Cyclobacterium marinum N -Acetylglucosamine Deacetylase.
J.Agric.Food Chem., 72, 2024
7VS7
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BU of 7vs7 by Molmil
Crystal structure of the ectodomain of OsCERK1 in complex with chitin hexamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitin elicitor receptor kinase 1, ...
Authors:Li, X.
Deposit date:2021-10-26
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.015 Å)
Cite:Structural insight into chitin perception by chitin elicitor receptor kinase 1 of Oryza sativa.
J Integr Plant Biol, 65, 2023
3ZIF
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BU of 3zif by Molmil
Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
Descriptor: HEXON PROTEIN, PENTON PROTEIN, PIX, ...
Authors:Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P.
Deposit date:2013-01-09
Release date:2014-01-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
5VBL
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BU of 5vbl by Molmil
Structure of apelin receptor in complex with agonist peptide
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apelin receptor,Rubredoxin,Apelin receptor Chimera, ZINC ION, ...
Authors:Ma, Y, Yue, Y, Ma, Y, Zhang, Q, Zhou, Q, Song, Y, Shen, Y, Li, X, Ma, X, Li, C, Hanson, M.A, Han, G.W, Sickmier, E.A, Swaminath, G, Zhao, S, Stevems, R.C, Hu, L.A, Zhong, W, Zhang, M, Xu, F.
Deposit date:2017-03-29
Release date:2017-05-31
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Apelin Control of the Human Apelin Receptor
Structure, 25, 2017
6WEJ
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BU of 6wej by Molmil
Structure of cGMP-unbound WT TAX-4 reconstituted in lipid nanodiscs
Descriptor: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel, ...
Authors:Zheng, X, Fu, Z, Su, D, Zhang, Y, Li, M, Pan, Y, Li, H, Li, S, Grassucci, R.A, Ren, Z, Hu, Z, Li, X, Zhou, M, Li, G, Frank, J, Yang, J.
Deposit date:2020-04-02
Release date:2020-06-03
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ligand activation of a eukaryotic cyclic nucleotide-gated channel.
Nat.Struct.Mol.Biol., 27, 2020
2VVZ
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BU of 2vvz by Molmil
Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA
Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CHLORIDE ION, SIALIDASE A
Authors:Xu, G, Li, X, Andrew, P.W, Taylor, G.L.
Deposit date:2008-06-13
Release date:2008-06-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Catalytic Domain of Streptococcus Pneumoniae Sialidase Nana.
Acta Crystallogr.,Sect.F, 64, 2008

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