1ZTY
 
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1ZU0
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6OHU
 | | Structure of EBP and tamoxifen | | 分子名称: | (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE, 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | | 著者 | Long, T, Li, X. | | 登録日 | 2019-04-06 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.526 Å) | | 主引用文献 | Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.
Nat Commun, 10, 2019
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2OBS
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1Y4E
 | | NMR structure of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger | | 分子名称: | Sodium/hydrogen exchanger 1 | | 著者 | Slepkov, E.R, Rainey, J.K, Li, X, Liu, Y, Lindhout, D.A, Sykes, B.D, Fliegel, L. | | 登録日 | 2004-11-30 | | 公開日 | 2005-02-01 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
J.Biol.Chem., 280, 2005
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2OBT
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1XXE
 | | RDC refined solution structure of the AaLpxC/TU-514 complex | | 分子名称: | 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION | | 著者 | Coggins, B.E, McClerren, A.L, Jiang, L, Li, X, Rudolph, J, Hindsgaul, O, Raetz, C.R.H, Zhou, P. | | 登録日 | 2004-11-04 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined Solution Structure of the LpxC-TU-514 Complex and pK(a) Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design
Biochemistry, 44, 2005
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2FBS
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5ZZ3
 | | Crystal structure of intracellular B30.2 domain of BTN3A3 | | 分子名称: | Butyrophilin, subfamily 3, member A3 isoform b variant | | 著者 | Yang, Y.Y, Li, X, Liu, W.D, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2018-05-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
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4LA1
 | | Crystal structure of SjTGR (thioredoxin glutathione reductase from Schistosoma japonicumi)complex with FAD | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | | 著者 | Peng, Y, Wu, Q, Huang, F, Chen, J, Li, X, Zhou, X, Fan, X. | | 登録日 | 2013-06-18 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.348 Å) | | 主引用文献 | Crystal structure of SjTGR complex with FAD
To be Published
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4Q77
 | | Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus | | 分子名称: | GLYCEROL, HTH-type transcriptional regulator rot | | 著者 | Zhu, Y, Fan, X, Li, X, Teng, M. | | 登録日 | 2014-04-24 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structure of Rot, a global regulator of virulence genes in Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 70, 2014
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7SHN
 | | Cryo-EM structure of oleoyl-CoA-bound human peroxisomal fatty acid transporter ABCD1 | | 分子名称: | ATP-binding cassette sub-family D member 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | | 著者 | Wang, R, Li, X. | | 登録日 | 2021-10-09 | | 公開日 | 2021-11-03 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1.
Cell Res., 32, 2022
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7SHM
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7TBW
 | | The structure of ATP-bound ABCA1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Sun, Y, Li, X. | | 登録日 | 2021-12-22 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
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7TC0
 | | The structure of human ABCA1 in digitonin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | | 著者 | Sun, Y, Li, X. | | 登録日 | 2021-12-22 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
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7TBY
 | | The structure of human ABCA1 in nanodisc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | | 著者 | Sun, Y, Li, X. | | 登録日 | 2021-12-22 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
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7TBZ
 | | The structure of ABCA1 Y482C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ATP-binding cassette, ... | | 著者 | Sun, Y, Li, X. | | 登録日 | 2021-12-22 | | 公開日 | 2022-01-26 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cholesterol efflux mechanism revealed by structural analysis of human ABCA1 conformational states.
Nat Cardiovasc Res, 1, 2022
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7TUZ
 | | Cryo-EM structure of 7alpha,25-dihydroxycholesterol-bound EBI2/GPR183 in complex with Gi protein | | 分子名称: | (2S,4aS,4bS,7R,8S,8aS,9R,10aR)-7-[(2R,3R)-7-hydroxy-3,7-dimethyloctan-2-yl]-4a,7,8-trimethyltetradecahydrophenanthrene-2,9-diol, G-protein coupled receptor 183, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Chen, H, Hung, W, Li, X. | | 登録日 | 2022-02-03 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response.
Structure, 30, 2022
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7TUY
 | | Cryo-EM structure of GSK682753A-bound EBI2/GPR183 | | 分子名称: | 8-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-3-[(3,4-dichlorophenyl)methyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one, G-protein coupled receptor 183,Soluble cytochrome b562 fusion, anti-BRIL Fab Heavy chain, ... | | 著者 | Chen, H, Huang, W, Li, X. | | 登録日 | 2022-02-03 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response.
Structure, 30, 2022
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5J8J
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5LME
 | | Specific-DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase | | 分子名称: | ZINC ION, piggyBac transposase | | 著者 | Morellet, N, Taylor, J.A, Wieninger, S, Moriau, S, Li, X, Lescop, E, Mathy, N, Bischerour, J, Betermier, M, Bardiaux, B, Nilges, M, Craig, N.L, Hickman, A.B, Dyda, F, Guittet, E. | | 登録日 | 2016-07-30 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Sequence-specific DNA binding activity of the cross-brace zinc finger motif of the piggyBac transposase.
Nucleic Acids Res., 46, 2018
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7XY9
 | | Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | | 分子名称: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | | 著者 | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | | 登録日 | 2022-06-01 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | | 主引用文献 | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions.
Nat Commun, 14, 2023
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6IY3
 | | Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), Histone H2A, ... | | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
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6IY2
 | | Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), DNA (167-MER), ... | | 著者 | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | | 登録日 | 2018-12-12 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
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4F8E
 | | Crystal structure of human PRS1 D52H mutant | | 分子名称: | MAGNESIUM ION, Ribose-phosphate pyrophosphokinase 1, SULFATE ION | | 著者 | Chen, P, Teng, M, Li, X. | | 登録日 | 2012-05-17 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | A small disturbance, but a serious disease: the possible mechanism of D52H-mutant of human PRS1 that causes gout
Iubmb Life, 65, 2013
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