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4F8E

Crystal structure of human PRS1 D52H mutant

Summary for 4F8E
Entry DOI10.2210/pdb4f8e/pdb
DescriptorRibose-phosphate pyrophosphokinase 1, SULFATE ION, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsprpp synthesis, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight72571.86
Authors
Chen, P.,Teng, M.,Li, X. (deposition date: 2012-05-17, release date: 2013-05-22, Last modification date: 2024-03-20)
Primary citationChen, P.,Li, J.,Ma, J.,Teng, M.,Li, X.
A small disturbance, but a serious disease: the possible mechanism of D52H-mutant of human PRS1 that causes gout
Iubmb Life, 65:518-525, 2013
Cited by
PubMed: 23509005
DOI: 10.1002/iub.1154
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

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