5T6B
 
 | | X-ray structure of the KijD1 C3-methyltransfeerase, converted to monomeric form | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, S-ADENOSYL-L-HOMOCYSTEINE, Sugar 3-C-methyl transferase, ... | | Authors: | Holden, H.M, Thoden, J.B, Dow, G.T. | | Deposit date: | 2016-09-01 | | Release date: | 2016-09-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural studies on KijD1, a sugar C-3'-methyltransferase.
Protein Sci., 25, 2016
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3BXO
 | | Crystal Structure of Streptomyces venezuelae DesVI | | Descriptor: | 1,2-ETHANEDIOL, N,N-dimethyltransferase, PHENYL-URIDINE-5'-DIPHOSPHATE, ... | | Authors: | Holden, H.M, Burgie, E.S. | | Deposit date: | 2008-01-14 | | Release date: | 2008-03-25 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three-Dimensional Structure of DesVI from Streptomyces venezuelae: A Sugar N,N-Dimethyltransferase Required for dTDP-Desosamine Biosynthesis.
Biochemistry, 47, 2008
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1QOB
 | | FERREDOXIN MUTATION D62K | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN, SULFATE ION | | Authors: | Holden, H.M, Benning, M.M. | | Deposit date: | 1997-08-14 | | Release date: | 1998-01-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure-function relationships in Anabaena ferredoxin: correlations between X-ray crystal structures, reduction potentials, and rate constants of electron transfer to ferredoxin:NADP+ reductase for site-specific ferredoxin mutants.
Biochemistry, 36, 1997
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1QOG
 | | FERREDOXIN MUTATION S47A | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN, SULFATE ION | | Authors: | Holden, H.M, Benning, M.M. | | Deposit date: | 1997-08-14 | | Release date: | 1998-01-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure-function relationships in Anabaena ferredoxin: correlations between X-ray crystal structures, reduction potentials, and rate constants of electron transfer to ferredoxin:NADP+ reductase for site-specific ferredoxin mutants.
Biochemistry, 36, 1997
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1QOF
 | | FERREDOXIN MUTATION Q70K | | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN, SULFATE ION | | Authors: | Holden, H.M, Benning, M.M. | | Deposit date: | 1997-08-14 | | Release date: | 1998-01-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure-function relationships in Anabaena ferredoxin: correlations between X-ray crystal structures, reduction potentials, and rate constants of electron transfer to ferredoxin:NADP+ reductase for site-specific ferredoxin mutants.
Biochemistry, 36, 1997
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3GR9
 | | Crystal structure of ColD H188K S187N | | Descriptor: | 2-OXOGLUTARIC ACID, ColD | | Authors: | Holden, H.M, Cook, P.D, Kubiak, R.L, Toomey, D.P. | | Deposit date: | 2009-03-25 | | Release date: | 2009-06-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Two Site-Directed Mutations Are Required for the Conversion of a Sugar Dehydratase into an Aminotransferase.
Biochemistry, 48, 2009
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1Z24
 | | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution. | | Descriptor: | BILIVERDIN IX GAMMA CHROMOPHORE, Insecticyanin A form | | Authors: | Holden, H.M, Rypniewski, W.R, Law, J.H, Rayment, I. | | Deposit date: | 2005-03-07 | | Release date: | 2005-04-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The molecular structure of insecticyanin from the tobacco hornworm Manduca sexta L. at 2.6 A resolution.
Embo J., 6, 1987
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3TMN
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3NYU
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3NYT
 | | X-ray crystal structure of the WlbE (WpbE) aminotransferase from pseudomonas aeruginosa, mutation K185A, in complex with the PLP external aldimine adduct with UDP-3-amino-2-N-acetyl-glucuronic acid, at 1.3 angstrom resolution | | Descriptor: | (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name), Aminotransferase WbpE, SODIUM ION | | Authors: | Holden, H.M, Thoden, J.B. | | Deposit date: | 2010-07-15 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.301 Å) | | Cite: | Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase.
Protein Sci., 26, 2017
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3OA2
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4KCF
 | | X-ray Structure of a KijD3 in Complex with FMN and dTDP-3-amino-2,3,6-trideoxy-4-keto-3-methyl-D-glucose | | Descriptor: | FAD-dependent oxidoreductase, FLAVIN MONONUCLEOTIDE, [(2R,4S,6R)-4-azanyl-4,6-dimethyl-5,5-bis(oxidanyl)oxan-2-yl] [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate | | Authors: | Holden, H.M, Thoden, J.B, Branch, M.C, Zimmer, A.L, Bruender, N.A. | | Deposit date: | 2013-04-24 | | Release date: | 2013-05-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Active site architecture of a sugar N-oxygenase.
Biochemistry, 52, 2013
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3TEA
 | | Crystal structure of Arthrobacter sp. strain su 4-hydroxybenzoyl CoA thioesterase double mutant Q58E/E73A complexed with 4-hydroxyphenacyl CoA | | Descriptor: | 4-HYDROXYPHENACYL COENZYME A, 4-hydroxybenzoyl-CoA thioesterase | | Authors: | Holden, H.M, Thoden, J.B, Song, F, Zhuang, Z, Trujillo, M, Dunaway-Mariano, D. | | Deposit date: | 2011-08-12 | | Release date: | 2012-08-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU.
Biochemistry, 51, 2012
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2OGA
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2OGE
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2PA4
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4J7H
 | | Crystal structure of EvaA, a 2,3-dehydratase in complex with dTDP-benzene and dTDP-rhamnose | | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ... | | Authors: | Holden, H.M, Kubiak, R.L, Thoden, J.B. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-22 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
Biochemistry, 52, 2013
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3ETJ
 | | Crystal structure E. coli Purk in complex with Mg, ADP, and Pi | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, HYDROGENPHOSPHATE ION, ... | | Authors: | Holden, H.M, Thoden, J.B. | | Deposit date: | 2008-10-08 | | Release date: | 2008-10-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
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4J7G
 | | Crystal structure of EvaA, a 2,3-dehydratase in complex with dTDP-fucose and dTDP-rhamnose | | Descriptor: | 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, EvaA 2,3-dehydratase, [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate | | Authors: | Holden, H.M, Kubiak, R.L, Thoden, J.B. | | Deposit date: | 2013-02-13 | | Release date: | 2013-05-22 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.
Biochemistry, 52, 2013
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3DR4
 | | GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand | | Descriptor: | 1,2-ETHANEDIOL, Putative perosamine synthetase, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate | | Authors: | Holden, H.M, Cook, P.D, Carney, A.E. | | Deposit date: | 2008-07-10 | | Release date: | 2008-10-14 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
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3ETH
 | | Crystal structure of E. coli Purk in complex with MgATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit | | Authors: | Holden, H.M, Thoden, J.B. | | Deposit date: | 2008-10-08 | | Release date: | 2008-10-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli.
Biochemistry, 47, 2008
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3DR7
 | | GDP-perosamine synthase from Caulobacter crescentus with bound GDP-3-deoxyperosamine | | Descriptor: | (2R,3S,5S,6R)-5-amino-3-hydroxy-6-methyl-oxan-2-yl, 1,2-ETHANEDIOL, Putative perosamine synthetase | | Authors: | Holden, H.M, Cook, P.D, Carney, A.E. | | Deposit date: | 2008-07-10 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
Biochemistry, 47, 2008
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4TMN
 | | SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES | | Descriptor: | CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ... | | Authors: | Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W. | | Deposit date: | 1987-06-29 | | Release date: | 1989-01-09 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
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4HN0
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4HN1
 | | Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP | | Descriptor: | 1,2-ETHANEDIOL, Putative 3-epimerase in D-allose pathway, THYMIDINE, ... | | Authors: | Holden, H.M, Kubiak, R.L. | | Deposit date: | 2012-10-18 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
Biochemistry, 51, 2012
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