4HN1

Crystal Structure of H60N/Y130F double mutant of ChmJ, a 3'-monoepimerase from Streptomyces bikiniensis in complex with dTDP

Summary for 4HN1

• Entry DOI: 10.2210/pdb4hn1/pdb
• Related: 4HMZ 4HN0
• Descriptor: Putative 3-epimerase in D-allose pathway, 1,2-ETHANEDIOL, THYMIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: 3'-monoepimerase, natural product, deoxysugar, chalcomycin, dtdp-mycinose, cupin fold, nucleotide-linked sugar, epimerization, unknown function
• Biological source: Streptomyces bikiniensis
• Total number of polymer chains: 4
• Total formula weight: 92323.54

Authors

Holden, H.M.,Kubiak, R.L. (deposition date: 2012-10-18, release date: 2012-11-21, Last modification date: 2023-09-20)

• Primary citation: Kubiak, R.L.,Phillips, R.K.,Zmudka, M.W.,Ahn, M.R.,Maka, E.M.,Pyeatt, G.L.,Roggensack, S.J.,Holden, H.M.; Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.; Biochemistry, 51:9375-9383, 2012; PubMed: 23116432; DOI: 10.1021/bi3012737

Experimental method

X-RAY DIFFRACTION (1.6 Å)