4J7G

Crystal structure of EvaA, a 2,3-dehydratase in complex with dTDP-fucose and dTDP-rhamnose

Summary for 4J7G

• Entry DOI: 10.2210/pdb4j7g/pdb
• Related: 4J7H
• Descriptor: EvaA 2,3-dehydratase, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, [[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate, ... (4 entities in total)
• Functional Keywords: nudix hydrolase superfamily, dehydration, biosynthetic protein
• Biological source: Amycolatopsis orientalis
• Total number of polymer chains: 2
• Total formula weight: 108194.84

Authors

Holden, H.M.,Kubiak, R.L.,Thoden, J.B. (deposition date: 2013-02-13, release date: 2013-05-22, Last modification date: 2013-12-25)

• Primary citation: Kubiak, R.L.,Thoden, J.B.,Holden, H.M.; Structure of EvaA: A Paradigm for Sugar 2,3-Dehydratases.; Biochemistry, 52:2078-2088, 2013; PubMed: 23473392; DOI: 10.1021/bi400176n

Experimental method

X-RAY DIFFRACTION (1.7 Å)