3NYT

X-ray crystal structure of the WlbE (WpbE) aminotransferase from pseudomonas aeruginosa, mutation K185A, in complex with the PLP external aldimine adduct with UDP-3-amino-2-N-acetyl-glucuronic acid, at 1.3 angstrom resolution

Summary for 3NYT

• Entry DOI: 10.2210/pdb3nyt/pdb
• Related: 3NYS 3NYU
• Descriptor: Aminotransferase WbpE, (2S,3S,4R,5R,6R)-5-(acetylamino)-6-{[(R)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxy-4-{[(1E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}tetrahydro-2H-pyran-2-carboxylic acid (non-preferred name), SODIUM ION, ... (4 entities in total)
• Functional Keywords: aminotransferase, plp binding, nucleotide-sugar binding, transferase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 1
• Total formula weight: 40851.06

Authors

Holden, H.M.,Thoden, J.B. (deposition date: 2010-07-15, release date: 2010-07-28, Last modification date: 2023-09-06)

• Primary citation: Dow, G.T.,Gilbert, M.,Thoden, J.B.,Holden, H.M.; Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase.; Protein Sci., 26:586-599, 2017; PubMed: 28028852; DOI: 10.1002/pro.3109

Experimental method

X-RAY DIFFRACTION (1.301 Å)