3DR4

GDP-perosamine synthase K186A mutant from Caulobacter crescentus with bound sugar ligand

Summary for 3DR4

Entry DOI	10.2210/pdb3dr4/pdb
Related	3bn1 3dr7
Descriptor	Putative perosamine synthetase, [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S,5S,6R)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-6-methyltetrahydro-2H-pyran-2-yl dihydrogen diphosphate, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	perosamine, deoxysugar, pyridoxal phosphate, aspartate aminotransferase, o-antigen, transferase
Biological source	Caulobacter crescentus
Total number of polymer chains	4
Total formula weight	175326.01
Authors	Holden, H.M.,Cook, P.D.,Carney, A.E. (deposition date: 2008-07-10, release date: 2008-10-14, Last modification date: 2023-08-30)
Primary citation	Cook, P.D.,Carney, A.E.,Holden, H.M. Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase Biochemistry, 47:10685-10693, 2008 Cited by PubMed: 18795799 DOI: 10.1021/bi801309q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation