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PDB: 36 results

5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5FAF
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N184K pathological variant of gelsolin domain 2 (orthorhombic form)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Boni, F, Milani, M, Ricagno, s, Bolognesi, M, de Rosa, M.
Deposit date:2015-12-11
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Molecular basis of a novel renal amyloidosis due to N184K gelsolin variant.
Sci Rep, 6, 2016
6Q9Z
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BU of 6q9z by Molmil
Crystal structure of the pathological G167R variant of calcium-free human gelsolin,
Descriptor: GLYCEROL, Gelsolin, SULFATE ION
Authors:Boni, F, Scalone, E, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-18
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
6QBF
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BU of 6qbf by Molmil
Crystal structure of the pathological D187N variant of calcium-free human gelsolin.
Descriptor: GLYCEROL, Gelsolin, SODIUM ION, ...
Authors:Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-21
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.499 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
6Q9R
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BU of 6q9r by Molmil
Crystal structure of the pathological N184K variant of calcium-free human gelsolin
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-18
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
7P2B
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BU of 7p2b by Molmil
Crystal structure of human gelsolin amyloid mutant A551P
Descriptor: CHLORIDE ION, GLYCEROL, Gelsolin, ...
Authors:Bollati, M, de Rosa, M.
Deposit date:2021-07-05
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation.
Comput Struct Biotechnol J, 19, 2021
6QW3
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BU of 6qw3 by Molmil
Calcium-bound gelsolin domain 2
Descriptor: CALCIUM ION, Gelsolin
Authors:Scalone, E, Boni, F, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2019-03-05
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:High-resolution crystal structure of gelsolin domain 2 in complex with the physiological calcium ion.
Biochem.Biophys.Res.Commun., 518, 2019
4KA4
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BU of 4ka4 by Molmil
Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Z-DNA-binding protein 1
Authors:Athanasiadis, A, de Rosa, M, De Sanctis, D.
Deposit date:2013-04-22
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
To be Published
4HOB
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BU of 4hob by Molmil
The crystal structure of the Zalpha domain from Cyprinid Herpes virus 3
Descriptor: Putative uncharacterized protein, SULFATE ION
Authors:Tome, A.R, Kus, K, de Rosa, M, Paulo, L.M, Figueiredo, D, Athanasiadis, A.
Deposit date:2012-10-22
Release date:2013-09-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of a poxvirus-like zalpha domain from cyprinid herpesvirus 3
J.Virol., 87, 2013
5O2Z
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BU of 5o2z by Molmil
Domain swap dimer of the G167R variant of gelsolin second domain
Descriptor: ACETATE ION, CALCIUM ION, CITRATE ANION, ...
Authors:Boni, F, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2017-05-23
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein.
Hum. Mol. Genet., 27, 2018
4BND
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BU of 4bnd by Molmil
Structure of an atypical alpha-phosphoglucomutase similar to eukaryotic phosphomannomutases
Descriptor: ALPHA-PHOSPHOGLUCOMUTASE, GLYCEROL, SULFATE ION
Authors:Nogly, P, Matias, P.M, De Rosa, M, Castro, R, Santos, H, Neves, A.R, Archer, M.
Deposit date:2013-05-14
Release date:2013-10-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-Resolution Structure of an Atypical [Alpha]-Phosphoglucomutase Related to Eukaryotic Phosphomannomutases
Acta Crystallogr.,Sect.D, 69, 2013
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