7BR3
 
 | | Crystal structure of the protein 1 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R)-2,3-dihydroxypropyl dodecanoate, 4-[[(1R)-2-[5-(2-fluoranyl-3-methoxy-phenyl)-3-[[2-fluoranyl-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-bis(oxidanylidene)pyrimidin-1-yl]-1-phenyl-ethyl]amino]butanoic acid, ... | | 著者 | Cheng, L, Shao, Z. | | 登録日 | 2020-03-26 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode.
Nat Commun, 11, 2020
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5Z4D
 | | Structure of Tailor in complex with AGUU RNA | | 分子名称: | RNA (5'-R(*AP*GP*UP*U)-3'), Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-11 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4M
 | | Structure of TailorD343A with bound UTP and Mg | | 分子名称: | MAGNESIUM ION, Terminal uridylyltransferase Tailor, URIDINE 5'-TRIPHOSPHATE | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-11 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4C
 | | Crystal structure of Tailor | | 分子名称: | Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-10 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4J
 | | Structure of Tailor in complex with U4 RNA | | 分子名称: | RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-11 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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5Z4A
 | | Structure of Tailor in complex with AGU RNA | | 分子名称: | RNA (5'-R(*AP*GP*U)-3'), Terminal uridylyltransferase Tailor | | 著者 | Cheng, L, Li, F, Jiang, Y, Yu, H, Xie, C, Shi, Y, Gong, Q. | | 登録日 | 2018-01-10 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural insights into a unique preference for 3' terminal guanine of mirtron in Drosophila TUTase tailor.
Nucleic Acids Res., 47, 2019
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3ZIF
 | | Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | | 分子名称: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | | 著者 | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | | 登録日 | 2013-01-09 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates
Virology, 450, 2014
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3IZ3
 | | CryoEM structure of cytoplasmic polyhedrosis virus | | 分子名称: | Structural protein VP1, Structural protein VP3, Viral structural protein 5 | | 著者 | Cheng, L, Sun, J, Zhang, K, Mou, Z, Huang, X, Ji, G, Sun, F, Zhang, J, Zhu, P. | | 登録日 | 2010-09-14 | | 公開日 | 2011-03-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping.
Proc.Natl.Acad.Sci.USA, 108, 2011
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7ECA
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4X9B
 | | Crystal structure of Dscam1 isoform 4.44, N-terminal four Ig domains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.44, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-11 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4X9G
 | | Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains | | 分子名称: | Down Syndrome Cell Adhesion Molecule isoform 6.44, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-11 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.403 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4X9F
 | | Crystal structure of Dscam1 isoform 6.9, N-terminal four Ig domains | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Down Syndrome Cell Adhesion Molecule isoform 6.9, GLYCEROL, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-11 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4X5L
 | | Crystal structure of Dscam1 Ig7 domain, isoform 9 | | 分子名称: | Down syndrome cell adhesion molecule, isoform AM, SODIUM ION | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-05 | | 公開日 | 2015-12-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.374 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4WVR
 | | Crystal structure of Dscam1 Ig7 domain, isoform 5 | | 分子名称: | Down syndrome cell adhesion molecule, isoform AK | | 著者 | Chen, Q, Yu, Y, Li, S, Cheng, L. | | 登録日 | 2014-11-07 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4X83
 | | Crystal structure of Dscam1 isoform 7.44, N-terminal four Ig domains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-10 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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8JIL
 | | Cryo-EM structure of niacin bound ketone body receptor HCAR2-Gi signaling complex | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | 登録日 | 2023-05-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JII
 | | Cryo-EM structure of compound 9n and niacin bound ketone body receptor HCAR2-Gi signaling complex | | 分子名称: | 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | 登録日 | 2023-05-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JHY
 | | Cryo-EM structure of compound 9n bound ketone body receptor HCAR2-Gi signaling complex | | 分子名称: | 7-methyl-N-[(2R)-1-phenoxypropan-2-yl]-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | 登録日 | 2023-05-25 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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8JIM
 | | Cryo-EM structure of MMF bound ketone body receptor HCAR2-Gi signaling complex | | 分子名称: | (2Z)-4-methoxy-4-oxobut-2-enoic acid, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhao, C, Tian, X.W, Liu, Y, Cheng, L, Yan, W, Shao, Z.H. | | 登録日 | 2023-05-26 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Mol.Cell, 83, 2023
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4CIK
 | | plasminogen kringle 1 in complex with inhibitor | | 分子名称: | 5-[(2R,4S)-2-(phenylmethyl)piperidin-4-yl]-1,2-oxazol-3-one, PLASMINOGEN | | 著者 | Xue, Y, Johansson, C, Cheng, L, Pettersen, D, Gustafsson, D. | | 登録日 | 2013-12-10 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Discovery of the Fibrinolysis Inhibitor Azd6564, Acting Via Interference of a Protein-Protein Interaction.
Acs Med.Chem.Lett., 5, 2014
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4U6V
 | | Mechanisms of Neutralization of a Human Anti-Alpha Toxin Antibody | | 分子名称: | Alpha-hemolysin, Fab, antigen binding fragment, ... | | 著者 | Oganesyan, V.Y, Peng, L, Damschroder, M.M, Cheng, L, Sadowska, A, Tkaczyk, C, Sellman, B, Wu, H, Dall'Acqua, W.F. | | 登録日 | 2014-07-29 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody.
J.Biol.Chem., 289, 2014
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4X9I
 | | Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, isoform 9.44, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, cheng, L. | | 登録日 | 2014-12-11 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4XB8
 | | Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, cheng, L. | | 登録日 | 2014-12-16 | | 公開日 | 2015-12-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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4XB7
 | | Crystal structure of Dscam1 isoform 4.4, N-terminal four Ig domains | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down syndrome cell adhesion molecule, isoform 4.4, ... | | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | | 登録日 | 2014-12-16 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4.004 Å) | | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition
Sci Adv, 2, 2016
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5ZVS
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