1DCH
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![BU of 1dch by Molmil](/molmil-images/mine/1dch) | CRYSTAL STRUCTURE OF DCOH, A BIFUNCTIONAL, PROTEIN-BINDING TRANSCRIPTION COACTIVATOR | Descriptor: | DCOH (DIMERIZATION COFACTOR OF HNF-1), SULFATE ION | Authors: | Endrizzi, J.A, Cronk, J.D, Wang, W, Crabtree, G.R, Alber, T. | Deposit date: | 1995-01-24 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator. Science, 268, 1995
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1DEB
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![BU of 1deb by Molmil](/molmil-images/mine/1deb) | |
1EKX
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![BU of 1ekx by Molmil](/molmil-images/mine/1ekx) | THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE) | Descriptor: | ASPARTATE TRANSCARBAMOYLASE, CALCIUM ION, N-(PHOSPHONACETYL)-L-ASPARTIC ACID | Authors: | Endrizzi, J.A, Beernink, P.T, Alber, T, Schachman, H.K. | Deposit date: | 2000-03-09 | Release date: | 2000-05-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration. Proc.Natl.Acad.Sci.USA, 97, 2000
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2O7A
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![BU of 2o7a by Molmil](/molmil-images/mine/2o7a) | T4 lysozyme C-terminal fragment | Descriptor: | ACETATE ION, CHLORIDE ION, Lysozyme | Authors: | Echols, N, Kwon, E, Marqusee, S.M, Alber, T. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (0.84 Å) | Cite: | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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2O60
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![BU of 2o60 by Molmil](/molmil-images/mine/2o60) | |
2O5G
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![BU of 2o5g by Molmil](/molmil-images/mine/2o5g) | Calmodulin-smooth muscle light chain kinase peptide complex | Descriptor: | CALCIUM ION, Calmodulin, SULFATE ION, ... | Authors: | Valentine, K.G, Ng, H.L, Schneeweis, J.K, Kranz, J.K, Frederick, K.K, Alber, T, Wand, A.J. | Deposit date: | 2006-12-05 | Release date: | 2007-12-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Ultrahigh resolution crystal structure of calmodulin-smooth muscle light kinase peptide complex To be Published
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2O79
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![BU of 2o79 by Molmil](/molmil-images/mine/2o79) | T4 lysozyme with C-terminal extension | Descriptor: | CHLORIDE ION, GLYCEROL, Lysozyme, ... | Authors: | Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S. | Deposit date: | 2006-12-10 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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2O4W
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![BU of 2o4w by Molmil](/molmil-images/mine/2o4w) | T4 lysozyme circular permutant | Descriptor: | CHLORIDE ION, Lysozyme | Authors: | Llinas, M, Crowder, S.M, Echols, N, Alber, T, Marqusee, S. | Deposit date: | 2006-12-05 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Exploring subdomain cooperativity in T4 lysozyme I: Structural and energetic studies of a circular permutant and protein fragment. Protein Sci., 16, 2007
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2O6N
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![BU of 2o6n by Molmil](/molmil-images/mine/2o6n) | |
2OZ5
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![BU of 2oz5 by Molmil](/molmil-images/mine/2oz5) | Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS | Descriptor: | Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID | Authors: | Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2007-02-23 | Release date: | 2007-05-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB. Structure, 15, 2007
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3OUN
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![BU of 3oun by Molmil](/molmil-images/mine/3oun) | |
3ORI
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![BU of 3ori by Molmil](/molmil-images/mine/3ori) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 1) | Descriptor: | MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Lombana, T.N, Echols, N, Good, M.C, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3OUK
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![BU of 3ouk by Molmil](/molmil-images/mine/3ouk) | |
3ORL
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![BU of 3orl by Molmil](/molmil-images/mine/3orl) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 3) | Descriptor: | MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Echols, N, Lombana, T.N, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3ORP
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![BU of 3orp by Molmil](/molmil-images/mine/3orp) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 5) | Descriptor: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3OTV
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![BU of 3otv by Molmil](/molmil-images/mine/3otv) | |
3ORO
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![BU of 3oro by Molmil](/molmil-images/mine/3oro) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4) | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3OXH
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![BU of 3oxh by Molmil](/molmil-images/mine/3oxh) | Mycobacterium tuberculosis kinase inhibitor homolog RV0577 | Descriptor: | CHLORIDE ION, PARA-MERCURY-BENZENESULFONIC ACID, RV0577 PROTEIN, ... | Authors: | Echols, N, Flynn, E.M, Stephenson, S, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-21 | Release date: | 2011-10-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA. Biochemistry, 2017
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3ORK
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![BU of 3ork by Molmil](/molmil-images/mine/3ork) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 2) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Echols, N, Lombana, T.N, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3ORM
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![BU of 3orm by Molmil](/molmil-images/mine/3orm) | Mycobacterium tuberculosis PknB kinase domain D76A mutant | Descriptor: | MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3ORT
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![BU of 3ort by Molmil](/molmil-images/mine/3ort) | Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 6) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3OUV
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![BU of 3ouv by Molmil](/molmil-images/mine/3ouv) | |
3RMR
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![BU of 3rmr by Molmil](/molmil-images/mine/3rmr) | |
1RWL
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![BU of 1rwl by Molmil](/molmil-images/mine/1rwl) | Extracellular domain of Mycobacterium tuberculosis PknD | Descriptor: | CADMIUM ION, Serine/threonine-protein kinase pknD | Authors: | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-12-16 | Release date: | 2004-04-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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1QSC
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![BU of 1qsc by Molmil](/molmil-images/mine/1qsc) | CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF2 IN A COMPLEX WITH A PEPTIDE FROM THE CD40 RECEPTOR | Descriptor: | CD40 RECEPTOR, TNF RECEPTOR ASSOCIATED FACTOR 2 | Authors: | McWhirter, S.M, Pullen, S.S, Holton, J.M, Crute, J.J, Kehry, M.R, Alber, T. | Deposit date: | 1999-06-20 | Release date: | 1999-08-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic analysis of CD40 recognition and signaling by human TRAF2. Proc.Natl.Acad.Sci.USA, 96, 1999
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